Ursus arctos (brown bear): 113263646
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Entry
113263646 CDS
T05909
Symbol
IGF1R
Name
(RefSeq) insulin-like growth factor 1 receptor
KO
K05087
insulin-like growth factor 1 receptor [EC:
2.7.10.1
]
Organism
uah
Ursus arctos (brown bear)
Pathway
uah01521
EGFR tyrosine kinase inhibitor resistance
uah01522
Endocrine resistance
uah04010
MAPK signaling pathway
uah04014
Ras signaling pathway
uah04015
Rap1 signaling pathway
uah04066
HIF-1 signaling pathway
uah04068
FoxO signaling pathway
uah04114
Oocyte meiosis
uah04140
Autophagy - animal
uah04144
Endocytosis
uah04150
mTOR signaling pathway
uah04151
PI3K-Akt signaling pathway
uah04152
AMPK signaling pathway
uah04211
Longevity regulating pathway
uah04213
Longevity regulating pathway - multiple species
uah04510
Focal adhesion
uah04520
Adherens junction
uah04550
Signaling pathways regulating pluripotency of stem cells
uah04730
Long-term depression
uah04913
Ovarian steroidogenesis
uah04914
Progesterone-mediated oocyte maturation
uah05200
Pathways in cancer
uah05202
Transcriptional misregulation in cancer
uah05205
Proteoglycans in cancer
uah05214
Glioma
uah05215
Prostate cancer
uah05218
Melanoma
uah05224
Breast cancer
uah05225
Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:
uah00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
113263646 (IGF1R)
04014 Ras signaling pathway
113263646 (IGF1R)
04015 Rap1 signaling pathway
113263646 (IGF1R)
04066 HIF-1 signaling pathway
113263646 (IGF1R)
04068 FoxO signaling pathway
113263646 (IGF1R)
04151 PI3K-Akt signaling pathway
113263646 (IGF1R)
04152 AMPK signaling pathway
113263646 (IGF1R)
04150 mTOR signaling pathway
113263646 (IGF1R)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
113263646 (IGF1R)
04140 Autophagy - animal
113263646 (IGF1R)
09143 Cell growth and death
04114 Oocyte meiosis
113263646 (IGF1R)
09144 Cellular community - eukaryotes
04510 Focal adhesion
113263646 (IGF1R)
04520 Adherens junction
113263646 (IGF1R)
04550 Signaling pathways regulating pluripotency of stem cells
113263646 (IGF1R)
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
113263646 (IGF1R)
04914 Progesterone-mediated oocyte maturation
113263646 (IGF1R)
09156 Nervous system
04730 Long-term depression
113263646 (IGF1R)
09149 Aging
04211 Longevity regulating pathway
113263646 (IGF1R)
04213 Longevity regulating pathway - multiple species
113263646 (IGF1R)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
113263646 (IGF1R)
05202 Transcriptional misregulation in cancer
113263646 (IGF1R)
05205 Proteoglycans in cancer
113263646 (IGF1R)
09162 Cancer: specific types
05225 Hepatocellular carcinoma
113263646 (IGF1R)
05214 Glioma
113263646 (IGF1R)
05218 Melanoma
113263646 (IGF1R)
05215 Prostate cancer
113263646 (IGF1R)
05224 Breast cancer
113263646 (IGF1R)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
113263646 (IGF1R)
01522 Endocrine resistance
113263646 (IGF1R)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
uah01001
]
113263646 (IGF1R)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
uah04090
