Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers. (Q34043681)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849900%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

title

Epigenome editing by a CRISPR-Cas9-based acetyltransferase activates genes from promoters and enhancers (English)

1 reference

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4 March 2020

0 references

0 references

1 reference

1

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4 March 2020

Timothy E. Reddy

6

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4 March 2020

author name string

Anthony M D'Ippolito

2

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4 March 2020

Christopher M Vockley

3

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4 March 2020

Pratiksha I Thakore

4

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4 March 2020

Charles A Gersbach

7

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4 March 2020

Gregory E Crawford

5

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4 March 2020

language of work or name

English

0 references

publication date

6 April 2015

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4 March 2020

1 reference

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4 March 2020

volume

33

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4 March 2020

issue

5

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4 March 2020

page(s)

510-517

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Highly efficient Cas9-mediated transcriptional programming

4 March 2020

cites work

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28 July 2018

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A split-Cas9 architecture for inducible genome editing and transcription modulation

28 July 2018

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Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex

28 July 2018

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28 July 2018

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28 July 2018

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Comparison of TALE designer transcription factors and the CRISPR/dCas9 in regulation of gene expression by targeting enhancers

28 July 2018

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28 July 2018

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28 July 2018

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28 July 2018

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Genome-wide analysis reveals characteristics of off-target sites bound by the Cas9 endonuclease.

28 July 2018

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Engineered zinc-finger transcription factors activate OCT4 (POU5F1), SOX2, KLF4, c-MYC (MYC) and miR302/367.

28 July 2018

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Direct activation of human and mouse Oct4 genes using engineered TALE and Cas9 transcription factors.

28 July 2018

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Targeted DNA demethylation and activation of endogenous genes using programmable TALE-TET1 fusion proteins

28 July 2018

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Orthogonal Cas9 proteins for RNA-guided gene regulation and editing

28 July 2018

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Locus-specific editing of histone modifications at endogenous enhancers

28 July 2018

1 reference

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Multiplexed activation of endogenous genes by CRISPR-on, an RNA-guided transcriptional activator system

28 July 2018

1 reference

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Structure of the p300 catalytic core and implications for chromatin targeting and HAT regulation

28 July 2018

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CAS9 transcriptional activators for target specificity screening and paired nickases for cooperative genome engineering

28 July 2018

1 reference

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CRISPR RNA-guided activation of endogenous human genes

28 July 2018

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RNA-guided gene activation by CRISPR-Cas9-based transcription factors

28 July 2018

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CRISPR-mediated modular RNA-guided regulation of transcription in eukaryotes

28 July 2018

1 reference

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Histone acetylation contributes to chromatin looping between the locus control region and globin gene by influencing hypersensitive site formation

28 July 2018

1 reference

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Repurposing CRISPR as an RNA-guided platform for sequence-specific control of gene expression

28 July 2018

1 reference

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Robust, synergistic regulation of human gene expression using TALE activators

28 July 2018

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Identification of biologically relevant enhancers in human erythroid cells

28 July 2018

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RNA-guided human genome engineering via Cas9

28 July 2018

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Multiplex genome engineering using CRISPR/Cas systems

28 July 2018

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28 July 2018

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A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity

28 July 2018

1 reference

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Epigenetic reprogramming of cancer cells via targeted DNA methylation.

28 July 2018

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28 July 2018

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Life and death of transcriptional co-activator p300.

28 July 2018

1 reference

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A unique chromatin signature uncovers early developmental enhancers in humans

28 July 2018

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The NIH Roadmap Epigenomics Mapping Consortium

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

The Sequence Alignment/Map format and SAMtools

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

Isolation of human iPS cells using EOS lentiviral vectors to select for pluripotency

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

Enzymatic assembly of DNA molecules up to several hundred kilobases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

ChIP-seq accurately predicts tissue-specific activity of enhancers

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

Analyzing real-time PCR data by the comparative C(T) method

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

In vivo selection of combinatorial libraries and designed affinity maturation of polydactyl zinc finger transcription factors for ICAM-1 provides new insights into gene regulation

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

Acetylation of RelA at discrete sites regulates distinct nuclear functions of NF-kappaB.

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

Long-range chromatin regulatory interactions in vivo

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

Positive and negative regulation of endogenous genes by designed transcription factors

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

The transcriptional coactivators p300 and CBP are histone acetyltransferases

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

Genome editing. The new frontier of genome engineering with CRISPR-Cas9

28 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

Genome-wide binding of the CRISPR endonuclease Cas9 in mammalian cells

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

Reprogramming to pluripotency using designer TALE transcription factors targeting enhancers

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

Tunable and multifunctional eukaryotic transcription factors based on CRISPR/Cas

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

Optical control of mammalian endogenous transcription and epigenetic states

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

Synergistic and tunable human gene activation by combinations of synthetic transcription factors

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

Sequential recruitment of HAT and SWI/SNF components to condensed chromatin by VP16.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

Gene-specific targeting of H3K9 methylation is sufficient for initiating repression in vivo.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

Two upstream enhancers collaborate to regulate the spatial patterning and timing of MyoD transcription during mouse development.

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

Comparative analysis of human, bovine, and murine Oct-4 upstream promoter sequences

28 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4430400

Eukaryotic activators function during multiple steps of preinitiation complex assembly

28 October 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/25849900

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NBT.3199

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849900%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849900%20AND%20SRC:MED&resulttype=core&format=json

4 March 2020

PubMed publication ID

25849900

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25849900%20AND%20SRC:MED&resulttype=core&format=json