HLA-E-restricted regulatory CD8(+) T cells are involved in development and control of human autoimmune type 1 diabetes (Q34162213)

31 July 2017

title

HLA-E-restricted regulatory CD8(+) T cells are involved in development and control of human autoimmune type 1 diabetes (English)

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31 July 2017

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Hong Jiang

1

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31 July 2017

Steve M Canfield

2

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31 July 2017

Mary P Gallagher

3

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31 July 2017

Hong H Jiang

4

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31 July 2017

Yihua Jiang

5

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31 July 2017

Zongyu Zheng

6

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31 July 2017

Leonard Chess

7

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31 July 2017

language of work or name

English

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publication date

27 September 2010

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Journal of Clinical Investigation

31 July 2017

published in

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31 July 2017

volume

120

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31 July 2017

issue

10

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31 July 2017

page(s)

3641-3650

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How the immune system achieves self-nonself discrimination during adaptive immunity

31 July 2017

cites work

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The specificity of T cell regulation that enables self-nonself discrimination in the periphery

5 July 2018

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Regulation of CD8+ regulatory T cells: Interruption of the NKG2A-Qa-1 interaction allows robust suppressive activity and resolution of autoimmune disease

5 July 2018

1 reference

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Qa-1/HLA-E-restricted regulatory CD8+ T cells and self-nonself discrimination: an essay on peripheral T-cell regulation

5 July 2018

1 reference

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Perceiving the avidity of T cell activation can be translated into peripheral T cell regulation

5 July 2018

1 reference

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Regulation of activated CD4+ T cells by NK cells via the Qa-1-NKG2A inhibitory pathway.

5 July 2018

1 reference

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T cells with low avidity for a tissue-restricted antigen routinely evade central and peripheral tolerance and cause autoimmunity

5 July 2018

1 reference

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Developmental control of CD8 T cell-avidity maturation in autoimmune diabetes

5 July 2018

1 reference

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An affinity/avidity model of peripheral T cell regulation

5 July 2018

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Whither T-suppressors: if they didn't exist would we have to invent them?

5 July 2018

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Actively acquired tolerance of foreign cells

5 July 2018

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Protein expression and peptide binding suggest unique and interacting functional roles for HLA-E, F, and G in maternal-placental immune recognition

5 July 2018

1 reference

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Regulatory CD8+ T cells fine-tune the myelin basic protein-reactive T cell receptor V beta repertoire during experimental autoimmune encephalomyelitis

5 July 2018

1 reference

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A signal peptide derived from hsp60 binds HLA-E and interferes with CD94/NKG2A recognition

5 July 2018

1 reference

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Negative selection during the peripheral immune response to antigen

5 July 2018

1 reference

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The specific regulation of immune responses by CD8+ T cells restricted by the MHC class Ib molecule, Qa-1.

5 July 2018

1 reference

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Qa-1b binds conserved class I leader peptides derived from several mammalian species

5 July 2018

1 reference

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HLA-E surface expression depends on binding of TAP-dependent peptides derived from certain HLA class I signal sequences

5 July 2018

1 reference

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The cognitive paradigm and the immunological homunculus

5 July 2018

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Thymus and Lymphohemopoietic Cells: Their Role in T Cell Maturation in Selection of T Cells' H-2-Restriction-Specificity and in H-2 Linked Ir Gene Control

5 July 2018

1 reference

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An immunologic homunculus for type 1 diabetes.

5 July 2018

1 reference

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Analysis of regulatory CD8 T cells in Qa-1-deficient mice

28 October 2018

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T Cell Tolerance Based on Avidity Thresholds Rather Than Complete Deletion Allows Maintenance of Maximal Repertoire Diversity

28 October 2018

1 reference

12 December 2020

Impact of negative selection on the T cell repertoire reactive to a self-peptide: a large fraction of T cell clones escapes clonal deletion

1 reference

12 December 2020

T cell tolerance by clonal elimination in the thymus

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12 December 2020

Deletion of self-reactive T cells before entry into the thymus medulla

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12 December 2020

Recognizing self from nonself

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12 December 2020

Lower receptor avidity required for thymic clonal deletion than for effector T-cell function

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12 December 2020

Combined analysis of autoantibodies improves prediction of IDDM in islet cell antibody-positive relatives

1 reference

12 December 2020

Identification of a tap-dependent leader peptide recognized by alloreactive T cells specific for a class Ib antigen

1 reference

12 December 2020

Prediction of type I diabetes in first-degree relatives using a combination of insulin, GAD, and ICA512bdc/IA-2 autoantibodies

1 reference

12 December 2020

Qa-1 interaction and T cell recognition of the Qa-1 determinant modifier peptide

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12 December 2020

Regulation of immune responses by T cells

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12 December 2020

Identifiers

DOI

10.1172/JCI43522

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31 July 2017

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31 July 2017

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