KEGG   Triplophysa dalaica: 130436970
Entry
130436970         CDS       T09616                                 
Symbol
mthfd1b
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
tdw  Triplophysa dalaica
Pathway
tdw00670  One carbon pool by folate
tdw01100  Metabolic pathways
tdw01240  Biosynthesis of cofactors
tdw04981  Folate transport and metabolism
Module
tdw_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:tdw00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    130436970 (mthfd1b)
 09150 Organismal Systems
  09154 Digestive system
   04981 Folate transport and metabolism
    130436970 (mthfd1b)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:tdw04147]
    130436970 (mthfd1b)
Enzymes [BR:tdw01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     130436970 (mthfd1b)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     130436970 (mthfd1b)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     130436970 (mthfd1b)
Exosome [BR:tdw04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   130436970 (mthfd1b)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-GeneID: 130436970
NCBI-ProteinID: XP_056624018
LinkDB
Position
15:18425827..18451776
AA seq 934 aa
MSAQIISGKNVSAQLRERLKNEVDAMRTTHPNFKPGLVVLQVGDREDSNLYISMKLKAAA
EIGINAVHVKLPQTATENEIMSRVHEINENSSVHGLIVQLPLDSIHTINTERVINAVSPE
KDVDGLTSINAGKLARGDIGDCFIPCTPKGCMELIKQTGVPLAGKRAVVIGRSKIVGAPM
HDLLLWNHATVTTCHSKTADLPSEVRMADILVTAIGKPEMVRGDWLKKGAVVIDCGINTV
PDSSRPSGKKVVGDVHYDSAKDHAAFITPVPGGVGPMTVAMLMENTVLSAKQFLQAKEPG
KWNISYTKLNLQCPVPSDIVISRSCVPKPIEHLSKEIGIFPDELELYGETKAKVQLKMLD
RLQAQPNGKYVVVTGITPTPLGEGKSTTTIGLVQALGAHLKHNAFACVRQPSQGPTFGIK
GGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDARIFHEATQSDKALFNRLVP
LTDGQRKFSPVQTNRLKNLGIEKNDPSTLTEKEISSFVRLDIDPETISWQRVVDTNDRFL
RQITIGQSPTEKGFTRTAQFDITVASEIMAVLALTTSLEDMRQRLSKMVVASSRSGQPVT
TEDLGVCGALTVLMRDAIKPNLMQTLEGNPVFVHAGPFANIAHGNSSILADKIALKLVGP
QGFVVTEAGFGADIGMEKFFNIKCRYSGLRPHVVVLVATVRALKMHGGGPKVTAGMPLPK
EYVEENLALLEAGCGNMKKQVQNAQLFGIPVVVAVNAFKTDTDSEVDLVCKLAKEAGAFD
AVKSSHWADGGAGAVDLARAVEKAAESPSSFKLLYDTELPIVNKIRIIAQKIYGADDIEL
LPEAQQKVDLYNKQGFGNLPICMAKTHLSLSHDAEKKGVPTGFILPIRDIRASVGAGFLY
PLVGTMPTIPGLPTRPCFYDIDLDPESGNIVGLF
NT seq 2805 nt   +upstreamnt  +downstreamnt
atgtcagcccaaatcatcagcgggaagaatgtttcagctcagctcagagagaggctgaag
aatgaggtggatgccatgaggactacacacccaaattttaaaccaggtcttgtagtctta
caggtgggagacagagaggactctaacctgtacataagtatgaagctgaaagccgctgct
gagattggaatcaatgctgtacatgtgaagcttccacagaccgctactgaaaatgagatt
atgtccagggttcatgaaatcaatgagaattccagtgttcatggactcatagtgcagctg
cccctcgactccattcacactattaatacagagagggtcatcaacgctgtgtctccagag
