Inferences, questions and possibilities in Toll-like receptor signalling (Q35829752)

10 August 2017

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title

Inferences, questions and possibilities in Toll-like receptor signalling (English)

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10 August 2017

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1

Bruce Beutler

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10 August 2017

language of work or name

English

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publication date

1 July 2004

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10 August 2017

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10 August 2017

volume

430

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10 August 2017

issue

6996

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10 August 2017

page(s)

257-263

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Establishment of dorsal-ventral polarity in the Drosophila embryo: the induction of polarity by the Toll gene product

10 August 2017

cites work

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Forward genetic dissection of afferent immunity: the role of TIR adapter proteins in innate and adaptive immune responses

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Toll-like receptors: critical proteins linking innate and acquired immunity

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Activation of Toll-like receptor-2 by glycosylphosphatidylinositol anchors from a protozoan parasite

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Impaired production of proinflammatory cytokines and host resistance to acute infection with Trypanosoma cruzi in mice lacking functional myeloid differentiation factor 88.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

The Toll-like receptor 2 is recruited to macrophage phagosomes and discriminates between pathogens.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Differential roles of TLR2 and TLR4 in recognition of gram-negative and gram-positive bacterial cell wall components

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

A toll-like receptor that prevents infection by uropathogenic bacteria

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Toll-like receptor (TLR) 2 and TLR4 are essential for Aspergillus-induced activation of murine macrophages

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Identification of Lps2 as a key transducer of MyD88-independent TIR signalling

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Toll-like receptor 9-mediated recognition of Herpes simplex virus-2 by plasmacytoid dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Species-specific recognition of single-stranded RNA via toll-like receptor 7 and 8

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Recognition of single-stranded RNA viruses by Toll-like receptor 7

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Nods, Nalps and Naip: intracellular regulators of bacterial-induced inflammation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Vital involvement of a natural killer cell activation receptor in resistance to viral infection.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Upregulation of costimulatory molecules induced by lipopolysaccharide and double-stranded RNA occurs by Trif-dependent and Trif-independent pathways

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Toll-like receptors control activation of adaptive immune responses

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Identity of tumour necrosis factor and the macrophage-secreted factor cachectin

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Passive immunization against cachectin/tumor necrosis factor protects mice from lethal effect of endotoxin

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Interferon gamma receptor deficient mice are resistant to endotoxic shock

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Interleukin-12 is required for interferon-gamma production and lethality in lipopolysaccharide-induced shock in mice.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Randomised double-blind comparison of chimeric monoclonal antibody to tumour necrosis factor alpha (cA2) versus placebo in rheumatoid arthritis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Successful treatment of active ankylosing spondylitis with the anti-tumor necrosis factor alpha monoclonal antibody infliximab

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Treatment of Crohn's disease with anti-tumor necrosis factor chimeric monoclonal antibody (cA2).

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Etanercept for severe psoriasis and psoriatic arthritis: observations on combination therapy

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Drosophila immune deficiency (IMD) is a death domain protein that activates antibacterial defense and can promote apoptosis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Structure and expression of the attacin genes in Hyalophora cecropia

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Insect immunity: the diptericin promoter contains multiple functional regulatory sequences homologous to mammalian acute-phase response elements.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

The Rel protein DIF mediates the antifungal but not the antibacterial host defense in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Kappa B-type enhancers are involved in lipopolysaccharide-mediated transcriptional activation of the tumor necrosis factor alpha gene in primary macrophages

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Endotoxin-responsive sequences control cachectin/tumor necrosis factor biosynthesis at the translational level

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

TRADD-TRAF2 and TRADD-FADD interactions define two distinct TNF receptor 1 signal transduction pathways

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

TRAF2-mediated activation of NF-kappa B by TNF receptor 2 and CD40

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Transient activation of NF-kappaB through a TAK1/IKK kinase pathway by TGF-beta1 inhibits AP-1/SMAD signaling and apoptosis: implications in liver tumor formation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

IkappaB kinases phosphorylate NF-kappaB p65 subunit on serine 536 in the transactivation domain

