Molecular pathogenesis of oligodendroglial tumors (Q36021563)

11 August 2017

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title

Molecular pathogenesis of oligodendroglial tumors (English)

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11 August 2017

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2

Andreas von Deimling

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Pieter Wesseling

series ordinal

3

object named as

Pieter Wesseling

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11 August 2017

Judith W M Jeuken

1

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11 August 2017

publication date

1 November 2004

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Journal of Neuro-Oncology

11 August 2017

published in

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11 August 2017

volume

70

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11 August 2017

issue

2

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11 August 2017

page(s)

161-181

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Oligodendrogliomas with neurocytic differentiation. A report of 4 cases with diagnostic and histogenetic implications

11 August 2017

cites work

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Molecular heterogeneity of oligodendrogliomas suggests alternative pathways in tumor progression

21 January 2018

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Expression of the Oligodendroglial Lineage-Associated Markers Olig1 and Olig2 in Different Types of Human Gliomas

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Distinct expression pattern of microtubule-associated protein-2 in human oligodendrogliomas and glial precursor cells

21 January 2018

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MAP-2e, a novel MAP-2 isoform, is expressed in gliomas and delineates tumor architecture and patterns of infiltration

21 January 2018

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Genetic signature of oligoastrocytomas correlates with tumor location and denotes distinct molecular subsets

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Astrocytes give rise to oligodendrogliomas and astrocytomas after gene transfer of polyoma virus middle T antigen in vivo

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Loss of heterozygosity on chromosome 19 in secondary glioblastomas.

21 January 2018

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Identification of the small interstitial deletion at chromosome band 1p34-p35 and its association with poor outcome in oligodendroglial tumors

21 January 2018

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12 December 2020

Clonality of oligoastrocytomas.

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12 December 2020

Mutation and cancer: statistical study of retinoblastoma

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12 December 2020

Molecular genetic aspects of oligodendrogliomas including analysis by comparative genomic hybridization

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12 December 2020

Characterization of gene expression profiles associated with glioma progression using oligonucleotide-based microarray analysis and real-time reverse transcription-polymerase chain reaction

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12 December 2020

Homozygous deletions of the CDKN2C/p18INK4C gene on the short arm of chromosome 1 in anaplastic oligodendrogliomas

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12 December 2020

Glioblastomas with an oligodendroglial component: a pathological and molecular study

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12 December 2020

Recent developments in the molecular characterization and treatment of oligodendroglial tumors

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12 December 2020

Alterations of chromosome arms 1p and 19q as predictors of survival in oligodendrogliomas, astrocytomas, and mixed oligoastrocytomas.

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12 December 2020

Genomic organization and mutation analysis of p73 in oligodendrogliomas with chromosome 1 p-arm deletions

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12 December 2020

p73: Friend or foe in tumorigenesis

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12 December 2020

Preferential loss of paternal 19q, but not 1p, alleles in oligodendrogliomas.

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12 December 2020

OLIG-1 and 2 gene expression and oligodendroglial tumours

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12 December 2020

Temozolomide for recurrent high-grade glioma

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12 December 2020

Mapping of the chromosome 19 q-arm glioma tumor suppressor gene using fluorescence in situ hybridization and novel microsatellite markers

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12 December 2020

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12 December 2020

Genetic aberrations in oligodendroglial tumours: an analysis using comparative genomic hybridization (CGH)

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12 December 2020

Molecular genetic evidence for subtypes of oligoastrocytomas.

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12 December 2020

Comparative genomic hybridization: practical guidelines

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12 December 2020

Impact of genotype and morphology on the prognosis of glioblastoma

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12 December 2020

CDKN2 (p16/MTS1) gene deletion or CDK4 amplification occurs in the majority of glioblastomas.

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12 December 2020

hRAD54 gene and 1p high-resolution deletion-mapping analyses in oligodendrogliomas

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12 December 2020

Tumor location and growth pattern correlate with genetic signature in oligodendroglial neoplasms

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12 December 2020

Molecular genetic analysis of oligodendroglial tumors shows preferential allelic deletions on 19q and 1p

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12 December 2020

Subtyping of oligo-astrocytic tumours by comparative genomic hybridization.

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12 December 2020

Oligodendroglioma: the Rotterdam-Dijkzigt experience

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12 December 2020

Pediatric oligodendrogliomas: a study of molecular alterations on 1p and 19q using fluorescence in situ hybridization.

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12 December 2020

Chromosome 1p allelic loss by fluorescence in situ hybridization is not observed in dysembryoplastic neuroepithelial tumors

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12 December 2020

Deletion mapping of chromosome 19 in human gliomas.

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12 December 2020

Allelic loss of chromosome 1p and radiotherapy plus chemotherapy in patients with oligodendrogliomas.

