KEGG   Pteropus vampyrus (large flying fox): 105306828
Entry
105306828         CDS       T07815                                 
Name
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial isoform X1
  KO
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
Organism
pvp  Pteropus vampyrus (large flying fox)
Pathway
pvp00140  Steroid hormone biosynthesis
pvp01100  Metabolic pathways
pvp04913  Ovarian steroidogenesis
pvp04925  Aldosterone synthesis and secretion
pvp04927  Cortisol synthesis and secretion
pvp04934  Cushing syndrome
Module
pvp_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Brite
KEGG Orthology (KO) [BR:pvp00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    105306828
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    105306828
   04925 Aldosterone synthesis and secretion
    105306828
   04927 Cortisol synthesis and secretion
    105306828
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    105306828
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:pvp00199]
    105306828
Enzymes [BR:pvp01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6  cholesterol monooxygenase (side-chain-cleaving)
     105306828
Cytochrome P450 [BR:pvp00199]
 Cytochrome P450, animal type
  CYP11 family
   105306828
SSDB
Motif
Pfam: p450
Other DBs
NCBI-GeneID: 105306828
NCBI-ProteinID: XP_011380364
UniProt: A0A6P3RVG7
LinkDB
Position
Unknown
AA seq 521 aa
MLARGLPLRSVLVKGCQPLLSAPQEGPWHLRVPTREGARISTRVPRPFSEIPSPGDNGWL
NLYRFWREKGSQNFHHHQFQNFQKYGPIYREKLGTMESVFIVDPEDIAILFKYEGSTPER
YFIPPWVAYHQHYQRPIGVLFKKSGAWKKDRLALNPEVMAPEAMKNFVSLLDPVSRDFVS
ILHRRIEQQGSGKFSGDFSNDLFRFAFESITNVIFGERLGMLEEIVDPESQQFIDAVYQM
FHTSVPMLMLPPDLFRLFKTKTWRDHAAAWDVIFSRAEKYIQNFSLDLRQKKDFNDIYPG
ILYRLLENNKLLFEDIKANITELLAGGVDTTSMTLQWHLYEMARSLTVQEMLREEVLAAR
RQAGEDMNRMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLQDYMIPAKTLVQVSTY
TLGRDPNFFLNPSKFDPTRWLGKNKDLTHFRHLGFGWGIRQCLGRRIAEVEMTLFLIHIL
ENFRVEIQHLNDVGTMFNLILMPDQPIFFTFRPFTQDPPPA
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgctggcccgggggcttcctttgcgctcagtcttggtcaaaggctgccagcccctcttg
agtgccccacaggagggcccatggcatctcagggtgcccactagagagggagcccgcatt
tccactcgagtccctcgccctttcagtgagataccctctcctggtgacaacggctggcta
aatctgtaccgtttctggagagagaagggttcacagaatttccaccaccaccaattccag
aacttccagaaatacggccctatttacagggagaagcttggcaccatggagtcggttttt
atcgttgaccctgaggacatagccattctttttaagtatgagggttccacaccagaacga
tatttcatcccgccctgggttgcctatcaccagcattaccagagacccatcggagtctta
ttcaagaagtcaggagcctggaaaaaagaccggctggccctaaacccggaggtgatggct
ccagaagccatgaagaacttcgtctccctgctggacccagtgtcccgggacttcgtcagc
atcctgcacaggcgcatcgagcagcagggctctggaaagttctcaggggacttcagtaat
gacttgtttcgctttgcctttgagtctatcaccaatgtcatatttggagagcgtttaggg
atgctggaggagatagtggaccctgagtcccagcagttcattgacgccgtttaccagatg
ttccacaccagcgtccccatgctcatgctccccccagacctgttccgtttgttcaagacc
aagacgtggcgggatcatgcggccgcatgggacgtgattttcagtagagctgaaaaatat
atccagaacttctctttggacctcagacagaaaaaagacttcaacgacatttacccgggc
atcctctaccgcctcctggaaaacaacaagctgctcttcgaggacatcaaggccaatatt
acggagttgttggctgggggtgtggacacgacatccatgacgttgcagtggcacttgtac
gagatggcacgcagcctgacggtgcaggagatgctgcgggaggaggttctggctgcccgg
cgccaggccggggaagacatgaacaggatgctgcagttggtcccactcctaaaagctagc
atcaaggagacattgagactccaccccatctccgtgaccctgcagagatacctagtaaat
gacttggttctacaagattatatgattcccgccaagacattggtacaggtgtctacttat
accttgggccgagaccccaacttcttcctcaatcccagcaaatttgaccccactcgatgg
ctgggtaaaaacaaagacctcacccacttccgccacctgggcttcggctggggaattcgg
cagtgcctgggccggaggatcgcagaggttgagatgaccctcttcctcatccatattctg
gagaatttcagagttgaaatccagcatctcaatgacgtgggcacaatgttcaacctcatc
ctgatgcctgaccagcccattttcttcaccttccgaccttttacccaggacccaccccca
gcatga

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