The CYP4A isoforms hydroxylate epoxyeicosatrienoic acids to form high affinity peroxisome proliferator-activated receptor ligands (Q28578924)

31 January 2017

title

The CYP4A isoforms hydroxylate epoxyeicosatrienoic acids to form high affinity peroxisome proliferator-activated receptor ligands (English)

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31 January 2017

L. Ashley Cowart

1

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31 January 2017

Shouzuo Wei

2

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31 January 2017

Mei-Hui Hsu

3

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31 January 2017

Eric F. Johnson

4

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31 January 2017

Murali U. Krishna

5

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31 January 2017

John R. Falck

6

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31 January 2017

Jorge H. Capdevila

7

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31 January 2017

language of work or name

English

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publication date

20 September 2002

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Journal of Biological Chemistry

31 January 2017

published in

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31 January 2017

volume

277

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31 January 2017

issue

38

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31 January 2017

page(s)

35105–35112

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The rat clofibrate-inducible CYP4A subfamily. II. cDNA sequence of IVA3, mapping of the Cyp4a locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes

31 January 2017

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Cloning, sequencing, and cDNA-directed expression of the rat renal CYP4A2: arachidonic acid omega-hydroxylation and 11,12-epoxidation by CYP4A2 protein

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Targeted disruption of the alpha isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators

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P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR.

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Peroxisome proliferator-activated receptor alpha controls the hepatic CYP4A induction adaptive response to starvation and diabetes

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The CYP P450 arachidonic acid monooxygenases: from cell signaling to blood pressure regulation

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Cytochrome P450 metabolites of arachidonic acid in the control of renal function

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Pathways of epoxyeicosatrienoic acid metabolism in endothelial cells. Implications for the vascular effects of soluble epoxide hydrolase inhibition

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Peroxisome proliferator-activated receptors: from genes to physiology

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A carboxyl-terminal extension of the zinc finger domain contributes to the specificity and polarity of peroxisome proliferator-activated receptor DNA binding

21 January 2018

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Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reaction

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Alterations in the regulation of androgen-sensitive Cyp 4a monooxygenases cause hypertension

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Identification of CYP4F8 in human seminal vesicles as a prominent 19-hydroxylase of prostaglandin endoperoxides

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Cytochrome P450 CYP2J9, a new mouse arachidonic acid omega-1 hydroxylase predominantly expressed in brain

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Arachidonic acid epoxygenase: structural characterization and quantification of epoxyeicosatrienoates in plasma

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Down-regulation of cytochrome P450 2C family members and positive acute-phase response gene expression by peroxisome proliferator chemicals

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Soluble epoxide hydrolase regulates hydrolysis of vasoactive epoxyeicosatrienoic acids

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An antidiabetic thiazolidinedione is a high affinity ligand for peroxisome proliferator-activated receptor gamma (PPAR gamma)

21 January 2018

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Differential activation of peroxisome proliferator-activated receptors by eicosanoids.

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15-Deoxy-delta 12, 14-prostaglandin J2 is a ligand for the adipocyte determination factor PPAR gamma

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A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation

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Hypolipidemic drugs, polyunsaturated fatty acids, and eicosanoids are ligands for peroxisome proliferator-activated receptors alpha and delta

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cis -Parinaric acid is a ligand for the human peroxisome proliferator activated receptor γ: development of a novel spectrophotometric assay for the discovery of PPARγ ligands

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21 January 2018

Identifiers

DOI

10.1074/JBC.M201575200

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017

1 reference

Consolidated OpenCitations Corpus – April 2017