Pbx/knotted 1 homeobox (Q21987886)

Homeobox domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Homeobox protein PKNOX/Meis, N-terminal domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

Homeobox KN domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

12 September 2018

1 reference

12 September 2018

DNA-binding transcription activator activity, RNA polymerase II-specific

1 reference

14 February 2019

Cohesin regulates tissue-specific expression by stabilizing highly occupied cis-regulatory modules

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding

1 reference

11 October 2018

Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity

http://www.ebi.ac.uk/QuickGO/annotations?protein=O70477&geneProductId=UniProtKB:O70477

DNA binding

Pax6 is regulated by Meis and Pbx homeoproteins during pancreatic development

6 references

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

14 February 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

14 February 2019

14 February 2019

Activin regulation of the follicle-stimulating hormone beta-subunit gene involves Smads and the TALE homeodomain proteins Pbx1 and Prep1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

14 February 2019

The PBX-regulating protein PREP1 is present in different PBX-complexed forms in mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

14 February 2019

Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

sequence-specific DNA binding

1 reference

14 February 2019

In vivo analysis of developmentally and evolutionarily dynamic protein-DNA interactions regulating transcription of the Pgk2 gene during mammalian spermatogenesis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

protein binding

3 references

14 February 2019

Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

14 February 2019

Activin regulation of the follicle-stimulating hormone beta-subunit gene involves Smads and the TALE homeodomain proteins Pbx1 and Prep1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

14 February 2019

The PBX-regulating protein PREP1 is present in different PBX-complexed forms in mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

protein heterodimerization activity

1 reference

14 February 2019

Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

DNA-binding transcription factor activity, RNA polymerase II-specific

1 reference

14 February 2019

Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

cell component

cytoplasm

1 reference

14 February 2019

Expression of Hox cofactor genes during mouse ovarian follicular development and oocyte maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

nucleus

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

4 references

14 February 2019

14 February 2019

Expression of Hox cofactor genes during mouse ovarian follicular development and oocyte maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

14 February 2019

Pax6 is regulated by Meis and Pbx homeoproteins during pancreatic development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

14 February 2019

Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

transcription regulator complex

5 references

14 February 2019

Activin regulation of the follicle-stimulating hormone beta-subunit gene involves Smads and the TALE homeodomain proteins Pbx1 and Prep1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

14 February 2019

Pax6 is regulated by Meis and Pbx homeoproteins during pancreatic development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

14 February 2019

Trimeric association of Hox and TALE homeodomain proteins mediates Hoxb2 hindbrain enhancer activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

14 February 2019

The PBX-regulating protein PREP1 is present in different PBX-complexed forms in mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

14 February 2019

Meis1 and pKnox1 bind DNA cooperatively with Pbx1 utilizing an interaction surface disrupted in oncoprotein E2a-Pbx1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

nucleoplasm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

1 reference

14 February 2019

regulation of transcription by RNA polymerase II

biological process

erythrocyte differentiation

2 references

1 reference

14 February 2019

Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

positive regulation of transcription, DNA-templated

1 reference

14 February 2019

In vivo analysis of developmentally and evolutionarily dynamic protein-DNA interactions regulating transcription of the Pgk2 gene during mammalian spermatogenesis

British Heart Foundation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

camera-type eye development

1 reference

14 February 2019

Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

T cell differentiation

1 reference

14 February 2019

Involvement of Prep1 in the alphabeta T-cell receptor T-lymphocytic potential of hematopoietic precursors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

regulation of transcription, DNA-templated

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

1 reference

14 February 2019

angiogenesis

1 reference

14 February 2019

Hypomorphic mutation of the TALE gene Prep1 (pKnox1) causes a major reduction of Pbx and Meis proteins and a pleiotropic embryonic phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

positive regulation of transcription by RNA polymerase II

1 reference

14 February 2019

The PBX-regulating protein PREP1 is present in different PBX-complexed forms in mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

transcription by RNA polymerase II

1 reference

27 March 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=O70477&geneProductId=UniProtKB:O70477

hemopoiesis

1 reference

14 February 2019

The homeodomain transcription factor Prep1 (pKnox1) is required for hematopoietic stem and progenitor cell activity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:O70477

1 reference

Homeobox KN domain

1 reference

Homeobox protein PKNOX/Meis, N-terminal

1 reference