Identification and characterization of RHEBL1, a novel member of Ras family, which activates transcriptional activities of NF-kappa B (Q24298008)

positive regulation of NF-kappaB transcription factor activity

GOA release 2020-03-11

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GOA release 2020-03-11

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1

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author name string

Yuxi Shan

2

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Xinya Chen

3

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Wenwen Tang

4

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Kuntian Luo

5

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Jun Ni

6

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Bo Wan

7

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Long Yu

Molecular Biology Reports

8

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language of work or name

English

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publication date

December 2005

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published in

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volume

32

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issue

4

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page(s)

205-14

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cites work

Rheb interacts with Raf-1 kinase and may function to integrate growth factor- and protein kinase A-dependent signals

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The regulation of AP-1 activity by mitogen-activated protein kinases

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Identification of two novel human dynein light chain genes, DNLC2A and DNLC2B, and their expression changes in hepatocellular carcinoma tissues from 68 Chinese patients

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Regulation of the cytoskeleton and cell adhesion by the Rho family GTPases in mammalian cells.

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Rheb binds tuberous sclerosis complex 2 (TSC2) and promotes S6 kinase activation in a rapamycin- and farnesylation-dependent manner

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Ral GTPases contribute to regulation of cyclin D1 through activation of NF-kappaB.

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Rheb is in a high activation state and inhibits B-Raf kinase in mammalian cells

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Di-Ras, a distinct subgroup of ras family GTPases with unique biochemical properties

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Loss of Rhb1, a Rheb-related GTPase in fission yeast, causes growth arrest with a terminal phenotype similar to that caused by nitrogen starvation.

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The Ras branch of small GTPases: Ras family members don't fall far from the tree

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Identification and characterization of two novel human SCAN domain-containing zinc finger genes ZNF396 and ZNF397.

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Enzymology and biology of CaaX protein prenylation.

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NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses

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Biochemical and functional characterizations of small GTPase Rheb and TSC2 GAP activity

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rheb, a growth factor- and synaptic activity-regulated gene, encodes a novel Ras-related protein

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Oncogenic Ras enhances NF-kappaB transcriptional activity through Raf-dependent and Raf-independent mitogen-activated protein kinase signaling pathways

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Function and regulation of ras.

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The NF-kappa B and I kappa B proteins: new discoveries and insights

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Oncogenic Ha-Ras-induced signaling activates NF-kappaB transcriptional activity, which is required for cellular transformation

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Identification of dominant negative mutants of Rheb GTPase and their use to implicate the involvement of human Rheb in the activation of p70S6K

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Rheb is a direct target of the tuberous sclerosis tumour suppressor proteins

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12 December 2020

Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb

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12 December 2020

Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2

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12 December 2020

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12 December 2020

Role of Rab GTPases in membrane traffic

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12 December 2020

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

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12 December 2020

Rig is a novel Ras-related protein and potential neural tumor suppressor

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12 December 2020

Involvement of the switch 2 domain of Ras in its interaction with guanine nucleotide exchange factors

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12 December 2020

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12 December 2020

Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling

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12 December 2020

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

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12 December 2020

Tuberous sclerosis: from tubers to mTOR.

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12 December 2020

A novel approach for expression cloning of small GTPases: identification, tissue distribution and chromosome mapping of the human homolog of rheb

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12 December 2020

Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

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12 December 2020

Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM)

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CLUSTAL W: improving the sensitivity of progressive multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice

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