]
113263646 (IGF1R)
Enzymes [BR:
uah01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
113263646 (IGF1R)
Protein kinases [BR:
uah01001
]
Receptor tyrosine kinases (RTK)
INSR family [OT]
113263646 (IGF1R)
CD molecules [BR:
uah04090
]
Proteins
113263646 (IGF1R)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
Furin-like
Pkinase
fn3
Kinase-like
Motif
Other DBs
NCBI-GeneID:
113263646
NCBI-ProteinID:
XP_026366159
LinkDB
All DBs
Position
Unknown
AA seq
1366 aa
AA seq
DB search
MKSGSGGGSPTSLWGLLFFSAALSLWPTSGEICGPGIDIRNDYQQLKRLENCTVIEGYLH
ILLISKAEDYRSYRFPKLTVITEYLLLFRVAGLESLGDLFPNLTVIRGWKLFYNYALVIF
EMTNLKDIGLYNLRNITRGAIRIEKNADLCYLSTVDWSLILDAVSNNYIVGNKPPKECGD
LCPGTMEEKPLCEKTTINNEYNYRCWTTNRCQKMCPSACGKRACTENNECCHPECLGSCS
APDNDTACVACRHYYYAGVCVPTCPPNTYRFEGWRCVDRDFCANIPSAESSDSEGFVIHD
GECMQECPSGFIRNGSQSMYCIPCEGPCPKVCEEEKKTKTIDSVTSAQMLQGCTIFKGNL
LINIRRGNNIASELENFMGLIEVVTGYVKIRHSHALVSLSFLKNLRQILGEEQLEGNYSF
YVLDNQNLQQLWDWDHRNLTIKAGKMYFAFNPKLCVSEIYRMEEVTGTKGRQSKGDINTR
NNGERASCESDVLHFTSTTTWKNHIIIRWHRYRPPDYRDLISFTVYYKEAPFKNVTEYDG
QDACGSNSWNMVDVDLPPNKDVDPGILLQGLKPWTQYAVYVKAVTLTMVNDHIRGAKSEI
LYIRTNASVPSIPLDVLSASNSSSQLIVKWNPPSLPNGNLSYYIVRWQRQPQDSYLYRHN
YCSKDKIPIRKYADGTIDVEEVTENPKTEVCGGEKGPCCACPKTEAEKQAEKEEAEYRKV
FENFLHNSIFVPRPERKRRDVTQITNTTMSSRGRNSTVADTYNITDPEELETEYPFFESR
VDNKERTVISNLRPFTLYRIDIHSCNHEAEKLGCSASNFVFARTMPAEGADDIPGPVTWE
SRPENSIFLKWPEPENPNGLILMYEIKYGSQIEDQRECVSRQEYRKYGGAKLNRLNPGNY
TARIQATSLSGNGSWTDPVFFYVPAKITYENFIHLIIALPVAVLLIVGGLVIMLYVFHRK
RNNSRLGNGVLYASVNPEYFSAADVYVPDEWEVAREKITMSRELGQGSFGMVYEGVAKGV
VKDEPETRVAIKTVNEAASMRERIEFLNEASVMKEFNCHHVVRLLGVVSQGQPTLVIMEL
MTRGDLKSYLRSLRPEIENNPVLAPPSLSKMIQMAGEIADGMAYLNANKFVHRDLAARNC
MVAEDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMSPESLKDGVFTTHSDVWSFGVV
LWEIATLAEQPYQGLSNEQVLRFVMEGGLLDKPDNCPDMLFELMRMCWQYNPKMRPSFLE
IISSIKDEMEPGFREVSFYYSEENKPPEPEELDLEPENMESVPLDPSASSSSLPLPDRHS
GHKAENGPGPGVLVLRASFDERQPYAHMNGGRKNERALPLPQSSTC
NT seq
4101 nt
NT seq
+upstream
nt +downstream
nt
atgaagtctggctccggaggagggtccccgacctcgctgtgggggctcctgtttttctcc
gccgcgctctcgctctggccgacgagtggagaaatctgcgggccgggcatcgacatccgc
aacgactatcagcagctgaagcgtctggagaactgcacggtgatcgagggctacctccac
atcttgctcatctccaaggcagaggactaccgcagctaccgcttccccaagctcacggtc
atcaccgagtacctgctgctgttccgcgtggccggcctcgagagcctcggggacctcttc
ccgaacctcacggtcatccgcggctggaaactcttctacaattacgccctggtcatcttt
gagatgaccaatctcaaggatattgggctttacaatctgaggaacattactcggggggcc
atcaggattgagaaaaatgccgacctctgttacctctccacggtggactggtccctgatc
ctggacgcggtgtccaataactacatcgtggggaacaaacccccaaaggaatgcggggac
ctgtgtccggggacgatggaggagaagcccttgtgcgagaagacgaccatcaacaacgag
tacaactaccgctgctggactacaaaccgctgccagaaaatgtgcccgagcgcgtgcggg
aagcgagcgtgcaccgagaacaacgagtgctgtcaccccgagtgtctgggcagctgcagc
gcgccggacaacgacacggcctgcgtggcctgcaggcattactactacgccggcgtctgc
gtgcccacctgcccgcccaacacctaccgcttcgagggctggcgctgcgtggaccgcgac
ttctgtgccaacatccccagcgccgagagcagcgactccgaggggttcgtgatccacgac
ggcgagtgcatgcaggagtgcccctccgggttcatccggaatggcagtcagagtatgtac
tgcatcccttgcgaaggtccttgccccaaggtctgtgaggaagagaagaaaacaaagacc
attgattctgttacctctgctcaaatgctccaaggatgcaccatcttcaagggcaatttg
ctcattaacatccgccgaggcaataacattgcctcggaactggagaacttcatggggctc
