The differential effect of NAT2 variant alleles permits refinement in phenotype inference and identifies a very slow acetylation genotype (Q34412637)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22970273%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

title

The differential effect of NAT2 variant alleles permits refinement in phenotype inference and identifies a very slow acetylation genotype (English)

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13 February 2020

6

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13 February 2020

José Agundez

7

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13 February 2020

1

Jhon D Ruiz

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13 February 2020

author name string

Carmen Martínez

2

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13 February 2020

Kristin Anderson

3

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13 February 2020

Myron Gross

4

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13 February 2020

Nicholas P Lang

5

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13 February 2020

language of work or name

English

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publication date

6 September 2012

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13 February 2020

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13 February 2020

volume

7

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13 February 2020

issue

9

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13 February 2020

page(s)

e44629

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Creative Commons Attribution 4.0 International

13 February 2020

copyright license

start time

6 September 2012

1 reference

April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

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6 July 2018

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Polymorphisms of human N-acetyltransferases and cancer risk

6 July 2018

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Interethnic and intraethnic variability of NAT2 single nucleotide polymorphisms

6 July 2018

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Structure/function evaluations of single nucleotide polymorphisms in human N-acetyltransferase 2

6 July 2018

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N-acetyltransferases: lessons learned from eighty years of research

6 July 2018

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Unraveling ambiguous NAT2 genotyping data

6 July 2018

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Cigarette smoking, N-acetyltransferase genes and the risk of advanced colorectal adenoma

6 July 2018

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Arylamine N-acetyltransferase activity in man.

6 July 2018

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The use of caffeine as a metabolic probe for human drug metabolizing enzymes

6 July 2018

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An alternative test for acetylator phenotyping with caffeine.

6 July 2018

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Determination of CYP1A2 and NAT2 phenotypes in human populations by analysis of caffeine urinary metabolites.

6 July 2018

1 reference

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N-acetyltransferase 2 polymorphisms and risk of anti-tuberculosis drug-induced hepatotoxicity in Caucasians

6 July 2018

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Dietary intake of heterocyclic amines and benzo(a)pyrene: associations with pancreatic cancer

27 October 2018

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Re-investigation of the concordance of human NAT2 phenotypes and genotypes

27 October 2018

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Meat intake and cooking techniques: associations with pancreatic cancer

27 October 2018

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Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis

27 October 2018

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Genetic polymorphism of N-acetyltransferases, glutathione S-transferase M1 and NAD(P)H:quinone oxidoreductase in relation to malignant and benign pancreatic disease risk. The International Pancreatic Disease Study Group

27 October 2018

1 reference

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Analysis of within-subject variation of caffeine metabolism when used to determine cytochrome P4501A2 and N-acetyltransferase-2 activities.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435299

Genotyping NAT2 with only two SNPs (rs1041983 and rs1801280) outperforms the tagging SNP rs1495741 and is equivalent to the conventional 7-SNP NAT2 genotype

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3435299

Genetic control of isoniazid metabolism in man

9 December 2018

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12 December 2020

The determination of the isoniazid inactivator phenotype

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12 December 2020

N-acetyltransferase SNPs: emerging concepts serve as a paradigm for understanding complexities of personalized medicine

1 reference

12 December 2020

Distribution and concordance of N-acetyltransferase genotype and phenotype in an American population

1 reference

12 December 2020

10.1371/JOURNAL.PONE.0044629

Identifiers

DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22970273%20AND%20SRC:MED&resulttype=core&format=json

13 February 2020

0 references

1 reference

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13 February 2020

PubMed publication ID

22970273

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22970273%20AND%20SRC:MED&resulttype=core&format=json