Stromal cells in tumor microenvironment and breast cancer (Q35609967)

9 August 2017

title

Stromal cells in tumor microenvironment and breast cancer (English)

1 reference

9 August 2017

1 reference

Yan Mao

1

1 reference

9 August 2017

Evan T Keller

2

1 reference

9 August 2017

David H Garfield

3

1 reference

9 August 2017

Kunwei Shen

4

1 reference

9 August 2017

Jianhua Wang

5

1 reference

9 August 2017

publication date

1 June 2013

1 reference

Cancer and Metastasis Reviews

9 August 2017

published in

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9 August 2017

volume

32

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9 August 2017

issue

1-2

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9 August 2017

page(s)

303-315

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Unlike pancreatic cancer cells pancreatic cancer associated fibroblasts display minimal gene induction after 5-aza-2'-deoxycytidine

9 August 2017

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Silencing of miR-148a in cancer-associated fibroblasts results in WNT10B-mediated stimulation of tumor cell motility

12 July 2018

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12 July 2018

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Cancer-associated fibroblasts induce matrix metalloproteinase-mediated cetuximab resistance in head and neck squamous cell carcinoma cells

12 July 2018

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Fibroblast-secreted hepatocyte growth factor mediates epidermal growth factor receptor tyrosine kinase inhibitor resistance in triple-negative breast cancers through paracrine activation of Met

12 July 2018

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A CXCL1 paracrine network links cancer chemoresistance and metastasis

12 July 2018

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p16(INK4A) represses the paracrine tumor-promoting effects of breast stromal fibroblasts.

12 July 2018

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Downregulation of miR-92a is associated with aggressive breast cancer features and increased tumour macrophage infiltration

12 July 2018

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Breast cancer cells induce stromal fibroblasts to secrete ADAMTS1 for cancer invasion through an epigenetic change

12 July 2018

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CCL2 mediates cross-talk between cancer cells and stromal fibroblasts that regulates breast cancer stem cells

12 July 2018

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Contribution of Fibroblast and Mast Cell (Afferent) and Tumor (Efferent) IL-6 Effects within the Tumor Microenvironment

12 July 2018

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12 July 2018

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Tumor-associated macrophages in breast cancer: distinct subsets, distinct functions

12 July 2018

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Role of cancer-associated fibroblasts in breast cancer development and prognosis

12 July 2018

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12 July 2018

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Anti-estrogen resistance in breast cancer is induced by the tumor microenvironment and can be overcome by inhibiting mitochondrial function in epithelial cancer cells

12 July 2018

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Leukocyte complexity predicts breast cancer survival and functionally regulates response to chemotherapy

12 July 2018

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Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells

12 July 2018

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The tumor microenvironment modulates tamoxifen resistance in breast cancer: a role for soluble stromal factors and fibronectin through β1 integrin

12 July 2018

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Interleukin-8 derived from local tissue-resident stromal cells promotes tumor cell invasion

12 July 2018

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Leukocyte composition of human breast cancer

12 July 2018

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Relevance of breast cancer hormone receptors and other factors to the efficacy of adjuvant tamoxifen: patient-level meta-analysis of randomised trials

12 July 2018

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Mesenchymal stem cells and carcinoma-associated fibroblasts sensitize breast cancer cells in 3D cultures to kinase inhibitors.

12 July 2018

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CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis

12 July 2018

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12 July 2018

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12 July 2018

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Control of tumor and microenvironment cross-talk by miR-15a and miR-16 in prostate cancer

12 July 2018

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CCL18 from tumor-associated macrophages promotes breast cancer metastasis via PITPNM3

12 July 2018

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Tumour-infiltrating regulatory T cells stimulate mammary cancer metastasis through RANKL-RANK signalling

12 July 2018

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Tumor-associated macrophages in breast cancer as potential biomarkers for new treatments and diagnostics

12 July 2018

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MicroRNAs in embryonic stem cell function and fate

12 July 2018

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Caveolin-1 and mitochondrial SOD2 (MnSOD) function as tumor suppressors in the stromal microenvironment: a new genetically tractable model for human cancer associated fibroblasts

12 July 2018

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Autocrine TGF-beta and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts

12 July 2018

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The role of miR-31 and its target gene SATB2 in cancer-associated fibroblasts.

12 July 2018

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Proliferating macrophages associated with high grade, hormone receptor negative breast cancer and poor clinical outcome

12 July 2018

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Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: A new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells

12 July 2018

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STAT3 Activation of miR-21 and miR-181b-1 via PTEN and CYLD Are Part of the Epigenetic Switch Linking Inflammation to Cancer

12 July 2018

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Reciprocal activation of prostate cancer cells and cancer-associated fibroblasts stimulates epithelial-mesenchymal transition and cancer stemness

12 July 2018

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Zoledronic acid impairs myeloid differentiation to tumour-associated macrophages in mesothelioma

12 July 2018

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Specific protein and miRNA patterns characterise tumour-associated fibroblasts in bladder cancer

12 July 2018

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Depletion of tumor-associated macrophages enhances the effect of sorafenib in metastatic liver cancer models by antimetastatic and antiangiogenic effects.

