Bis-acridines as lead antiparasitic agents: structure-activity analysis of a discrete compound library in vitro (Q33279371)

25 July 2017

title

Bis-acridines as lead antiparasitic agents: structure-activity analysis of a discrete compound library in vitro (English)

1 reference

25 July 2017

Deirdre Walshe

5

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Aaron T Fafarman

Aaron T Fafarman

9

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Anjan Debnath

Anjan Debnath

6

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Alicia Ponte-sucre

Alicia Ponte-Sucre

15

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Tanja Schirmeister

Tanja Schirmeister

16

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Dietmar Steverding

Dietmar Steverding

2

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Alan Fairlamb

Alan H Fairlamb

18

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Fred E Cohen

19

Fred E Cohen

1 reference

25 July 2017

20

James H McKerrow

1 reference

25 July 2017

14

Heidrun Moll

1 reference

25 July 2017

17

Ahilan Saravanamuthu

1 reference

25 July 2017

Conor R Caffrey

1

1 reference

25 July 2017

Ryan K Swenerton

3

1 reference

25 July 2017

Ben Kelly

4

1 reference

25 July 2017

Yuan-Min Zhou

7

1 reference

25 July 2017

Patricia S Doyle

8

1 reference

25 July 2017

Julie A Zorn

10

1 reference

25 July 2017

Kirkwood M Land

11

1 reference

25 July 2017

Jessica Beauchene

12

1 reference

25 July 2017

Kimberly Schreiber

13

1 reference

25 July 2017

Jennifer L Weisman

21

1 reference

25 July 2017

Barnaby C H May

22

1 reference

25 July 2017

language of work or name

English

0 references

publication date

19 March 2007

1 reference

Antimicrobial Agents and Chemotherapy

25 July 2017

published in

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25 July 2017

volume

51

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25 July 2017

issue

6

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25 July 2017

page(s)

2164-2172

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Waterborne infectious diseases--could they be consigned to history?

25 July 2017

cites work

1 reference

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14 July 2018

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14 July 2018

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Malaria: burden of disease

14 July 2018

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Trypanocidal activities of trileucine methyl vinyl sulfone proteasome inhibitors.

14 July 2018

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Rational design, synthesis, and biological evaluation of bis(pyrimido[5,6,1-de]acridines) and bis(pyrazolo[3,4,5-kl]acridine-5-carboxamides) as new anticancer agents

14 July 2018

1 reference

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Two interacting binding sites for quinacrine derivatives in the active site of trypanothione reductase: a template for drug design

14 July 2018

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Antimalarial 9-anilinoacridine compounds directed at hematin

14 July 2018

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Treatment perspectives for human African trypanosomiasis

14 July 2018

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Potent inhibition of scrapie prion replication in cultured cells by bis-acridines

14 July 2018

1 reference

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In vitro activities of 7-substituted 9-chloro and 9-amino-2-methoxyacridines and their bis- and tetra-acridine complexes against Leishmania infantum

14 July 2018

1 reference

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Antimalarial in-vivo activity of bis(9-amino-6-chloro-2-methoxyacridines).

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891397

Antimalarial, antitrypanosomal, and antileishmanial activities and cytotoxicity of bis(9-amino-6-chloro-2-methoxyacridines): influence of the linker

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891397

Structure-function relationships in aminoquinolines: effect of amino and chloro groups on quinoline-hematin complex formation, inhibition of beta-hematin formation, and antiplasmodial activity.

14 July 2018

1 reference

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Cysteine protease inhibitors cure an experimental Trypanosoma cruzi infection

14 July 2018

1 reference

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Leishmania sp.: growth and survival are impaired by ion channel blockers

14 July 2018

1 reference

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Structure-activity relationships for the antileishmanial and antitrypanosomal activities of 1'-substituted 9-anilinoacridines

14 July 2018

1 reference

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On the molecular mechanism of chloroquine's antimalarial action

14 July 2018

1 reference

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A comparison of three methods of estimating EC50 in studies of drug resistance of malaria parasites

14 July 2018

1 reference

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Site-directed mutagenesis of the redox-active cysteines of Trypanosoma cruzi trypanothione reductase.

14 July 2018

1 reference

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In vitro cloning of animal-infective bloodstream forms of Trypanosoma brucei

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891397

Antimalarial and antischistosomal effects of proximal hydrazine and hydroxylamine analogs of chloroquine and quinacrine

14 July 2018

1 reference

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Cultivation in a semi-defined medium of animal infective forms of Trypanosoma brucei, T. equiperdum, T. evansi, T. rhodesiense and T. gambiense

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891397

Schistosoma mansoni and S. japonicum: comparison of levels of ultraviolet irradiation for vaccination of mice with cercariae

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891397

Subcellular distribution of trypanothione reductase in bloodstream and procyclic forms of Trypanosoma brucei.

14 July 2018

1 reference

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Bisquinolines. 1. N,N-bis(7-chloroquinolin-4-yl)alkanediamines with potential against chloroquine-resistant malaria

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891397

Metabolism and functions of trypanothione in the Kinetoplastida

14 July 2018

1 reference

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Cytotoxicity of acridine compounds for Leishmania promastigotes in vitro

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891397

Assay Conditions and the Demonstration of Nitroimidazole Resistance in Tritrichomonas foetus

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891397

Equilibrium constants for the binding of an homologous series of monofunctional and bifunctional intercalating diacridines to calf thymus DNA

14 July 2018

1 reference

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A new medium for the axenic cultivation of Entamoeba histolytica and other Entamoeba

14 July 2018

1 reference

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DNA polyintercalating drugs: DNA binding of diacridine derivatives

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891397

Design, synthesis, and biological properties of new bis(acridine-4-carboxamides) as anticancer agents

14 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891397

In vitro effect of alkaloids on bloodstream forms of Trypanosoma brucei and T. congolense

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891397

Targeted gene deletion of Leishmania major genes encoding developmental stage-specific leishmanolysin (GP63).

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891397

Trypanosoma cruzi: possible control of parasite transmission by blood transfusion using amphiphilic cationic drugs

31 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1891397

The infection of laboratory hosts with cercariae of Schistosoma mansoni and the recovery of the adult worms

10 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17371810

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cultivation of Schistosoma mansoni In vitro. I. Establishment of Cultures from Cercariae and Development until Pairing

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17371810

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1128/AAC.01418-06

1 reference

25 July 2017

1 reference

25 July 2017

1 reference