Affinity-based selection of regulatory T cells occurs independent of agonist-mediated induction of Foxp3 expression (Q33639952)

28 July 2017

title

Affinity-based selection of regulatory T cells occurs independent of agonist-mediated induction of Foxp3 expression (English)

1 reference

28 July 2017

Lance M Relland

1

1 reference

28 July 2017

Manoj K Mishra

2

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28 July 2017

Dipica Haribhai

3

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28 July 2017

Brandon Edwards

4

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28 July 2017

Jennifer Ziegelbauer

5

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28 July 2017

Calvin B Williams

6

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28 July 2017

language of work or name

English

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publication date

1 February 2009

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28 July 2017

published in

Journal of Immunology

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28 July 2017

volume

182

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28 July 2017

issue

3

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28 July 2017

page(s)

1341-1350

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Differentiation of regulatory Foxp3+ T cells in the thymic cortex

28 July 2017

cites work

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21 June 2018

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Src-like adaptor protein down-regulates T cell receptor (TCR)-CD3 expression by targeting TCRzeta for degradation

21 June 2018

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21 June 2018

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21 June 2018

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FOXP3 acts as a rheostat of the immune response

21 June 2018

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Aire regulates negative selection of organ-specific T cells

21 June 2018

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Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome

21 June 2018

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21 June 2018

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

21 June 2018

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X-linked neonatal diabetes mellitus, enteropathy and endocrinopathy syndrome is the human equivalent of mouse scurfy

21 June 2018

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JM2, encoding a fork head-related protein, is mutated in X-linked autoimmunity-allergic disregulation syndrome

21 June 2018

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The third function of the thymus.

21 June 2018

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A kinetic threshold between negative and positive selection based on the longevity of the T cell receptor-ligand complex

21 June 2018

1 reference

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Thymus and autoimmunity: production of CD25+CD4+ naturally anergic and suppressive T cells as a key function of the thymus in maintaining immunologic self-tolerance

21 June 2018

1 reference

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In vivo expression of a TCR antagonist: T cells escape central tolerance but are antagonized in the periphery

21 June 2018

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Peripheral T cell survival requires continual ligation of the T cell receptor to major histocompatibility complex-encoded molecules

21 June 2018

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Structural basis for T cell recognition of altered peptide ligands: a single T cell receptor can productively recognize a large continuum of related ligands

21 June 2018

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T cell receptor antagonist peptides induce positive selection

21 June 2018

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Crosstalk in the mouse thymus

21 June 2018

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Selective events in T cell development

21 June 2018

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Negative selection of CD4+ CD8+ thymocytes by T-cell receptor peptide antagonists

21 June 2018

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Immunologic self-tolerance maintained by activated T cells expressing IL-2 receptor alpha-chains (CD25). Breakdown of a single mechanism of self-tolerance causes various autoimmune diseases

21 June 2018

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In vivo and in vitro clonal deletion of double-positive thymocytes

21 June 2018

1 reference

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Regulatory T cell development in the absence of functional Foxp3.

21 June 2018

1 reference

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The cellular mechanism of Aire control of T cell tolerance.

30 October 2018

1 reference

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CD4+ CD25+ regulatory T cell repertoire formation in response to varying expression of a neo-self-antigen

30 October 2018

1 reference

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A role for TCR affinity in regulating naive T cell homeostasis.

30 October 2018

1 reference

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A threshold for central T cell tolerance to an inducible serum protein

30 October 2018

1 reference

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Anergy and suppression regulate CD4(+) T cell responses to a self peptide.

30 October 2018

1 reference

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TCR transgenic mice in which usage of transgenic alpha- and beta-chains is highly dependent on the level of selecting ligand.

30 October 2018

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Expression of the alpha beta T-cell receptor is necessary for the generation of the thymic medulla

30 October 2018

1 reference

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Evidence for a differential avidity model of T cell selection in the thymus

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818884

Developmental control point in induction of thymic cortex regulated by a subpopulation of prothymocytes.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818884

An X-linked syndrome of diarrhea, polyendocrinopathy, and fatal infection in infancy.

30 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2818884

Foxp3-dependent programme of regulatory T-cell differentiation

30 October 2018

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12 December 2020

Regulatory T-cell functions are subverted and converted owing to attenuated Foxp3 expression

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12 December 2020

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12 December 2020

Positive and negative selection in Basel

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12 December 2020

Stepwise development of thymic microenvironments in vivo is regulated by thymocyte subsets

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12 December 2020

Ligand-specific selection of MHC class II-restricted thymocytes in fetal thymic organ culture

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12 December 2020

Thymic selection of CD4+CD25+ regulatory T cells induced by an agonist self-peptide

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12 December 2020

CD8+ T lymphocytes in double alpha beta TCR transgenic mice. II. Competitive fitness of dual alpha beta TCR CD8+ T lymphocytes in the peripheral pools

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12 December 2020

Generation of CD4(+)CD25(+) regulatory T cells from autoreactive T cells simultaneously with their negative selection in the thymus and from nonautoreactive T cells by endogenous TCR expression

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12 December 2020

T cell fitness determined by signal strength

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12 December 2020

Ligand thresholds at different stages of T cell development

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12 December 2020

Lower receptor avidity required for thymic clonal deletion than for effector T-cell function

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12 December 2020

Disorganization and restoration of thymic medullary epithelial cells in T cell receptor-negative scid mice: evidence that receptor-bearing lymphocytes influence maturation of the thymic microenvironment

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12 December 2020

Positive and negative thymocyte selection induced by different concentrations of a single peptide

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12 December 2020

The Role of Thymocytes in Regulating Thymic Epithelial Cell Growth and Function

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12 December 2020

Dual T cell receptor T cells have a decreased sensitivity to physiological ligands due to reduced density of each T cell receptor

1 reference

12 December 2020

Development of peptide-selected CD8 T cells in fetal thymic organ culture occurs via the conventional pathway

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12 December 2020

High- and low-potency ligands with similar affinities for the TCR: the importance of kinetics in TCR signaling

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12 December 2020

Thymic microenvironments, 3-D versus 2-D?

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12 December 2020

Cutting edge: negative selection of immature thymocytes by a few peptide-MHC complexes: differential sensitivity of immature and mature T cells

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12 December 2020

Limiting TCR expression leads to quantitative but not qualitative changes in thymic selection

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12 December 2020

Ontogeny and regulation of IL-7-expressing thymic epithelial cells

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12 December 2020

Origin and T cell receptor diversity of Foxp3+CD4+CD25+ T cells

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12 December 2020

10.4049/JIMMUNOL.182.3.1341

Identifiers

DOI

1 reference

28 July 2017

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28 July 2017

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