Sirtuins in aging and disease (Q34770789)

4 August 2017

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title

Sirtuins in aging and disease (English)

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4 August 2017

1

L Guarente

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4 August 2017

publication date

1 January 2007

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Cold Spring Harbor Symposia on Quantitative Biology

4 August 2017

published in

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4 August 2017

volume

72

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4 August 2017

page(s)

483-488

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Asymmetric inheritance of oxidatively damaged proteins during cytokinesis

4 August 2017

cites work

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https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Sirt1 regulates aging and resistance to oxidative stress in the heart

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Mitochondrial oxygen consumption and reactive oxygen species production are independently modulated: implications for aging studies.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Higher respiratory activity decreases mitochondrial reactive oxygen release and increases life span in Saccharomyces cerevisiae.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Resveratrol improves health and survival of mice on a high-calorie diet

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Two neurons mediate diet-restriction-induced longevity in C. elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

The Sir2 family of protein deacetylases

21 January 2018

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https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Sirt1 regulates insulin secretion by repressing UCP2 in pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Stress-dependent regulation of FOXO transcription factors by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

SIRT1 protects against microglia-dependent amyloid-beta toxicity through inhibiting NF-kappaB signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Calorie restriction increases muscle mitochondrial biogenesis in healthy humans

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis

21 January 2018

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https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Calorie restriction promotes mammalian cell survival by inducing the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

The dihydrolipoamide acetyltransferase is a novel metabolic longevity factor and is required for calorie restriction-mediated life span extension

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Metabolic control of muscle mitochondrial function and fatty acid oxidation through SIRT1/PGC-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Sirtuins as potential targets for metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Aging: a theory based on free radical and radiation chemistry

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Sir2-independent life span extension by calorie restriction in yeast

21 January 2018

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https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Increased life span due to calorie restriction in respiratory-deficient yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Regulation of yeast replicative life span by TOR and Sch9 in response to nutrients

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

SIRT1 deacetylase protects against neurodegeneration in models for Alzheimer's disease and amyotrophic lateral sclerosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

FoxO1 protects against pancreatic beta cell failure through NeuroD and MafA induction

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1alpha

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

HST2 mediates SIR2-independent life-span extension by calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Calorie restriction extends yeast life span by lowering the level of NADH.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Metabolic control through the PGC-1 family of transcription coactivators

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Negative control of p53 by Sir2alpha promotes cell survival under stress

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Mammalian SIRT1 represses forkhead transcription factors

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Increased dosage of mammalian Sir2 in pancreatic beta cells enhances glucose-stimulated insulin secretion in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS.

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Sirt1 promotes fat mobilization in white adipocytes by repressing PPAR-gamma

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Neuronal SIRT1 activation as a novel mechanism underlying the prevention of Alzheimer disease amyloid neuropathology by calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Sir2 mediates longevity in the fly through a pathway related to calorie restriction

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Nutrient control of glucose homeostasis through a complex of PGC-1alpha and SIRT1

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Extrachromosomal rDNA circles--a cause of aging in yeast

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

A mitochondrial paradigm of metabolic and degenerative diseases, aging, and cancer: a dawn for evolutionary medicine

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Imatinib mesylate blocks a non-Smad TGF-beta pathway and reduces renal fibrogenesis in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Sirtuin activators mimic caloric restriction and delay ageing in metazoans

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Modulation of NF-kappaB-dependent transcription and cell survival by the SIRT1 deacetylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

Dietary restriction protects hippocampal neurons against the death-promoting action of a presenilin-1 mutation

21 January 2018

1 reference

https://api.crossref.org/works/10.1101%2FSQB.2007.72.024

21 January 2018

Identifiers

DOI

10.1101/SQB.2007.72.024

1 reference

4 August 2017

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