aaagatgttgatgggttgaccagtataaatgcaggaaaacttgcccgtggtgatattgga
gactgttttataccatgtactccgaaaggatgcatggagctcatcaaacaaacaggtgtg
cctttggcgggaaaaagggctgtggtgattggccgcagtaagattgtgggtgcaccaatg
catgaccttcttctttggaatcatgctactgtgacaacctgtcattccaagactgcagac
ctgccctctgaggtgagaatggcagacatcctggtgactgcgattggaaaaccagagatg
gttcgaggagactggctaaagaagggagccgtggtcattgactgtggtattaacaccgtc
cctgacagcagcagacctagcggaaagaaagtcgttggggacgttcactatgattctgcc
aaagatcatgctgcatttatcacacctgtacctggaggtgtcggccctatgaccgtagcc
atgcttatggagaacacagttttgagtgccaaacaattccttcaagcaaaagaaccaggg
aagtggaacataagttacacaaaactcaacctgcaatgccctgttccaagcgatattgtc
atctctcgctcctgtgtacccaaacccattgagcatcttagtaaggaaattggtattttt
ccggatgagcttgaactttatggtgaaaccaaggccaaagtccagctgaaaatgcttgat
cggctgcaggcacaaccaaatggcaaatatgtggttgtaactggaatcacaccgactcct
ctgggtgaaggaaagagcacaactaccataggcttggttcaggcactcggtgctcatctc
aaacataatgcatttgcgtgtgttcgccaaccatcacaagggccaacatttggcatcaaa
ggtggtgctgctggagggggctactctcaagttattcctatggaagagttcaatcttcat
ttgactggtgacattcatgctataacagcagccaataacttggttgctgctgcaattgat
gctcgtatcttccatgaagccactcaatctgataaggctctctttaatcgcttggtacca
ttgactgatggtcagagaaagttttctccagtccagaccaacagacttaaaaatcttggc
atagaaaaaaatgaccccagcacattaacagagaaggagatctcgtccttcgtcaggcta
gacattgaccctgaaaccatcagctggcagcgagtggtggacacaaatgatcgtttcctg
agacaaataaccattggccagtctccaactgagaagggtttcaccagaactgctcagttt
gacatcaccgtggccagtgagattatggcagttttagctcttaccactagtctggaggat
atgagacagaggctatcgaaaatggtggtggccagcagccgcagcggtcagcctgtcacc
acagaggatttgggagtgtgtggagctttgactgtactcatgcgagatgctatcaaaccc
aacctcatgcagacacttgagggaaatcctgtgtttgttcacgctggaccttttgcaaac
attgcacatggaaactcatcaatcctggctgataaaattgctctgaaactagttgggcct
cagggatttgtggtcactgaagcaggttttggagcagatattgggatggagaagtttttc
aacatcaagtgtcgttattctggcctcaggcctcatgttgtggttctggttgccacggtt
cgagcactaaagatgcatggaggtggacccaaggtcacggcaggtatgcctctgccaaaa
gagtatgttgaggagaatctggcactgctggaagctggatgtggtaacatgaagaagcaa
gtgcagaatgctcaactttttggaattcctgtagttgtagctgtcaatgcgttcaagacc
gacacagattctgaagtagatctggtctgtaaattggctaaagaagcaggggcatttgat
gctgtgaagtcttctcactgggctgatggaggtgccggtgctgttgatcttgccagagca
gtggaaaaagctgcagagtcacccagttctttcaaattgctttatgatactgagctaccc
attgtaaataagatcagaattattgcgcaaaagatctatggtgcagatgacattgaactc
ttgccagaggcccaacagaaagtggacctgtacaacaaacagggttttggaaatttaccc
atatgcatggcaaagacccatctgtctctctcacatgatgctgaaaagaaaggtgtccca
actggctttatccttcccatccgtgacattcgtgccagtgtaggggcaggctttctctac
ccactggttggcacaatgccaactattccaggccttccaactcgtccctgtttctatgac
attgatcttgaccctgagagtggaaatatagttggtctgttctaa

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