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Functional interactions of transforming growth factor beta-activated kinase 1 with IkappaB kinases to stimulate NF-kappaB activation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Calcineurin mediates human tumor necrosis factor alpha gene induction in stimulated T and B cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

CD28 mediates a potent costimulatory signal for rapid degradation of IkappaBbeta which is associated with accelerated activation of various NF-kappaB/Rel heterodimers

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Mixed-lineage kinase 3 delivers CD3/CD28-derived signals into the IkappaB kinase complex

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Protein kinase C-theta participates in NF-kappaB activation induced by CD3-CD28 costimulation through selective activation of IkappaB kinase beta

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Identifying the MAGUK protein Carma-1 as a central regulator of humoral immune responses and atopy by genome-wide mouse mutagenesis.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

CD28 delivers a unique signal leading to the selective recruitment of RelA and p52 NF-kappaB subunits on IL-8 and Bcl-xL gene promoters.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

CD3/CD28 costimulation-induced NF-kappaB activation is mediated by recruitment of protein kinase C-theta, Bcl10, and IkappaB kinase beta to the immunological synapse through CARMA1

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Activation of autoreactive B cells by CpG dsDNA

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Toll-like receptors and activation of autoreactive B cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Physical contact between lipopolysaccharide and toll-like receptor 4 revealed by genetic complementation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

CD14-dependent internalization and metabolism of extracellular phosphatidylinositol by monocytes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Isolation of the thrombospondin membrane receptor

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

CD36 mediates the In vitro inhibitory effects of thrombospondin-1 on endothelial cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

CD36 mediates the innate host response to beta-amyloid

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Thrombospondin-1 is a major activator of TGF-beta1 in vivo

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

ALLERGIC IRRITABILITY : THE FORMATION OF ANTI-SHEEP HEMOLYTIC AMBOCEPTOR IN THE NORMAL AND TUBERCULOUS GUINEA PIG.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Effect of meningococcal endotoxin on the immune response

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Type i interferons potently enhance humoral immunity and can promote isotype switching by stimulating dendritic cells in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Links between innate and adaptive immunity via type I interferon

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Selective contribution of IFN-alpha/beta signaling to the maturation of dendritic cells induced by double-stranded RNA or viral infection

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Antitumor applications of stimulating toll-like receptor 9 with CpG oligodeoxynucleotides

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

CpG-DNA aided cross-presentation of soluble antigens by dendritic cells

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Therapeutic targeting of Toll-like receptors for inflammatory and infectious diseases.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

DNA-Based immunization for asthma

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Critical role of the Toll-like receptor signal adaptor protein MyD88 in acute allograft rejection

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Efficacy and safety of recombinant human activated protein C for severe sepsis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Effect of treatment with low doses of hydrocortisone and fludrocortisone on mortality in patients with septic shock

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Assay of locus-specific genetic load implicates rare Toll-like receptor 4 mutations in meningococcal susceptibility

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

A Common Dominant TLR5 Stop Codon Polymorphism Abolishes Flagellin Signaling and Is Associated with Susceptibility to Legionnaires' Disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

E5531, a synthetic non-toxic lipid A derivative blocks the immunobiological activities of lipopolysaccharide

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

A low molecular weight mimic of the Toll/IL-1 receptor/resistance domain inhibits IL-1 receptor-mediated responses

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Severe impairment of interleukin-1 and Toll-like receptor signalling in mice lacking IRAK-4

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

TRAM is specifically involved in the Toll-like receptor 4-mediated MyD88-independent signaling pathway

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Poly(I-C)-induced Toll-like receptor 3 (TLR3)-mediated activation of NFkappa B and MAP kinase is through an interleukin-1 receptor-associated kinase (IRAK)-independent pathway employing the signaling components TLR3-TRAF6-TAK1-TAB2-PKR

1 reference

https://api.crossref.org/works/10.1038%2FNATURE02761

7 January 2021

Insect immunity: developmental and inducible activity of the Drosophila diptericin promoter

1 reference

11 October 2022

https://opencitations.net/index/coci/api/v1/references/10.1038/NATURE02761

Identifiers

DOI

10.1038/NATURE02761

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Dimensions Publication ID

10 August 2017

1023553503

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