Thymine DNA glycosylase specifically recognizes 5-carboxylcytosine-modified DNA (Q24305161)

protein homodimerization activity

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

Junyan Lu

3

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author name string

Liang Zhang

1

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Xingyu Lu

2

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Haihua Liang

4

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Qing Dai

5

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Guo-Liang Xu

6

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Cheng Luo

7

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Hualiang Jiang

8

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Chuan He

DNA demethylation dynamics

9

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language of work or name

English

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publication date

April 2012

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published in

Nature Chemical Biology

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volume

8

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issue

4

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page(s)

328-30

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307914

Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites

19 March 2017

1 reference

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Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

19 March 2017

1 reference

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Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

19 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3307914

Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair

19 March 2017

1 reference

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Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain

19 March 2017

1 reference

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Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

19 March 2017

1 reference

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Uracil-DNA glycosylase-DNA substrate and product structures: conformational strain promotes catalytic efficiency by coupled stereoelectronic effects

19 March 2017

1 reference

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Instability and decay of the primary structure of DNA

19 March 2017

1 reference

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Crystal structure of human thymine DNA glycosylase bound to DNA elucidates sequence-specific mismatch recognition

19 March 2017

1 reference

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Structure and specificity of the vertebrate anti-mutator uracil-DNA glycosylase SMUG1

19 March 2017

1 reference

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A nucleotide-flipping mechanism from the structure of human uracil-DNA glycosylase bound to DNA

19 March 2017

1 reference

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Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability

19 March 2017

1 reference

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Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification

19 March 2017

1 reference

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Genomic DNA methylation: the mark and its mediators

19 March 2017

1 reference

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The discovery of 5-formylcytosine in embryonic stem cell DNA.

19 March 2017

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Epigenetic reprogramming in plant and animal development

27 September 2017

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Active DNA demethylation: many roads lead to Rome.

27 September 2017

1 reference

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Excision of 5-halogenated uracils by human thymine DNA glycosylase. Robust activity for DNA contexts other than CpG.

27 September 2017

1 reference

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The intricate structural chemistry of base excision repair machinery: implications for DNA damage recognition, removal, and repair.

27 September 2017

1 reference

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A mechanistic perspective on the chemistry of DNA repair glycosylases

27 September 2017

1 reference

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Powering DNA repair through substrate electrostatic interactions

27 September 2017

1 reference

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Base excision repair initiation revealed by crystal structures and binding kinetics of human uracil-DNA glycosylase with DNA.

27 September 2017

1 reference

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Specificity of human thymine DNA glycosylase depends on N-glycosidic bond stability

27 September 2017

1 reference

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Separating substrate recognition from base hydrolysis in human thymine DNA glycosylase by mutational analysis

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FNCHEMBIO.914

21 January 2018

Identifiers

DOI

10.1038/NCHEMBIO.914

1 reference

Dimensions Publication ID

1017180430

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1 reference

1 reference

PubMed publication ID

22327402

1 reference