Does the ribosome translate cancer? (Q29618775)

Europe PubMed Central

title

Does the ribosome translate cancer? (English)

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30 April 2017

author name string

Ruggero D

series ordinal

1

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30 April 2017

Pandolfi PP

series ordinal

2

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30 April 2017

language of work or name

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30 April 2017

publication date

March 2003

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30 April 2017

published in

Nature Reviews Cancer

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30 April 2017

volume

3

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issue

3

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30 April 2017

page(s)

179-92

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The nucleoli of cultured human lymphocytes. I. Nucleolar morphology in relation to transformation and the DNA cycle

30 April 2017

cites work

1 reference

X-linked dyskeratosis congenita is caused by mutations in a highly conserved gene with putative nucleolar functions

31 March 2020

1 reference

Dyskeratosis congenita and cancer in mice deficient in ribosomal RNA modification

31 March 2020

1 reference

The gene encoding ribosomal protein S19 is mutated in Diamond-Blackfan anaemia

31 March 2020

1 reference

G1 events and regulation of cell proliferation

31 March 2020

1 reference

Cell-cycle-dependent translational control

31 March 2020

1 reference

Regulation of Mammalian Ribosomal Gene Transcription by RNA Polymerase I

31 March 2020

1 reference

Amino acid starvation affects the initiation frequency of nucleolar RNA polymerase

31 March 2020

1 reference

Coordinate control of syntheses of ribosomal ribonucleic acid and ribosomal proteins during nutritional shift-up in Saccharomyces cerevisiae

31 March 2020

1 reference

Cell cycle-dependent regulation of RNA polymerase I transcription: the nucleolar transcription factor UBF is inactive in mitosis and early G1.

31 March 2020

1 reference

Activity of RNA polymerase I transcription factor UBF blocked by Rb gene product

31 March 2020

1 reference

Coactivator and promoter-selective properties of RNA polymerase I TAFs

31 March 2020

1 reference

Functional Cooperativity Between Transcription Factors UBF1 and SL1 Mediates Human Ribosomal RNA Synthesis

31 March 2020

1 reference

Nucleolar transcription factor hUBF contains a DNA-binding motif with homology to HMG proteins

31 March 2020

1 reference

Phosphorylation by G1-specific cdk-cyclin complexes activates the nucleolar transcription factor UBF.

31 March 2020

1 reference

Phosphorylation of the rRNA transcription factor upstream binding factor promotes its association with TATA binding protein

31 March 2020

1 reference

Recruitment of TATA-binding protein-TAFI complex SL1 to the human ribosomal DNA promoter is mediated by the carboxy-terminal activation domain of upstream binding factor (UBF) and is regulated by UBF phosphorylation

31 March 2020

1 reference

Phosphorylation of UBF at serine 388 is required for interaction with RNA polymerase I and activation of rDNA transcription

31 March 2020

1 reference

An immediate response of ribosomal transcription to growth factor stimulation in mammals is mediated by ERK phosphorylation of UBF

31 March 2020

1 reference

Activation of mammalian ribosomal gene transcription requires phosphorylation of the nucleolar transcription factor UBF

31 March 2020

1 reference

Mammary hyperplasia and carcinoma in MMTV-cyclin D1 transgenic mice

31 March 2020

1 reference

Induction of mammary gland hyperplasia and carcinomas in transgenic mice expressing human cyclin E

31 March 2020

1 reference

Rrn3 phosphorylation is a regulatory checkpoint for ribosome biogenesis

31 March 2020

1 reference

Multiple interactions between RNA polymerase I, TIF-IA and TAF(I) subunits regulate preinitiation complex assembly at the ribosomal gene promoter

31 March 2020

1 reference

The retinoblastoma tumour suppressor in development and cancer

31 March 2020

1 reference

Mechanism of repression of RNA polymerase I transcription by the retinoblastoma protein

31 March 2020

1 reference

Rb and p130 regulate RNA polymerase I transcription: Rb disrupts the interaction between UBF and SL-1

31 March 2020

1 reference

Overlapping functions of the pRb family in the regulation of rRNA synthesis

31 March 2020

1 reference

RNA polymerase I transcription in confluent cells: Rb downregulates rDNA transcription during confluence-induced cell cycle arrest

31 March 2020

1 reference

Repression of RNA polymerase I transcription by the tumor suppressor p53

31 March 2020

1 reference

Repression of RNA polymerase III transcription by the retinoblastoma protein

31 March 2020

1 reference

Retinoblastoma protein disrupts interactions required for RNA polymerase III transcription

31 March 2020

1 reference

p53 is a general repressor of RNA polymerase III transcription

31 March 2020

1 reference

A single amino acid substitution results in a retinoblastoma protein defective in phosphorylation and oncoprotein binding