12 July 2018

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Tumor cells induce the cancer associated fibroblast phenotype via caveolin-1 degradation: implications for breast cancer and DCIS therapy with autophagy inhibitors

12 July 2018

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Unraveling the obesity and breast cancer links: a role for cancer-associated adipocytes?

12 July 2018

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12 July 2018

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Transient tumor-fibroblast interactions increase tumor cell malignancy by a TGF-Beta mediated mechanism in a mouse xenograft model of breast cancer

12 July 2018

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Forkhead box F1 regulates tumor-promoting properties of cancer-associated fibroblasts in lung cancer

12 July 2018

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12 July 2018

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Up-regulation of pro-inflammatory genes as adaptation to hypoxia in MCF-7 cells and in human mammary invasive carcinoma microenvironment

12 July 2018

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The reverse Warburg effect: aerobic glycolysis in cancer associated fibroblasts and the tumor stroma

12 July 2018

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An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation

12 July 2018

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Pten in stromal fibroblasts suppresses mammary epithelial tumours

12 July 2018

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Zoledronic acid repolarizes tumour-associated macrophages and inhibits mammary carcinogenesis by targeting the mevalonate pathway.

12 July 2018

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Breast cancer subtypes based on ER/PR and Her2 expression: comparison of clinicopathologic features and survival

12 July 2018

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Inhibition of vascular endothelial growth factor reduces angiogenesis and modulates immune cell infiltration of orthotopic breast cancer xenografts.

12 July 2018

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Fibroblast growth factor receptor 2-positive fibroblasts provide a suitable microenvironment for tumor development and progression in esophageal carcinoma.

12 July 2018

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Interleukin 6 secreted from adipose stromal cells promotes migration and invasion of breast cancer cells

12 July 2018

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Tissue resident stem cells produce CCL5 under the influence of cancer cells and thereby promote breast cancer cell invasion

12 July 2018

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Stromal cell expression of caveolin-1 predicts outcome in breast cancer

12 July 2018

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Mesenchymal stem cell transition to tumor-associated fibroblasts contributes to fibrovascular network expansion and tumor progression

12 July 2018

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Cyclooxygenase-2 (cox-2) blockade in the chemoprevention of cancers of the colon, breast, prostate, and lung

12 July 2018

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Role of COX-2 in epithelial-stromal cell interactions and progression of ductal carcinoma in situ of the breast

12 July 2018

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Cancer-associated fibroblasts and tumor growth--bystanders turning into key players

12 July 2018

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Tissue-resident stem cells promote breast cancer growth and metastasis

12 July 2018

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MicroRNAs: key regulators of stem cells

12 July 2018

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Global hypomethylation of genomic DNA in cancer-associated myofibroblasts.

12 July 2018

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MicroRNA: basic mechanisms and transcriptional regulatory networks for cell fate determination

12 July 2018

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Mesenchymal stem cells derived from human adipose tissues favor tumor cell growth in vivo

12 July 2018

1 reference

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Regulation of in situ to invasive breast carcinoma transition

12 July 2018

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Stromal gene expression predicts clinical outcome in breast cancer

12 July 2018

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Amino-biphosphonate-mediated MMP-9 inhibition breaks the tumor-bone marrow axis responsible for myeloid-derived suppressor cell expansion and macrophage infiltration in tumor stroma

12 July 2018

1 reference

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Targeting tumor-associated macrophages and inhibition of MCP-1 reduce angiogenesis and tumor growth in a human melanoma xenograft

12 July 2018

1 reference

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Function and localization of microRNAs in mammalian cells

12 July 2018

1 reference

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p53 Attenuates cancer cell migration and invasion through repression of SDF-1/CXCL12 expression in stromal fibroblasts

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Monocyte/macrophage infiltration in tumors: modulators of angiogenesis

12 July 2018

1 reference

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Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach

12 July 2018

1 reference

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Targeting tumor-associated fibroblasts improves cancer chemotherapy by increasing intratumoral drug uptake

12 July 2018

1 reference

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IL-2 immunotoxin therapy modulates tumor-associated regulatory T cells and leads to lasting immune-mediated rejection of breast cancers in neu-transgenic mice

12 July 2018

1 reference

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12 July 2018

Fibroblasts in cancer

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Distinct role of macrophages in different tumor microenvironments

12 July 2018

1 reference

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Macrophages direct tumour histology and clinical outcome in a colon cancer model

12 July 2018

1 reference

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MicroRNA gene expression deregulation in human breast cancer

12 July 2018

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Distinct epigenetic changes in the stromal cells of breast cancers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Stromal fibroblasts present in invasive human breast carcinomas promote tumor growth and angiogenesis through elevated SDF-1/CXCL12 secretion

12 July 2018

1 reference

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BRCA1 promoter methylation in sporadic breast tumors: relationship to gene expression profiles

12 July 2018

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Adipocyte-derived collagen VI affects early mammary tumor progression in vivo, demonstrating a critical interaction in the tumor/stroma microenvironment

