Nuclear CDKs drive Smad transcriptional activation and turnover in BMP and TGF-beta pathways (Q24317164)

Mothers against dpp Dmel_CG12399

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Joan Massagué Solé

13

0 references

Maria J Macias

10

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author name string

Claudio Alarcón

1

0 references

Alexia-Ileana Zaromytidou

2

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Qiaoran Xi

3

0 references

Sheng Gao

4

0 references

Jianzhong Yu

5

0 references

Sho Fujisawa

6

0 references

Afsar Barlas

7

0 references

Alexandria N Miller

8

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Katia Manova-Todorova

9

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Gopal Sapkota

11

0 references

Duojia Pan

Integrating patterning signals: Wnt/GSK3 regulates the duration of the BMP/Smad1 signal

12

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language of work or name

English

0 references

publication date

13 November 2009

0 references

published in

Cell

0 references

volume

139

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issue

4

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page(s)

757-69

0 references

cites work

1 reference

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PPM1A functions as a Smad phosphatase to terminate TGFbeta signaling

19 March 2017

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Mastermind recruits CycC:CDK8 to phosphorylate the Notch ICD and coordinate activation with turnover

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Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus

19 March 2017

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TGF-beta signal transduction

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19 March 2017

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Id genes are direct targets of bone morphogenetic protein induction in embryonic stem cells

19 March 2017

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Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1

19 March 2017

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The subcellular locations of p15(Ink4b) and p27(Kip1) coordinate their inhibitory interactions with cdk4 and cdk2

19 March 2017

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Specificity and versatility in tgf-beta signaling through Smads

7 April 2017

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7 April 2017

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BMP induction of Id proteins suppresses differentiation and sustains embryonic stem cell self-renewal in collaboration with STAT3

7 April 2017

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hippo encodes a Ste-20 family protein kinase that restricts cell proliferation and promotes apoptosis in conjunction with salvador and warts

7 April 2017

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Ubiquitin ligase Nedd4L targets activated Smad2/3 to limit TGF-beta signaling

7 April 2017

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YAP regulates neural progenitor cell number via the TEA domain transcription factor

27 September 2017

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E2F1 represses beta-catenin transcription and is antagonized by both pRB and CDK8

27 September 2017

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27 September 2017

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Genome-wide impact of the BRG1 SWI/SNF chromatin remodeler on the transforming growth factor beta transcriptional program

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27 September 2017

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Unique players in the BMP pathway: small C-terminal domain phosphatases dephosphorylate Smad1 to attenuate BMP signaling.

27 September 2017

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From cell structure to transcription: Hippo forges a new path

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Integration of IGF, FGF, and anti-BMP signals via Smad1 phosphorylation in neural induction

27 September 2017

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Nucleocytoplasmic shuttling of Smad1 conferred by its nuclear localization and nuclear export signals

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Nucleocytoplasmic shuttling of Smads 2, 3, and 4 permits sensing of TGF-beta receptor activity

27 September 2017

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Drosophila Mad binds to DNA and directly mediates activation of vestigial by Decapentaplegic

30 May 2018

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30 May 2018

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29 November 2018

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29 November 2018

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29 November 2018

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29 November 2018

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Balancing BMP Signaling through Integrated Inputs into the Smad1 Linker

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19914168

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

In vitro and in vivo antitumor properties of the cyclin dependent kinase inhibitor CYC202 (R-roscovitine)

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19914168

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2009.09.035

1 reference

1 reference

1 reference

PubMed publication ID

19914168

1 reference