31 March 2020

1 reference

Transcription by RNA polymerases I and III: a potential link between cell growth, protein synthesis and the retinoblastoma protein

31 March 2020

1 reference

Changes in RNA in relation to growth of the fibroblast. III. Posttranscriptional regulation of mRNA formation in resting and growing cells

31 March 2020

1 reference

The effect of protein degradation on cellular growth characteristics

31 March 2020

1 reference

ncl-1 is required for the regulation of cell size and ribosomal RNA synthesis in Caenorhabditis elegans

31 March 2020

1 reference

31 March 2020

1 reference

RNA binding strategies of ribosomal proteins

31 March 2020

1 reference

31 March 2020

The ribosome in focus

1 reference

Ribosome structure and the mechanism of translation

31 March 2020

1 reference

Gene expression profiles in normal and cancer cells

31 March 2020

1 reference

Broad patterns of gene expression revealed by clustering analysis of tumor and normal colon tissues probed by oligonucleotide arrays

31 March 2020

1 reference

A complete map of the human ribosomal protein genes: assignment of 80 genes to the cytogenetic map and implications for human disorders

31 March 2020

1 reference

Ribosomal proteins sustain morphology, function and phenotype in acute myeloid leukemia blasts

31 March 2020

1 reference

The economics of ribosome biosynthesis in yeast

31 March 2020

1 reference

Depletion of Saccharomyces cerevisiae ribosomal protein L16 causes a decrease in 60S ribosomal subunits and formation of half-mer polyribosomes

31 March 2020

1 reference

A Drosophila Minute gene encodes a ribosomal protein.

31 March 2020

1 reference

Proliferation, but not growth, blocked by conditional deletion of 40S ribosomal protein S6

31 March 2020

1 reference

Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins

31 March 2020

1 reference

Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family

31 March 2020

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Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

31 March 2020

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Protein elongation factor EEF1A2 is a putative oncogene in ovarian cancer

31 March 2020

1 reference

Multiple phosphorylation of ribosomal protein S6 during transition of quiescent 3T3 cells into early G1, and cellular compartmentalization of the phosphate donor

31 March 2020

1 reference

Drosophila S6 kinase: a regulator of cell size

31 March 2020

1 reference

Disruption of the p70(s6k)/p85(s6k) gene reveals a small mouse phenotype and a new functional S6 kinase

31 March 2020

1 reference

Targeted disruption of p70(s6k) defines its role in protein synthesis and rapamycin sensitivity

31 March 2020

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Transduction of growth or mitogenic signals into translational activation of TOP mRNAs is fully reliant on the phosphatidylinositol 3-kinase-mediated pathway but requires neither S6K1 nor rpS6 phosphorylation

31 March 2020

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Altered cellular responses by varying expression of a ribosomal protein gene: sequential coordination of enhancement and suppression of ribosomal protein S3a gene expression induces apoptosis

31 March 2020

1 reference

Implication of mammalian ribosomal protein S3 in the processing of DNA damage

31 March 2020

1 reference

Translocations involving c-myc and c-myc function

31 March 2020

1 reference

Expression analysis with oligonucleotide microarrays reveals that MYC regulates genes involved in growth, cell cycle, signaling, and adhesion

31 March 2020

1 reference

N-myc enhances the expression of a large set of genes functioning in ribosome biogenesis and protein synthesis

31 March 2020

1 reference

Characterization of the c-MYC-regulated transcriptome by SAGE: identification and analysis of c-MYC target genes

31 March 2020

1 reference

c-Myc enhances protein synthesis and cell size during B lymphocyte development

31 March 2020

1 reference

Induction of ribosomal genes and hepatocyte hypertrophy by adenovirus-mediated expression of c-Myc in vivo

31 March 2020

1 reference

Modulation of T-lymphocyte development, growth and cell size by the Myc antagonist and transcriptional repressor Mad1.

31 March 2020

1 reference

The role of c-myc in cellular growth control

31 March 2020

1 reference

Regulation of cell size in growth, development and human disease: PI3K, PKB and S6K.