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12 December 2020

Mutation analysis of the p73 gene in nonastrocytic brain tumours

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12 December 2020

Oligodendrogliomas: reproducibility and prognostic value of histologic diagnosis and grading

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12 December 2020

Localization of common deletion regions on 1p and 19q in human gliomas and their association with histological subtype

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12 December 2020

Correlation of cytogenetic analysis and loss of heterozygosity studies in human diffuse astrocytomas and mixed oligo‐astrocytomas

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12 December 2020

Genomic imprinting and cancer

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12 December 2020

Identification of subgroups of high-grade oligodendroglial tumors by comparative genomic hybridization.

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12 December 2020

Safety and efficacy of temozolomide in patients with recurrent anaplastic oligodendrogliomas after standard radiotherapy and chemotherapy.

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12 December 2020

Loss of imprinting and allele switching of p73 in renal cell carcinoma

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12 December 2020

Transcriptional inactivation of TP73 expression in oligodendroglial tumors

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12 December 2020

Activation of p73 silent allele in lung cancer.

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12 December 2020

Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice

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12 December 2020

Amplification and overexpression of MDM2 in primary (de novo) glioblastomas.

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12 December 2020

Detection of 1p and 19q loss in oligodendroglioma by quantitative microsatellite analysis, a real-time quantitative polymerase chain reaction assay

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12 December 2020

Chromosomal abnormalities in glioblastoma multiforme by comparative genomic hybridization: correlation with radiation treatment outcome.

1 reference

12 December 2020

Correlation between genetic alteration and long‐term clinical outcome of patients with oligodendroglial tumors, with identification of a consistent region of deletion on chromosome arm 1p

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12 December 2020

Oligodendroglioma: toward molecular definitions in diagnostic neuro-oncology

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12 December 2020

Influence of unrecognized molecular heterogeneity on randomized clinical trials

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12 December 2020

Identification of two distinct deleted regions on the short arm of chromosome 1 and rare mutation of the CDKN2C gene from 1p32 in oligodendroglial tumors

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12 December 2020

Allelic loss at 1p and 19q frequently occurs in association and may represent early oncogenic events in oligodendroglial tumors

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12 December 2020

Molecular subtypes of anaplastic oligodendroglioma: implications for patient management at diagnosis.

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12 December 2020

Chromosomal anomalies in oligodendroglial tumors are correlated with clinical features.

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12 December 2020

Specific genetic predictors of chemotherapeutic response and survival in patients with anaplastic oligodendrogliomas

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12 December 2020

Haploinsufficiency for tumor suppression: the hazards of being single and living a long time

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12 December 2020

Region-specific loss of heterozygosity on chromosome 19 is related to the morphologic type of human glioma

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12 December 2020

A glial progenitor cell that develops in vitro into an astrocyte or an oligodendrocyte depending on culture medium

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12 December 2020

Molecular diagnosis of oligodendroglioma in paraffin sections

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12 December 2020

Plastic phenotype of human oligodendroglial tumour cells in vitro

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12 December 2020

Epigenetic silencing of PEG3 gene expression in human glioma cell lines

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12 December 2020

Long survival and therapeutic responses in patients with histologically disparate high-grade gliomas demonstrating chromosome 1p loss.

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12 December 2020

Detection of multiple gene amplifications in glioblastoma multiforme using array-based comparative genomic hybridization

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12 December 2020

Oligodendroglial tumors frequently demonstrate hypermethylation of the CDKN2A (MTS1, p16INK4a), p14ARF, and CDKN2B (MTS2, p15INK4b) tumor suppressor genes.

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12 December 2020

No preferential loss of paternal 19q alleles in oligodendroglial tumors

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12 December 2020

Gene expression profiling with oligonucleotide microarrays distinguishes World Health Organization grade of oligodendrogliomas.

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12 December 2020

Chromosomal imbalances in primary oligodendroglial tumors and their recurrences: clues about malignant progression detected using comparative genomic hybridization

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12 December 2020

Gene expression profiling identifies molecular subtypes of gliomas

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12 December 2020

Tumour suppressor activity of human imprinted gene PEG3 in a glioma cell line

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12 December 2020

Improving diagnostic accuracy and interobserver concordance in the classification and grading of primary gliomas

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12 December 2020

Refined deletion mapping of the chromosome 19q glioma tumor suppressor gene to the D19S412-STD interval.

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12 December 2020

Transcript map of the 3.7-Mb D19S112-D19S246 candidate tumor suppressor region on the long arm of chromosome 19.

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12 December 2020

The importance of genomic copy number changes in the prognosis of glioblastoma multiforme

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12 December 2020

Morphologic and molecular genetic aspects of oligodendroglial neoplasms

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12 December 2020

P18 tumor suppressor gene and progression of oligodendrogliomas to anaplasia.

