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International Journal of Molecular Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Micronutrients in Metabolic Health

edited by

Adaikala Antonysunil

submission deadline 20 Nov 2024 | 5 articles | Viewed by 24786 | Submission Open

Keywords: micronutrients; vitamin B12; vitamin D; epigenetics; obesity; type 2 diabetes; gestational diabetes; insulin resistance; cardiovasular disease; maternal and fetal programming

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Latest Review Papers in Molecular Neurobiology 2024

edited by

Anna Atlante

submission deadline 20 Nov 2024 | 8 articles | Viewed by 21158 | Submission Open

Keywords: neurobiology; neurochemistry; neurology; neuropathology; neurophysiology; neuropharmacology; neurogenetics; neuro-oncology; aging neuroscience; neurotrauma; neurogenesis; neurotransmitter; neuroinflammation; neuroendocrine tumor; neurodegenerative diseases

(This special issue belongs to the Section Molecular Neurobiology)

Mitochondria in Human Health and Disease 2.0

edited by

Anna-Maria Psarra

submission deadline 20 Nov 2024 | 9 articles | Viewed by 20505 | Submission Open

Keywords: OXPHOS; mitochondrial transcription; mitochondrial– nuclear interactions; mitochondrial– ER interactions; mitochondrial bioenergetics; mitochondrial fusion/fission; apoptosis; mitophagy; ROS– mitochondrial oxidative defense systems; neurodegenerative diseases; mitochondrial myopathies; mitochondrial diseases; mitochondrial disorders in cancer; mitochondria and inflammation; Ca2+ signaling

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

RNA Virus Mechanisms: From Molecular Insights to Therapeutic Strategies

edited by

Qibin Geng

submission deadline 20 Nov 2024 | 6 articles | Viewed by 18409 | Submission Open

Keywords: RNA virus mechanisms; viral pathogenesis; host– virus interactions; antiviral drug discovery; vaccine development; RNA virus epidemiology; RNA virus structure; RNA virus evolution

(This special issue belongs to the Section Molecular Microbiology)

Advanced Progress and Application of Photodynamic Therapy

edited by

Montserrat Fernández-Guarino

submission deadline 20 Nov 2024 | 4 articles | Viewed by 18396 | Submission Open

Keywords: photodynamic therapy; photobiology; light sources; illumination; light emitting diodes (LED); laser; photosensitizer; methylamoninolevunlic acid; delta aminolevulinic acid

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

The Advances in Antimicrobial Biomaterials

edited by

Hah Young Yoo

and

Jin Cheol Yoo

submission deadline 20 Nov 2024 | 7 articles | Viewed by 15619 | Submission Open

Keywords: biomaterials; biopolymers production; antimicrobial agents; antimicrobial activity; natural antibiotics; antioxidants; bioelastomers; food packaging

(This special issue belongs to the Section Materials Science)

Molecular Mechanisms of mRNA Transcriptional Regulation: 2nd Edition

edited by

Andrey Turchinovich

submission deadline 20 Nov 2024 | 7 articles | Viewed by 15119 | Submission Open

Keywords: transcriptoion factors (TFs); cis-regulatory elements (CREs); long non-coding RNAs (lncRNAs); short non-coding RNAs (sncRNAs); small nuclear RNAs (snRNAs); microRNA (miRNA); circular RNA (circRNA); DNA methylation; chromatin regulators

(This special issue belongs to the Section Biochemistry)

Essential Molecules in Life: Regulation, Defense, and Longevity

edited by

José Antonio Lupiáñez

Amalia Pérez-Jiménez

and

Eva E. Rufino Palomares

submission deadline 20 Nov 2024 | 8 articles | Viewed by 14945 | Submission Open

Keywords: glucose metabolism and its regulation; enzimology and kinetics; metabolism and evolution; cell growth; protein synthesis and degradation; cell proliferation and apoptosis; cancer; metastasis and angiogenesis; oxidative stress; genomic; proteomic and metab

(This special issue belongs to the Section Molecular Biology)

Recent Approaches for Wound Treatment—2nd Edition

edited by

César Viseras

Luana Perioli

and

Cinzia Pagano

submission deadline 20 Nov 2024 | 7 articles | Viewed by 14829 | Submission Open

(This special issue belongs to the Section Molecular Pharmacology)

Epilepsy: From Molecular Basis to Therapy

edited by

Henry Hing Cheong Lee

submission deadline 20 Nov 2024 | 11 articles | Viewed by 14361 | Submission Open

