Hyperglucagonemia and insulin-mediated glucose metabolism (Q34560371)

3 August 2017

title

Hyperglucagonemia and insulin-mediated glucose metabolism (English)

1 reference

3 August 2017

1 reference

4

R A DeFronzo

1 reference

3 August 2017

S Del Prato

1

1 reference

3 August 2017

P Castellino

series ordinal

2

1 reference

3 August 2017

D C Simonson

series ordinal

3

1 reference

3 August 2017

language of work or name

English

0 references

publication date

1 February 1987

1 reference

Journal of Clinical Investigation

3 August 2017

published in

1 reference

3 August 2017

volume

79

1 reference

3 August 2017

issue

2

1 reference

3 August 2017

page(s)

547-556

1 reference

The glucose fatty-acid cycle. Its role in insulin sensitivity and the metabolic disturbances of diabetes mellitus

3 August 2017

cites work

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

7 July 2018

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

In vitro reversal of the fasting state of liver metabolism in the rat. Reevaluation of the roles of insulin and glucose

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Mechanisms of insulin resistance in obesity and noninsulin-dependent (type II) diabetes.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Insulin sensitivity, binding, and kinetics in pancreatogenic and type I diabetes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Site of insulin resistance in type 1 diabetes: insulin-mediated glucose disposal in vivo in relation to insulin binding and action in adipocytes in vitro

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Insulin sensitivity in newly diagnosed type 1 diabetics after ketoacidosis and after three months of insulin therapy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Insulin-Mediated Glucose Disposal in Type I Diabetes: Evidence for Insulin Resistance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

New concepts in the pathogenesis and treatment of noninsulin-dependent diabetes mellitus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Epinephrine-induced insulin resistance in man.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Prolonged infusion of somatostatin with glucagon replacement increases plasma glucose and glucose turnover in man.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Effect of fatty acids on glucose production and utilization in man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Liver diseases and diabetes mellitus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Measurement and validation of nonsteady turnover rates with applications to the inulin and glucose systems.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Effects of somatostatin on plasma glucose and glucagon levels in human diabetes mellitus. Pathophysiologic and therapeutic implications.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Regulation of glucose utilization in adipose cells and muscle after long-term experimental hyperinsulinemia in rats

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Production of insulin resistance by hyperinsulinaemia in man.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Metabolism of Forearm Tissues in Man: Studies with Glucagon

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Hormonal control of ketogenesis. Rapid activation of hepatic ketogenic capacity in fed rats by anti-insulin serum and glucagon

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Demonstration of insulin resistance in untreated adult onset diabetic subjects with fasting hyperglycemia

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Influence of physiologic hyperglucagonemia on basal and insulin-inhibited splanchnic glucose output in normal man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Nonketotic diabetes mellitus: insulin deficiency or insulin resistance?

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Insulin resistance, insulin insensitivity, and insulin unresponsiveness: a necessary distinction

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Effect of Intermittent Endogenous Hyperglucagonemia on Glucose Homeostasis in Normal and Diabetic Man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Persistent effect of sustained hyperglucagonemia on glucose production in man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Investigation of Insulin Sensitivity in Treated Subjects with Ketosis-prone Diabetes Mellitus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Hyperglycemia inhibits glucose production in man independent of changes in glucoregulatory hormones

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Glucose clamp technique: a method for quantifying insulin secretion and resistance

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Insulin Sensitivity and Insulin Binding to Monocytes in Maturity-Onset Diabetes

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Role of glucagon in the pathogenesis of diabetes: The status of the controversy

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Insulin Binding to Monocytes and Insulin Action in Human Obesity, Starvation, and Refeeding

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Influence of hyperinsulinemia, hyperglycemia, and the route of glucose administration on splanchnic glucose exchange

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Effects of Chronic Glucagon Excess on Hepatic Metabolism

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Transient Stimulatory Effect of Sustained Hyperglucagonemia on Splanchnic Glucose Production in Normal and Diabetic Man

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

The essential role of glucagon in the pathogenesis of diabetes mellitus

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Mechanism and significance of insulin resistance in non-insulin-dependent diabetes mellitus.

7 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Hepatic and peripheral insulin resistance: a common feature of type 2 (non-insulin-dependent) and type 1 (insulin-dependent) diabetes mellitus.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Nutritional influences on lipogenesis and thermogenesis after a carbohydrate meal.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Calculation of substrate oxidation rates in vivo from gaseous exchange.