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12 December 2020

Measurement of DNA copy number at microsatellite loci using quantitative PCR analysis

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12 December 2020

Oligodendrocyte lineage genes (OLIG) as molecular markers for human glial brain tumors

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12 December 2020

Phenotype versus genotype correlation in oligodendrogliomas and low-grade diffuse astrocytomas

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12 December 2020

Molecular analysis of chromosome 1 abnormalities in human gliomas reveals frequent loss of 1p in oligodendroglial tumors

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12 December 2020

Screening for loss of heterozygosity and microsatellite instability in oligodendrogliomas

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12 December 2020

Lack of p16INK4 or retinoblastoma protein (pRb), or amplification-associated overexpression of cdk4 is observed in distinct subsets of malignant glial tumors and cell lines

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12 December 2020

Ancillary FISH analysis for 1p and 19q status: preliminary observations in 287 gliomas and oligodendroglioma mimics

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12 December 2020

Losses of chromosomal arms 1p and 19q in the diagnosis of oligodendroglioma. A study of paraffin-embedded sections

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12 December 2020

What is an oligodendroglioma?

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12 December 2020

CDKN2/p16 or RB alterations occur in the majority of glioblastomas and are inversely correlated.

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12 December 2020

Molecular genetic alterations in glioblastomas with oligodendroglial component.

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12 December 2020

Central neurocytomas are genetically distinct from oligodendrogliomas and neuroblastomas.

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12 December 2020

Concurrent inactivation of RB1 and TP53 pathways in anaplastic oligodendrogliomas.

1 reference

12 December 2020

Comprehensive allelotype and genetic anaysis of 466 human nervous system tumors

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12 December 2020

Second-line chemotherapy with temozolomide in recurrent oligodendroglioma after PCV (procarbazine, lomustine and vincristine) chemotherapy: EORTC Brain Tumor Group phase II study 26972.

1 reference

12 December 2020

Cytogenetic and loss of heterozygosity studies in ependymomas, pilocytic astrocytomas, and oligodendrogliomas

1 reference

12 December 2020

Evidence for a tumor suppressor gene on chromosome 19q associated with human astrocytomas, oligodendrogliomas, and mixed gliomas

1 reference

12 December 2020

Fluorescent in situ hybridization on isolated tumor cell nuclei: a sensitive method for 1p and 19q deletion analysis in paraffin-embedded oligodendroglial tumor specimens

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12 December 2020

Gene silencing in cancer in association with promoter hypermethylation

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12 December 2020

OLIG2 as a specific marker of oligodendroglial tumour cells.

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12 December 2020

Chemotherapy for the treatment of oligodendroglial tumors

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12 December 2020

An integrated metric physical map of human chromosome 19.

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12 December 2020

Genetic analysis of glioblastoma multiforme provides evidence for subgroups within the grade.

1 reference

12 December 2020

Methylation of the p73 gene in gliomas

1 reference

12 December 2020

Chromosome 19q Deletions in Human Gliomas Overlap Telomeric to D19S219 and May Target a 425 kb Region Centromeric to D19S112

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12 December 2020

Characterization of genomic alterations associated with glioma progression by comparative genomic hybridization.

1 reference

12 December 2020

CDK4 amplification is an alternative mechanism to p16 gene homozygous deletion in glioma cell lines

1 reference

12 December 2020

Association of chromosome 10 losses and negative prognosis in oligoastrocytomas.

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12 December 2020

PDGF autocrine stimulation dedifferentiates cultured astrocytes and induces oligodendrogliomas and oligoastrocytomas from neural progenitors and astrocytes in vivo

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12 December 2020

The putative glioma tumor suppressor gene on chromosome 19q maps between APOC2 and HRC.

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12 December 2020

Single or multiple oligodendroglial lineages: a controversy

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12 December 2020

Gene expression-based classification of malignant gliomas correlates better with survival than histological classification.

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12 December 2020

Clinical evidence of distinct subgroups of astrocytic tumors defined by comparative genomic hybridization.

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12 December 2020

EHD2, EHD3, and EHD4 encode novel members of a highly conserved family of EH domain-containing proteins

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12 December 2020

A transcript map of the chromosome 19q-arm glioma tumor suppressor region

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12 December 2020

Shared allelic losses on chromosomes 1p and 19q suggest a common origin of oligodendroglioma and oligoastrocytoma.

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12 December 2020

Recurrent gain of chromosome arm 7q in low-grade astrocytic tumors studied by comparative genomic hybridization

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12 December 2020

Impact of chromosome 1p status in response of oligodendroglioma to temozolomide: preliminary results

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12 December 2020

Correlation of histology and molecular genetic analysis of 1p, 19q, 10q, TP53, EGFR, CDK4, and CDKN2A in 91 astrocytic and oligodendroglial tumors.

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12 December 2020

Molecular pathways in the formation of gliomas.

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12 December 2020

Monoallelically expressed gene related to p53 at 1p36, a region frequently deleted in neuroblastoma and other human cancers

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12 December 2020

Distinction in gene expression profiles of oligodendrogliomas with and without allelic loss of 1p.

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12 December 2020

10.1007/S11060-004-2748-1

Identifiers

DOI

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11 August 2017

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