Keywords: genetic epilepsy; post-traumatic epilepsy; neurodevelopmental disorder; glutamate; GABA; ionic homeostasis; disease-modifying therapy; in vitro; in vivo; animal model; gene replacement therapy; gene editing; protein misfolding; small molecule; pharmacokinetics; pharmacodynamics; translational research; biomarker; clinical trial

(This special issue belongs to the Section Molecular Neurobiology)

Mechanism of Redox Signal Transduction in Plants

edited by

Yi Han

and

Kangdi Hu

submission deadline 20 Nov 2024 | 3 articles | Viewed by 13408 | Submission Open

Keywords: reactive oxygen species; reactive nitrogen species; hydrogen sulfide; persulfidation; nitrosation; sulfenylation; redox modification; redox signaling

(This special issue belongs to the Section Molecular Plant Sciences)

Atherosclerosis 2.0: From Molecular Mechanisms, Pathophysiology to Novel Therapeutic Approaches

edited by

Antonio Barbato

submission deadline 20 Nov 2024 | 8 articles | Viewed by 13242 | Submission Open

Keywords: atherosclerosis; cardiovascular risk; arterial stiffness; blood pressure; vitamin D; miRNA; inflammation

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Lysophosphatidic Acid Signaling in Health and Disease

edited by

Wei-Min Chen

and

Hsinyu Lee

submission deadline 20 Nov 2024 | 8 articles | Viewed by 13090 | Submission Open

(This special issue belongs to the Section Biochemistry)

Biomaterials: From Design, Synthesis and Characterization to Application

edited by

Tao Sun

and

Xujin Bao

submission deadline 20 Nov 2024 | 6 articles | Viewed by 12999 | Submission Open

Keywords: biomaterials; synthesis; characterization; therapeutics; diagnosis

(This special issue belongs to the Section Materials Science)

Pathogenesis and Therapy of Oral Carcinogenesis, 2nd Edition

edited by

Marko Tarle

and

Ivica Lukšić

submission deadline 20 Nov 2024 | 7 articles | Viewed by 12980 | Submission Open

Keywords: oral cancer; oral premalignant disorders; tumor microenvironment; molecular biomarkers; targeted therapy; oral tumorigenesis

(This special issue belongs to the Section Molecular Oncology)

Neuromodulatory Effects of Serotonin

edited by

Yasemin M. Akay

submission deadline 20 Nov 2024 | 7 articles | Viewed by 11767 | Submission Open

Keywords: neuromodulation; Serotonin; pain research; cognition; emotions; depression; anxiety; GBM

(This special issue belongs to the Section Molecular Neurobiology)

Molecular Studies of Natural Compounds and Plant Extracts—2nd Edition

edited by

Diamanto Lazari

and

Hsinjung Ho

submission deadline 20 Nov 2024 | 9 articles | Viewed by 11718 | Submission Open

Keywords: bioactive substances; plant extracts; polysaccharides; flavonoids; alkaloids; saponins; terpenes; phenolic acids; volatile oils; antioxidant/anti-inflammatory/anti-cancer; blood pressure lowering; blood sugar lowering; antibacterial; antiviral; antiallergic

(This special issue belongs to the Section Biochemistry)

Pathophysiology to Novel Therapeutic Approaches for Leukemia

edited by

Mauro Di Ianni

submission deadline 20 Nov 2024 | 5 articles | Viewed by 11053 | Submission Open

Keywords: acute myeloid leukemia; acute lymphoblastic leukemia; molecular pathophysiology; new therapeutic approaches; immunotherapy; cellular therapy; allogenic bone marrow transplantation

(This special issue belongs to the Section Molecular Oncology)

The Microbiota-Gut-Brain Axis in Relation to Non-communicable Diseases

edited by

Diego A. Moreno

Bruno Ramos-Molina

and

Antonio J. Ruiz-Alcaraz

submission deadline 20 Nov 2024 | 4 articles | Viewed by 11047 | Submission Open

Keywords: gut– brain axis; gut microbiota; behavior; bioactive molecules; cognitive health; diabetes; in vitro models; in vivo models; hormones; intestine; obesity; probiotics; prebiotics; synbiotics

(This special issue belongs to the Section Molecular Microbiology)

Plant Phylogenomics and Genetic Diversity (2nd Edition)

edited by

Wenpan Dong

submission deadline 20 Nov 2024 | 10 articles | Viewed by 10787 | Submission Open