atcgaggtggtgacaggctacgtgaagattcgccattcccacgccttggtctccttgtcc
ttcctaaaaaaccttcgccagatcttaggagaggagcagctggaggggaactactccttc
tacgtccttgacaaccagaacttgcagcagctgtgggactgggaccaccgcaacctgacc
atcaaagctgggaaaatgtactttgctttcaatcccaagttgtgcgtctccgagatttac
cgcatggaggaagtgacagggactaaggggcgccagagcaaaggggacataaacaccagg
aacaacggagagcgagcctcctgtgaaagcgacgtcctgcacttcacctctacgaccaca
tggaagaatcacatcatcataaggtggcaccgttaccggccccccgactacagggacctc
atcagcttcactgtctactacaaggaagcaccttttaaaaacgtcacggagtacgatggc
caggatgcctgtggctccaacagctggaacatggtggatgtggacctccctcccaacaag
gacgtcgatcctggcattttactgcagggactgaagccctggacgcagtatgccgtgtat
gtcaaggcggtgaccctcaccatggtgaacgaccacatccgtggggccaagagtgaaatc
ttgtacattcgtaccaatgcttcagttccttccattcccctggacgttctgtccgcgtcc
aactcgtcttctcagctcatcgtgaagtggaacccgccgtccctgcccaacgggaacctc
agttactacatcgtgaggtggcagcggcagcctcaggacagctacctgtaccggcacaat
tactgctccaaagacaaaatccccatcaggaagtatgccgacggcaccatcgacgtcgaa
gaggtgacggagaatcccaagaccgaggtgtgcggcggagagaaggggccttgctgcgcc
tgccccaaaaccgaggccgagaagcaggccgagaaggaggaggccgagtaccgcaaagtc
ttcgagaacttcctgcacaactccatctttgtgcccagaccggaaaggaagcggagagac
gtcacacaaatcaccaacaccaccatgtccagccgaggcaggaacagcacagtggcggac
acctataatatcacagacccagaagagctcgagacagaataccctttctttgagagcaga
gtagataacaaggagagaactgtcatctctaacctccggccttttactttgtaccgcatt
gacatccacagctgtaaccatgaggctgagaagctgggctgcagcgcctccaactttgtt
tttgcaagaaccatgcctgcagaaggagcagatgacattcctgggccggtgacctgggag
tcgaggcctgaaaactccatctttctaaagtggccagaacctgagaatcccaatggattg
attctaatgtatgaaataaaatacggatcacaaatcgaggatcagcgggaatgtgtatcc
agacaggagtacaggaaatatggaggtgccaagcttaaccggctcaacccggggaactat
acagcccggatccaggccacctctctctccgggaatgggtcgtggacggatcctgtgttc
ttctatgtcccagccaaaataacgtatgaaaacttcatccatctgatcatagctctgccc
gttgccgtcctgttgatagtgggagggctggttataatgttgtacgtcttccacaggaaa
agaaataacagcaggctggggaatggagtgctgtacgcgtccgtgaacccagagtacttc
agcgccgccgacgtgtacgtacctgacgagtgggaggttgctcgagagaagatcaccatg
agccgagagctgggccagggctcctttgggatggtatacgaaggagtcgccaaaggcgtg
gttaaagatgagcccgaaaccagggtggccattaaaacagtgaacgaggctgcgagcatg
cgcgaaaggattgaatttctcaatgaggcttcagtgatgaaggagttcaattgtcaccac
gtggtgcggttgctgggcgtggtgtcccagggccagccgacgctggtcatcatggaactg
atgacacggggggatctcaaaagctatctcaggtctctgaggccagaaatagagaataat
ccagtcctagcacctccaagcctgagcaagatgatccagatggctggggagattgcagat
ggcatggcatacctcaacgccaacaagtttgtccacagagaccttgctgcccggaactgc
atggtggccgaagatttcacggtcaaaatcggagatttcggtatgacgagagacatctat
gagacagactattaccggaaaggaggaaaggggctgctgcctgtgcgctggatgtccccc
gagtctctcaaggatggagtcttcaccactcactctgacgtctggtccttcggggtcgtg
ctctgggagattgccacgctggccgaacagccataccagggcttgtccaacgagcaggtc
cttcgcttcgtgatggagggcggccttctggacaagccggacaactgccccgacatgctg
tttgaactgatgcgcatgtgctggcagtacaaccccaagatgaggccttccttcctggag
atcatcagcagcatcaaggacgagatggagcccggcttccgggaggtctccttctactac
agcgaggagaacaagccgcccgagccggaggagctggacctggagcccgagaacatggag
agcgtccccctggacccctccgcctcctcgtcctccctgccgctgcccgacagacactca
ggacacaaggccgagaacggcccaggccccggcgtgctggtcctccgagccagcttcgat
gagagacagccttacgcgcacatgaacgggggacgcaagaacgagagggccttgcctctg
ccccagtcttcgacctgctga
DBGET
integrated database retrieval system