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Glucoregulatory responses in normal and diabetic dogs recorded by a new tracer method

27 October 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=424124

Differential Sensitivity of Glycogenolysis and Gluconeogenesis to Insulin Infusions in Dogs

27 October 2018

1 reference

12 December 2020

Carbohydrate storage in man: speculations and some quantitative considerations

1 reference

12 December 2020

Effect of hyperglycemia independent of changes in insulin or glucagon on lipolysis in the conscious dog

1 reference

12 December 2020

Differential time course of glucagon's effect on glycogenolysis and gluconeogenesis in the conscious dog

1 reference

12 December 2020

The acute metabolic effects of glucagon and its interactions with insulin in forearm tissue

1 reference

12 December 2020

The effect of insulin on the disposal of intravenous glucose. Results from indirect calorimetry and hepatic and femoral venous catheterization

1 reference

12 December 2020

Absence of islet alpha cell function in pancreatectomized patients

1 reference

12 December 2020

Transient hepatic response to glucagon in man: role of insulin and hyperglycemia

1 reference

12 December 2020

The effect of growth hormone on glucose metabolism and insulin secretion in man

1 reference

12 December 2020

Effect of long chain triglyceride infusion on glucose metabolism in man

1 reference

12 December 2020

The relative importance of first- and second-phase insulin secretion in countering the action of glucagon on glucose turnover in the conscious dog

1 reference

12 December 2020

Regulation of Splanchnic and Peripheral Glucose Uptake by Insulin and Hyperglycemia in Man

1 reference

12 December 2020

Insulin resistance is a prominent feature of insulin-dependent diabetes

1 reference

12 December 2020

Effects of Chronic Glucocorticoid Excess in Man on Insulin Binding to Circulating Cells: Differences between Endogenous and Exogenous Hypercorticism

1 reference

12 December 2020

Minimal increases in glucagon levels enhance glucose production in man with partial hypoinsulinemia

1 reference

12 December 2020

Studies on the mechanism by which exogenous glucose is converted into liver glycogen in the rat. A direct or an indirect pathway?

1 reference

12 December 2020

Insulin resistance in Cushing's syndrome

1 reference

12 December 2020

Chronic hyperglucagonemia in rats: Effects on insulin, substrates, and hepatic enzymes of intermediary metabolism

1 reference

12 December 2020

Effect of insulin replacement on intermediary metabolism in diabetes secondary to pancreatectomy

1 reference

12 December 2020

Insulin Sensitivity in Pancreatitis, Liver Diseases, Steroid Treatment and Hyperthyroidism Assessed by Glucose, Insulin and Somatostatin Infusion

1 reference

12 December 2020

Increased Insulin Responsiveness In Vivo and In Vitro Consequent to Induced Hyperinsulinemia in the Rat

1 reference

12 December 2020

Insulin resistance in Type 1 (insulin-dependent) diabetes: dependence on plasma insulin concentration

1 reference

12 December 2020

Impaired insulin action in newly diagnosed type 1 (insulin-dependent) diabetes mellitus

1 reference

12 December 2020

Hepatomegaly and diabetes mellitus

1 reference

12 December 2020

Influences of glucose loading and of injected insulin on hepatic glucose output

1 reference

12 December 2020

COLORIMETRIC ULTRAMICRO METHOD FOR THE DETERMINATION OF FREE FATTY ACIDS

1 reference

12 December 2020

Coated Charcoal Immunoassay of Insulin

1 reference

12 December 2020

Effect of Glucagon and of Insulin on Serum Free Fatty Acids in Normal and Depancreatized Dogs

1 reference

12 December 2020

Carbohydrate and lipid oxidation in normal human subjects: Its influence on glucose tolerance and insulin response to glucose

1 reference

12 December 2020

Effect of interaction between insulin and glucagon on glucose turnover and FFA concentration in normal and depancreatized dogs

1 reference

12 December 2020

Prevention of human diabetic ketoacidosis by somatostatin. Evidence for an essential role of glucagon

1 reference

12 December 2020

Identifiers

DOI

10.1172/JCI112846

1 reference

3 August 2017

1 reference

3 August 2017

1 reference