Lamin B1 loss is a senescence-associated biomarker. (Q35998585)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22496421%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

title

Lamin B1 loss is a senescence-associated biomarker (English)

1 reference

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28 January 2020

0 references

3

1 reference

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28 January 2020

4

Judith Campisi

1 reference

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28 January 2020

author name string

Adam Freund

series ordinal

1

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28 January 2020

Remi-Martin Laberge

series ordinal

2

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28 January 2020

publication date

11 April 2012

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Molecular Biology of the Cell

28 January 2020

published in

1 reference

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28 January 2020

volume

23

1 reference

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28 January 2020

issue

11

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28 January 2020

page(s)

2066-2075

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Oxidative stress induces an ATM-independent senescence pathway through p38 MAPK-mediated lamin B1 accumulation

28 January 2020

cites work

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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2 October 2017

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The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing

2 October 2017

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2 October 2017

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Ionizing radiation-induced long-term expression of senescence markers in mice is independent of p53 and immune status

2 October 2017

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Diseases of the nuclear envelope

2 October 2017

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A human-like senescence-associated secretory phenotype is conserved in mouse cells dependent on physiological oxygen

2 October 2017

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Feedback between p21 and reactive oxygen production is necessary for cell senescence

2 October 2017

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2 October 2017

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2 October 2017

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Persistent DNA damage signalling triggers senescence-associated inflammatory cytokine secretion.

2 October 2017

1 reference

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p38alpha and p38gamma mediate oncogenic ras-induced senescence through differential mechanisms

2 October 2017

1 reference

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The A- and B-type nuclear lamin networks: microdomains involved in chromatin organization and transcription

2 October 2017

1 reference

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Senescence-associated secretory phenotypes reveal cell-nonautonomous functions of oncogenic RAS and the p53 tumor suppressor

2 October 2017

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Senescence of activated stellate cells limits liver fibrosis

2 October 2017

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Cellular senescence and organismal aging

2 October 2017

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Nutlin-3a activates p53 to both down-regulate inhibitor of growth 2 and up-regulate mir-34a, mir-34b, and mir-34c expression, and induce senescence

2 October 2017

1 reference

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Nuclear lamins: major factors in the structural organization and function of the nucleus and chromatin

2 October 2017

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Free radicals and senescence

2 October 2017

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Cellular senescence: when bad things happen to good cells

2 October 2017

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The nuclear lamina. Both a structural framework and a platform for genome organization

2 October 2017

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Alterations to nuclear architecture and genome behavior in senescent cells

2 October 2017

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Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas

2 October 2017

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Molecular dissection of formation of senescence-associated heterochromatin foci

2 October 2017

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Accumulation of senescent cells in mitotic tissue of aging primates

2 October 2017

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Secretion of vascular endothelial growth factor by primary human fibroblasts at senescence

2 October 2017

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Lamin A-dependent nuclear defects in human aging

2 October 2017

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Senescence-associated beta-galactosidase is lysosomal beta-galactosidase

2 October 2017

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Prelamin A and lamin A appear to be dispensable in the nuclear lamina

2 October 2017

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Stromal-epithelial interactions in aging and cancer: senescent fibroblasts alter epithelial cell differentiation

2 October 2017

1 reference

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Human cell senescence as a DNA damage response.

2 October 2017

1 reference

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Ink4a/Arf expression is a biomarker of aging

2 October 2017

1 reference

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The p16INK4a-RB pathway: molecular link between cellular senescence and tumor suppression

2 October 2017

1 reference

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Lamin B1 is required for mouse development and nuclear integrity

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364172

Cellular senescence, an unpopular yet trustworthy tumor suppressor mechanism

2 October 2017

1 reference

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Reversal of human cellular senescence: roles of the p53 and p16 pathways

2 October 2017

1 reference

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Oxygen sensitivity severely limits the replicative lifespan of murine fibroblasts

2 October 2017

1 reference

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Rb-mediated heterochromatin formation and silencing of E2F target genes during cellular senescence

2 October 2017

1 reference

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Recurrent de novo point mutations in lamin A cause Hutchinson–Gilford progeria syndrome

2 October 2017

1 reference

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Lamin a truncation in Hutchinson-Gilford progeria.

2 October 2017

1 reference

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Mitogen-activated protein kinase p38 defines the common senescence-signalling pathway

2 October 2017

1 reference

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Sequential activation of the MEK-extracellular signal-regulated kinase and MKK3/6-p38 mitogen-activated protein kinase pathways mediates oncogenic ras-induced premature senescence

2 October 2017

1 reference

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Nuclear lamins: building blocks of nuclear architecture

2 October 2017

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Identification of essential genes in cultured mammalian cells using small interfering RNAs.

2 October 2017

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Multiple roles of the tumor suppressor p53.

2 October 2017

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Senescent fibroblasts promote epithelial cell growth and tumorigenesis: a link between cancer and aging

2 October 2017

1 reference

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A- and B-type lamins are differentially expressed in normal human tissues

2 October 2017

1 reference

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The structural basis for the specificity of pyridinylimidazole inhibitors of p38 MAP kinase

2 October 2017

1 reference

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Oncogenic ras provokes premature cell senescence associated with accumulation of p53 and p16INK4a

2 October 2017

1 reference

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Lamin proteolysis facilitates nuclear events during apoptosis

2 October 2017

1 reference

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Efficient transfer, integration, and sustained long-term expression of the transgene in adult rat brains injected with a lentiviral vector

2 October 2017

1 reference

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MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364172

Structural organization of the human gene encoding nuclear lamin A and nuclear lamin C

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364172

SB 203580 is a specific inhibitor of a MAP kinase homologue which is stimulated by cellular stresses and interleukin-1

2 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364172

A biomarker that identifies senescent human cells in culture and in aging skin in vivo

2 October 2017

1 reference

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The nuclear lamins. A multigene family of proteins in evolution and differentiation

2 October 2017

1 reference

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The DNA damage signaling pathway is a critical mediator of oncogene-induced senescence.

2 October 2017

1 reference

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Expression of the p16INK4a tumor suppressor versus other INK4 family members during mouse development and aging.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364172

Pyridinyl imidazole inhibitors of p38 mitogen-activated protein kinase bind in the ATP site

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364172

Degradation of lamin B1 precedes oligonucleosomal DNA fragmentation in apoptotic thymocytes and isolated thymocyte nuclei.

11 July 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364172

Real-time in vivo imaging of p16gene expression: a new approach to study senescence stress signaling in living animals

11 July 2018

1 reference

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Transcriptional repression mediated by repositioning of genes to the nuclear lamina

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364172

Induction of p53-dependent senescence by the MDM2 antagonist nutlin-3a in mouse cells of fibroblast origin.

23 September 2018

1 reference

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Caspase-3 is required in the apoptotic disintegration of the nuclear matrix

23 September 2018

1 reference

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Raf-1-induced growth arrest in human mammary epithelial cells is p16-independent and is overcome in immortal cells during conversion

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364172

Early molecular changes in irradiated aortic endothelium

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364172

The nuclear envelope lamina is reversibly depolymerized during mitosis

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364172

Replicative senescence in normal liver, chronic hepatitis C, and hepatocellular carcinomas

23 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3364172

DNA damage response and cellular senescence in tissues of aging mice

14 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22496421

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1091/MBC.E11-10-0884

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22496421%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22496421%20AND%20SRC:MED&resulttype=core&format=json

28 January 2020

PubMed publication ID

22496421

1 reference