EGFRvIII and c-Met pathway inhibitors synergize against PTEN-null/EGFRvIII+ glioblastoma xenografts. (Q33756853)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19584231%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

title

EGFRvIII and c-Met pathway inhibitors synergize against PTEN-null/EGFRvIII+ glioblastoma xenografts (English)

1 reference

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2 February 2020

1 reference

1 reference

2

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2 February 2020

7

Martin G Pomper

1 reference

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2 February 2020

author name string

Bachchu Lal

1

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2 February 2020

Yingying Sang

3

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2 February 2020

Catherine A Foss

4

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2 February 2020

Kathrine Cornet

5

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2 February 2020

Sameena Muzamil

6

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2 February 2020

Jin Kim

8

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2 February 2020

John Laterra

9

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2 February 2020

publication date

7 July 2009

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Molecular Cancer Therapeutics

2 February 2020

published in

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2 February 2020

volume

8

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2 February 2020

issue

7

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2 February 2020

page(s)

1751-1760

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describes a project that uses

2 February 2020

ImageJ

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11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC2846399/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Transcription-dependent epidermal growth factor receptor activation by hepatocyte growth factor

21 June 2018

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Signaling networks assembled by oncogenic EGFR and c-Met

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MET amplification occurs with or without T790M mutations in EGFR mutant lung tumors with acquired resistance to gefitinib or erlotinib

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Coactivation of receptor tyrosine kinases affects the response of tumor cells to targeted therapies

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Quantitative analysis of EGFRvIII cellular signaling networks reveals a combinatorial therapeutic strategy for glioblastoma

21 June 2018

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Epidermal growth factor receptor plays a significant role in hepatocyte growth factor mediated biological responses in mammary epithelial cells

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MET amplification leads to gefitinib resistance in lung cancer by activating ERBB3 signaling

21 June 2018

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A novel one-armed anti-c-Met antibody inhibits glioblastoma growth in vivo

21 June 2018

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Systemic anti-hepatocyte growth factor monoclonal antibody therapy induces the regression of intracranial glioma xenografts

21 June 2018

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Fully human monoclonal antibodies to hepatocyte growth factor with therapeutic potential against hepatocyte growth factor/c-Met-dependent human tumors

21 June 2018

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Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors.

21 June 2018

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Targeting the c-Met pathway potentiates glioblastoma responses to gamma-radiation

21 June 2018

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Resistance to tyrosine kinase inhibition by mutant epidermal growth factor receptor variant III contributes to the neoplastic phenotype of glioblastoma multiforme

21 June 2018

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The Met kinase inhibitor SU11274 exhibits a selective inhibition pattern toward different receptor mutated variants

21 June 2018

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Met, metastasis, motility and more

21 June 2018

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A selective small molecule inhibitor of c-Met kinase inhibits c-Met-dependent phenotypes in vitro and exhibits cytoreductive antitumor activity in vivo

21 June 2018

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Mechanism of biological synergy between cellular Src and epidermal growth factor receptor

21 June 2018

1 reference

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Scatter factor promotes motility of human glioma and neuromicrovascular endothelial cells

21 June 2018

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Scatter factor/hepatocyte growth factor gene transfer enhances glioma growth and angiogenesis in vivo

21 June 2018

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HGF receptor associates with the anti-apoptotic protein BAG-1 and prevents cell death

21 June 2018

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A mutant epidermal growth factor receptor common in human glioma confers enhanced tumorigenicity

21 June 2018

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Determination of subcutaneous tumor size in athymic (nude) mice

21 June 2018

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Characterization of monoclonal antibodies to two Treponema denticola serotypes by the indirect fluorescent-antibody assay

21 June 2018

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Cortical region of interest definition on SPECT brain images using X-ray CT registration

21 June 2018

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21 June 2018

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Use of an orthotopic xenograft model for assessing the effect of epidermal growth factor receptor amplification on glioblastoma radiation response.

21 June 2018

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30 October 2018

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A selective small molecule c-MET Inhibitor, PHA665752, cooperates with rapamycin

30 October 2018

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Mutant epidermal growth factor receptor up-regulates molecular effectors of tumor invasion

30 October 2018

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In vivo targeting of SF/HGF and c-met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis

30 October 2018

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Specific Growth Rate versus Doubling Time for Quantitative Characterization of Tumor Growth Rate

30 October 2018

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10.1158/1535-7163.MCT-09-0188

30 October 2018

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19584231%20AND%20SRC:MED&resulttype=core&format=json

2 February 2020

1 reference

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2 February 2020

PubMed publication ID

19584231

1 reference