Keywords: plant phylogenomics; genome; gene evolution; species diversity; speciation; ecogenomics

(This special issue belongs to the Section Molecular Plant Sciences)

Resistance to Therapy in Ovarian Cancers

edited by

Serena Bonin

submission deadline 20 Nov 2024 | 3 articles | Viewed by 10545 | Submission Open

Keywords: ovarian cancers; therapy response; biomarkers; innovative drugs; drug resistance; drug metabolism; drug delivery; platinum-based chemotherapy; PARP inhibitors; intratumor heterogeneity; microenvironment; homologous recombination deficiency

(This special issue belongs to the Section Molecular Oncology)

Molecular Pharmacology of Antidepressants

edited by

Anna Tabęcka-Łonczyńska

and

Katarzyna Stachowicz

submission deadline 20 Nov 2024 | 5 articles | Viewed by 10386 | Submission Open

Keywords: depression; pharmacotherapy of depression; molecular mechanisms of depression; mood; pharmacology of depression; antidepressants; drug-drug interactions; in vitro mechanism for antidepressants; side effects of antidepressants

(This special issue belongs to the Section Molecular Pharmacology)

Advanced Therapy Medicinal Products: From Mechanism to Production

edited by

Massimiliano Petrini

submission deadline 20 Nov 2024 | 3 articles | Viewed by 10198 | Submission Open

(This special issue belongs to the Section Molecular Biology)

Parasite Biology and Host-Parasite Interactions: 2nd Edition

edited by

Michael Stear

and

Katarzyna Donskow-Lysoniewska

submission deadline 20 Nov 2024 | 7 articles | Viewed by 10158 | Submission Open

Keywords: parasite; immunity; immunomodulation; helper T cells; IgA; IgE; eosinophils; mast cells; regulatory T cells; galectin

(This special issue belongs to the Section Molecular Biology)

Molecular Mechanisms of Somatic Cell Cloning and Other Assisted Reproductive Technologies in Mammals

edited by

Marcin Samiec

and

Maria Skrzyszowska

submission deadline 20 Nov 2024 | 5 articles | Viewed by 10046 | Submission Open

Keywords: somatic cell nuclear transfer (SCNT); SCNT-based cloning; assisted reproductive technology (ART); in vitro embryo production (IVP); in vitro fertilization (IVF); intracytoplasmic sperm injection (ICSI); in vivo embryo production

(This special issue belongs to the Section Molecular Biology)

Advances in Therapeutics against Eukaryotic Pathogens

edited by

Edward D’Antonio

submission deadline 20 Nov 2024 | 6 articles | Viewed by 9904 | Submission Open

Keywords: medicinal chemistry; parasitology; pathogen; drug-target; NTD; cryptosporidia; Giardia; helminths; Leishmania; Naegleria; Plasmodium; Schistosoma; Toxoplasma; Trichomonas; Trypanosoma

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Neutrophil Extracellular Traps (NETs) in Immunity and Diseases: 2nd Edition

edited by

Jasmin Knopf

submission deadline 20 Nov 2024 | 8 articles | Viewed by 9620 | Submission Open

Keywords: neutrophils; neutrophil functions; neutrophil extracellular traps (NETs); NETs biology; NETs in autoimmune diseases; NETs in immune response; NETs in development and progression of cancer diseases; NETs in immunothrombosis; degradation of NETs

(This special issue belongs to the Section Molecular Immunology)

Valorization of Lignocellulosic Biomass

edited by

Haishun Du

Sonali Mohapatra

and

Xuejun Pan

submission deadline 20 Nov 2024 | 6 articles | Viewed by 9451 | Submission Open

Keywords: lignocellulosic biomass; biorefinery; biomass conversion; bioenergy; biofuels; bioproducts; platform chemicals; cellulose nanomaterials; lignin nanoparticles; functional materials

(This special issue belongs to the Section Materials Science)

Molecular and Cellular Mechanisms of Epilepsy—3rd Edition

edited by

Aleksey Zaitsev

submission deadline 20 Nov 2024 | 6 articles | Viewed by 9327 | Submission Open

Keywords: epilepsy; epilepsy models; epileptogenesis; preventing epilepsy; neuroinflammation; neuroprotection; synaptic plasticity; neuron– astrocyte interaction

(This special issue belongs to the Section Molecular Neurobiology)