31 March 2020

1 reference

Pten is essential for embryonic development and tumour suppression

31 March 2020

1 reference

Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse

31 March 2020

1 reference

PI 3-kinase, mTOR, protein synthesis and cancer

31 March 2020

1 reference

PTEN function in mammalian cell size regulation

31 March 2020

1 reference

The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-trisphosphate

31 March 2020

1 reference

The lipid phosphatase activity of PTEN is critical for its tumor supressor function

31 March 2020

1 reference

Control of p70 s6 kinase by kinase activity of FRAP in vivo

31 March 2020

1 reference

RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

31 March 2020

1 reference

Immunopurified mammalian target of rapamycin phosphorylates and activates p70 S6 kinase alpha in vitro

31 March 2020

1 reference

Interaction of RAFT1 with gephyrin required for rapamycin-sensitive signaling

31 March 2020

1 reference

Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

31 March 2020

1 reference

An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice

31 March 2020

1 reference

4E-BP1, a repressor of mRNA translation, is phosphorylated and inactivated by the Akt(PKB) signaling pathway

31 March 2020

1 reference

Phosphorylation and activation of p70s6k by PDK1

31 March 2020

1 reference

Mutation of Pten/Mmac1 in mice causes neoplasia in multiple organ systems

31 March 2020

1 reference

High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice

31 March 2020

1 reference

A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells

31 March 2020

1 reference

TSC2 is phosphorylated and inhibited by Akt and suppresses mTOR signalling

31 March 2020

1 reference

Tsc tumour suppressor proteins antagonize amino-acid-TOR signalling

31 March 2020

1 reference

Tuberous sclerosis complex-1 and -2 gene products function together to inhibit mammalian target of rapamycin (mTOR)-mediated downstream signaling

31 March 2020

1 reference

Lethality of Drosophila lacking TSC tumor suppressor function rescued by reducing dS6K signaling

31 March 2020

1 reference

Tuberin regulates p70 S6 kinase activation and ribosomal protein S6 phosphorylation. A role for the TSC2 tumor suppressor gene in pulmonary lymphangioleiomyomatosis (LAM)

31 March 2020

1 reference

Tuberous sclerosis complex tumor suppressor-mediated S6 kinase inhibition by phosphatidylinositide-3-OH kinase is mTOR independent

31 March 2020

1 reference

Malignant transformation by a eukaryotic initiation factor subunit that binds to mRNA 5' cap

31 March 2020

1 reference

eIF4E expression in tumors: its possible role in progression of malignancies

31 March 2020

1 reference

eIF4 initiation factors: effectors of mRNA recruitment to ribosomes and regulators of translation

31 March 2020

1 reference

Small nucleolar RNAs direct site-specific synthesis of pseudouridine in ribosomal RNA

31 March 2020

1 reference

The box H + ACA snoRNAs carry Cbf5p, the putative rRNA pseudouridine synthase

31 March 2020

1 reference

Dyskeratosis congenita in all its forms

31 March 2020

1 reference

minifly, a Drosophila gene required for ribosome biogenesis

31 March 2020

1 reference

Point mutations in yeast CBF5 can abolish in vivo pseudouridylation of rRNA

31 March 2020

1 reference

A telomerase component is defective in the human disease dyskeratosis congenita

31 March 2020

1 reference

Longevity, Stress Response, and Cancer in Aging Telomerase-Deficient Mice

31 March 2020

1 reference

rRNA modifications and ribosome function

31 March 2020

1 reference

ELAV/Hu proteins inhibit p27 translation via an IRES element in the p27 5'UTR.

31 March 2020

1 reference

Identification and characterization of a novel cell cycle-regulated internal ribosome entry site

31 March 2020

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Cocrystal structure of a tRNA Psi55 pseudouridine synthase: nucleotide flipping by an RNA-modifying enzyme

31 March 2020

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Irresistible IRES. Attracting the translation machinery to internal ribosome entry sites

31 March 2020

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31 March 2020

Diamond-Blackfan anemia

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Translational control of growth factor and proto-oncogene expression

31 March 2020

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Cell cycle-regulated modification of the ribosome by a variant multiubiquitin chain

31 March 2020

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Bop1 is a mouse WD40 repeat nucleolar protein involved in 28S and 5. 8S RRNA processing and 60S ribosome biogenesis

31 March 2020

1 reference

Evidence of p53-dependent cross-talk between ribosome biogenesis and the cell cycle: effects of nucleolar protein Bop1 on G(1)/S transition

31 March 2020

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The rapamycin-sensitive signal transduction pathway as a target for cancer therapy

31 March 2020

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RNA-guided nucleotide modification of ribosomal and other RNAs

31 March 2020

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Identification of the tuberous sclerosis complex-2 tumor suppressor gene product tuberin as a target of the phosphoinositide 3-kinase/akt pathway

31 March 2020

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Akt regulates growth by directly phosphorylating Tsc2

31 March 2020

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12612653

31 March 2020

Identifiers

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30 April 2017

Consolidated OpenCitations Corpus – April 2017

Dimensions Publication ID

1051142121

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Consolidated OpenCitations Corpus – April 2017

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/esummary.fcgi?db=pubmed&retmode=json&id=12612653

PubMed publication ID

2 references

30 April 2017

Consolidated OpenCitations Corpus – April 2017