The anti-angiogenic agent fumagillin covalently binds and inhibits the methionine aminopeptidase, MetAP-2 (Q24684014)

2

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M Q Wang

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J J Wen

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W G Bornmann

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C M Crews

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

10 June 1997

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published in

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volume

94

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issue

12

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page(s)

6099-103

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cites work

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Amino-terminal protein processing in Saccharomyces cerevisiae is an essential function that requires two distinct methionine aminopeptidases

7 April 2017

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A mammalian histone deacetylase related to the yeast transcriptional regulator Rpd3p

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Characteristics of the eukaryotic initiation factor 2 associated 67-kDa polypeptide

7 April 2017

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In vivo half-life of a protein is a function of its amino-terminal residue

7 April 2017

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Inhibition of vascular endothelial growth factor-induced angiogenesis suppresses tumour growth in vivo

7 April 2017

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A eukaryotic translation initiation factor 2-associated 67 kDa glycoprotein partially reverses protein synthesis inhibition by activated double-stranded RNA-dependent protein kinase in intact cells

7 April 2017

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Cloning and characterization of complementary DNA encoding the eukaryotic initiation factor 2-associated 67-kDa protein (p67).

28 September 2017

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Molecular cloning of a human complementary DNA encoding an initiation factor 2-associated protein (p67).

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Angiogenesis inhibition: a review

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The implications of angiogenesis for the biology and therapy of cancer metastasis

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Roles of a 67-kDa polypeptide in reversal of protein synthesis inhibition in heme-deficient reticulocyte lysate

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Inhibition of angiogenesis

28 September 2017

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The eukaryotic initiation factor 2-associated 67-kDa polypeptide (p67) plays a critical role in regulation of protein synthesis initiation in animal cells.

28 September 2017

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AGM-1470 inhibits the growth of human glioblastoma cells in vitro and in vivo

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Angiogenesis inhibitor TNP-470 (AGM-1470) potently inhibits the tumor growth of hormone-independent human breast and prostate carcinoma cell lines

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Isolation and characterization of the methionine aminopeptidase from porcine liver responsible for the co-translational processing of proteins

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The effect of AGM-1470 in an improved intracranial 9L gliosarcoma rat model

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Iodinated fatty acids as probes for myristate processing and function. Incorporation into pp60v-src

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12 December 2020

The combination of antiangiogenic agents to inhibit primary tumor growth and metastasis

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12 December 2020

A fumagillin derivative angiogenesis inhibitor, AGM-1470, inhibits activation of cyclin-dependent kinases and phosphorylation of retinoblastoma gene product but not protein tyrosyl phosphorylation or protooncogene expression in vascular endothelial

1 reference

12 December 2020

N-myristoylation of the rod outer segment G protein, transducin, in cultured retinas

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12 December 2020

The angiogenesis inhibitor AGM-1470 selectively increases E-selectin

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12 December 2020

Methionine aminopeptidase-1: the MAP of the mitochondrion?

1 reference

12 December 2020

1 reference

12 December 2020

Chemical modification of fumagillin. II. 6-Amino-6-deoxyfumagillol and its derivatives

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12 December 2020

Identifiers

DOI

10.1073/PNAS.94.12.6099

1 reference

release_tndhxwkmlnds3ngvknartlvfum

0 references

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/tndhxwkmlnds3ngvknartlvfum

24 November 2022

mapped directly with Wikidata item

1357872

1 reference

1 reference

1357872

PubMed publication ID

9177176

1 reference