Viral Diseases of the Respiratory System—Molecular Mechanisms and Pathogenesis 2.0

edited by

Andreas Beineke

submission deadline 20 Nov 2024 | 7 articles | Viewed by 9264 | Submission Open

Keywords: respiratory diseases; pneumonia; pneumotropic viruses; pathogenesis; host– pathogen interaction; pulmonary pathology; immunopathology; immunity; disease prevention; treatment; zoonotic diseases; antiviral therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Novel Targeted Therapies and Drugs in Cancer

edited by

Maria Teresa Vietri

submission deadline 20 Nov 2024 | 4 articles | Viewed by 8950 | Submission Open

Keywords: targeted therapies; genetic mutation; PARP inhibitors; immunotherapy; drug development; cancer molecular analysis; drug response; molecular-targeted therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Kynurenic Acid: Emerging Research Advances and Therapeutic Implications

edited by Piotr Paluszkiewicz and Monika Turska-Kozłowska

submission deadline 20 Nov 2024 | 6 articles | Viewed by 8823 | Submission Open

Keywords: kynurenic acid; kynurenine pathway; kynurenine; therapeutic use; supply and distribution

(This special issue belongs to the Section Molecular Endocrinology and Metabolism)

Focus on Bacterial Pathogens: Host Cell Defense Pathways and Innovative Therapeutic Strategies

edited by

Edyta Juszczuk-Kubiak

submission deadline 20 Nov 2024 | 4 articles | Viewed by 8727 | Submission Open

Keywords: bacterial pathogenesis and virulence factors; host immune response to bacterial infection; innate and adaptive immunity against bacterial pathogens; immune evasion strategies employed by bacterial pathogens; innovative therapeutic strategies against bacterial pathogens; antimicrobial resistance and novel treatment strategies

(This special issue belongs to the Section Molecular Microbiology)

Lung Cancers: An Update on Molecular Diagnostics and Therapy

edited by

Mariusz Chabowski

submission deadline 20 Nov 2024 | 5 articles | Viewed by 8611 | Submission Open

Keywords: lung cancer; cancer cachexia; prognosis; anti-lung cancer agents

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Toxicity Mechanism of Emerging Pollutants

edited by

Monika Naumowicz

and

Joanna Kotyńska

submission deadline 20 Nov 2024 | 7 articles | Viewed by 8561 | Submission Open

Keywords: emerging pollutant; toxicology; cancer; EDC; pesticides; microplastic; human cell lines; environment; molecular mechanisms

(This special issue belongs to the Section Molecular Toxicology)

Advances in Peripheral Nerve Regeneration

edited by

Cinzia Fabrizi

submission deadline 20 Nov 2024 | 5 articles | Viewed by 8515 | Submission Open

Keywords: peripheral nerve regeneration; schwann cells; axonal regrowth; nerve regrowth

(This special issue belongs to the Section Molecular Neurobiology)

Inflammation and Endothelial Dysfunction in Cardio-Cerebrovascular Disease

edited by

Vittoriano Della Corte

submission deadline 20 Nov 2024 | 4 articles | Viewed by 8350 | Submission Open

Keywords: endothelial dysfunction; inflammation; cytokines; atherosclerosis; arterial stiffness; stroke; myocardial infarction; cardiovascular risk; microRNA; miRNA

(This special issue belongs to the Section Molecular Immunology)

Bioactive Compounds in Cancers

edited by

Patricia M. A. Silva

Honorina Cidade

and

Hassan Bousbaa

submission deadline 20 Nov 2024 | 7 articles | Viewed by 8313 | Submission Open

Keywords: anticancer strategies; bioactive compounds; natural products; synthetic products; medicinal chemistry; drug repurposing; drug delivery systems

(This special issue belongs to the Section Bioactives and Nutraceuticals)

Immunity in Neurodegenerative Diseases: Systemic Immune Imbalance, Neuroinflammation, and Beyond

edited by

Ivana Munitic

and

Frenkel Dan

submission deadline 20 Nov 2024 | 7 articles | Viewed by 8279 | Submission Open

Keywords: neurodegeneration; CNS immunosurveillance; neuroinflammation; neuro-immune axis; glia; T cells; phagocytosis; immunomodulation; autoimmunity; immunodeficiency

(This special issue belongs to the Section Molecular Neurobiology)

Cellular and Molecular Biology of Cardiac Hypertrophy and Heart Failure: Pathogenesis, Diagnostics and Treatment

edited by

Morris Karmazyn

submission deadline 20 Nov 2024 | 5 articles | Viewed by 8093 | Submission Open

Keywords: cardiac hypertrophy; myocardial remodelling; heart failure; cellular mechanisms; molecular mechanisms