12 July 2018

1 reference

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Breast fibroblasts modulate epithelial cell proliferation in three-dimensional in vitro co-culture

12 July 2018

1 reference

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The significance of focal myoepithelial cell layer disruptions in human breast tumor invasion: a paradigm shift from the "protease-centered" hypothesis

12 July 2018

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The p16INK4a-RB pathway: molecular link between cellular senescence and tumor suppression

12 July 2018

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Molecular characterization of the tumor microenvironment in breast cancer

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Mechanisms of bone metastasis

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Colony-stimulating factor 1 promotes progression of mammary tumors to malignancy

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

The biology of chemokines and their receptors

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Basic fibroblast growth factor expression is increased in human renal fibrogenesis and may mediate autocrine fibroblast proliferation

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Heterocycle-containing bisphosphonates cause apoptosis and inhibit bone resorption by preventing protein prenylation: evidence from structure-activity relationships in J774 macrophages.

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Angiogenesis and inflammation in invasive carcinoma of the breast

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Reduction of caveolin and caveolae in oncogenically transformed cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Tumors: wounds that do not heal. Similarities between tumor stroma generation and wound healing

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Effect of bisphosphonates on proliferation and viability of mouse bone marrow-derived macrophages

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Effects of human breast fibroblasts on growth and 17 beta-estradiol dehydrogenase activity of MCF-7 cells in culture

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Synthesis and secretion of platelet-derived growth factor by human breast cancer cell lines

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

The distribution of secondary growths in cancer of the breast. 1889

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Cell surface glycoprotein of reactive stromal fibroblasts as a potential antibody target in human epithelial cancers

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Epithelial-mesenchymal transition in breast cancer lines is mediated through PDGF-D released by tissue-resident stem cells

12 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Molecular pathways: osteoclast-dependent and osteoclast-independent roles of the RANKL/RANK/OPG pathway in tumorigenesis and metastasis

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Human solid tumors contain high endothelial venules: association with T- and B-lymphocyte infiltration and favorable prognosis in breast cancer.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Cancer-associated adipocytes promotes breast tumor radioresistance.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Tumor-infiltrating CD8+ lymphocytes predict clinical outcome in breast cancer.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Adipose tissue-derived stem cells differentiate into carcinoma-associated fibroblast-like cells under the influence of tumor-derived factors.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Periprostatic adipose tissue as a modulator of prostate cancer aggressiveness

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Inhibition of bone and muscle metastases of lung cancer cells by a decrease in the number of monocytes/macrophages

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Expression of p21waf1/Cip1 in stromal fibroblasts of primary breast tumors.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Extracellular matrix signature identifies breast cancer subgroups with different clinical outcome.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Breast cancer DNA methylation profiles in cancer cells and tumor stroma: association with HER-2/neu status in primary breast cancer.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Selective evolution of stromal mesenchyme with p53 loss in response to epithelial tumorigenesis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Evidence for nonautonomous effect of p53 tumor suppressor in carcinogenesis.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Adipocyte-secreted factors synergistically promote mammary tumorigenesis through induction of anti-apoptotic transcriptional programs and proto-oncogene stabilization

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Breast stroma plays a dominant regulatory role in breast epithelial growth and differentiation: implications for tumor development and progression.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Human breast carcinoma desmoplasia is PDGF initiated.

25 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4432936

Molecular portraits of human breast tumours

25 September 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-012-9415-3

Direct involvement of breast tumor fibroblasts in the modulation of tamoxifen sensitivity

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-012-9415-3

Clonal Mutations in the Cancer-Associated Fibroblasts: The Case against Genetic Coevolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-012-9415-3

Discovery of Endothelial to Mesenchymal Transition as a Source for Carcinoma-Associated Fibroblasts

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS10555-012-9415-3

Highly proliferative fibroblasts forming fibrotic focus govern metastasis of invasive ductal carcinoma of the breast

21 January 2018

1 reference

12 December 2020

Expression of vascular endothelial growth factor by macrophages is up-regulated in poorly vascularized areas of breast carcinomas

1 reference

12 December 2020

Association of macrophage infiltration with angiogenesis and prognosis in invasive breast carcinoma

1 reference

12 December 2020

Transforming growth factor-beta1 induces desmoplasia in an experimental model of human pancreatic carcinoma

1 reference

12 December 2020

High miR-21 expression in breast cancer associated with poor disease-free survival in early stage disease and high TGF-beta1

1 reference

12 December 2020

Human breast cancer-associated fibroblasts (CAFs) show caveolin-1 downregulation and RB tumor suppressor functional inactivation: Implications for the response to hormonal therapy

1 reference

12 December 2020

Identification of fibroblast heterogeneity in the tumor microenvironment

1 reference

12 December 2020

The prognostic significance of tumor-associated stroma in invasive breast carcinoma

1 reference

12 December 2020

10.1007/S10555-012-9415-3

Identifiers

DOI

1 reference

9 August 2017

1 reference

9 August 2017

1 reference