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Advances on Retinal Diseases: 2nd Edition

edited by Minzhong Yu

submission deadline 20 Nov 2024 | 6 articles | Viewed by 8083 | Submission Open

Keywords: retina; optic nerve; ocular disorder; retinal disease; genetic mutation; aging; drug side effects; novel mutations/biomarkers; signaling pathways; spectral domain optical coherence tomography; stem cell; gene therapy

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

Structural Dynamics of Macromolecules

edited by

Ki Hyun Nam

submission deadline 20 Nov 2024 | 4 articles | Viewed by 8002 | Submission Open

Keywords: Structural biology; Structural dynamics; Serial crystallography; X-ray crystallography; Cryo-EM time-resolved studies; Molecular dynamics

(This special issue belongs to the Section Molecular Biophysics)

Molecular Insight into Novel Coatings: Design, Synthesis, and Applications

edited by

Dmitry V. Mashtalyar

and

Konstantine V. Nadaraia

submission deadline 20 Nov 2024 | 3 articles | Viewed by 7722 | Submission Open

Keywords: composite coatings; protective coatings; antibacterial coatings; superhydrophobic coatings; superhydrophilic coatings; anti-icing coatings; bioactive coatings; photocatalytic coatings

(This special issue belongs to the Section Materials Science)

New Sights: Genetic Advances and Challenges in Rare Diseases

edited by

Luisa M. Botella

submission deadline 20 Nov 2024 | 5 articles | Viewed by 7569 | Submission Open

Keywords: rare diseases; cavernomas; NGS; exome/genome; epigenome; undiagnosed rare diseases; phenotype– genotype correlations; transcription regulation; biomarkers; personalized medicine; precision medicine

(This special issue belongs to the Section Molecular Genetics and Genomics)

Stress-Related Disorders and Depression: From Molecular Basis to Therapy (2nd Edition)

edited by

Irena Nalepa

and

Agnieszka Zelek-Molik

submission deadline 20 Nov 2024 | 6 articles | Viewed by 7394 | Submission Open

Keywords: psychobiology of stress; depression; posttraumatic stress disorder; anxiety disorders; animal models; biogenic monoamines; glucocorticoids; inflammation; antidepressant and anxiolytic drugs

(This special issue belongs to the Section Molecular Neurobiology)

Metal-Based Drugs and Research on Mechanisms of Action

edited by

Elena K. Beloglazkina

submission deadline 20 Nov 2024 | 3 articles | Viewed by 7272 | Submission Open

Keywords: transition metals; metal complexes; metallodrugs; drug development; synthesis; imaging agents; structure– activity ratio

(This special issue belongs to the Section Molecular Pharmacology)

New Insights into Cardiac Ion Channel Regulation 3.0

edited by

Ademuyiwa S. Aromolaran

and

Brian P. Delisle

submission deadline 20 Nov 2024 | 4 articles | Viewed by 7196 | Submission Open

(This special issue belongs to the Section Molecular Biology)

Molecular Research on Prostate Cancer

edited by

Yaser Gamallat

submission deadline 20 Nov 2024 | 6 articles | Viewed by 7044 | Submission Open

Keywords: prostate cancer; molecular biology; genomics; biomarkers; signaling pathways; precision medicine; treatment resistance; epigenetics; therapeutic targets

(This special issue belongs to the Section Molecular Pathology, Diagnostics, and Therapeutics)

New Computational Methodologies for Computer-Aided Drug Design and Chemoinformatics

edited by

Hanoch Senderowitz

submission deadline 20 Nov 2024 | 1 articles | Viewed by 7011 | Submission Open

Keywords: chemoinformatics; machine learning; data mining; quantitative structure activity relationship (QSAR); quantitative structure property relationship (QSPR); computer aided drug design (CADD); molecular descriptors; databases; chemical space; data visualization

(This special issue belongs to the Section Molecular Informatics)

Genetic Engineering in Microbial Biotechnology

edited by

Fernando Santos-Beneit

submission deadline 20 Nov 2024 | 6 articles | Viewed by 6999 | Submission Open

Keywords: white biotechnology; red biotechnology; green biotechnology; yellow biotechnology; genetic engineering; microorganisms; bacteria; enzymes; genetics; bioproducts

(This special issue belongs to the Section Molecular Microbiology)

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