Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients. (Q36216535)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26193635%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

title

Alefacept provides sustained clinical and immunological effects in new-onset type 1 diabetes patients (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26193635%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

0 references

10

1 reference

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19 February 2020

Steven Willi

16

1 reference

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19 February 2020

Gerald T Nepom

26

1 reference

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19 February 2020

4

Linda A DiMeglio

1 reference

19 February 2020

12

Carla J Greenbaum

1 reference

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19 February 2020

author name string

Mark R Rigby

1

1 reference

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19 February 2020

Kristina M Harris

2

1 reference

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19 February 2020

Ashley Pinckney

3

1 reference

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19 February 2020

Marc S Rendell

5

1 reference

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19 February 2020

Eric I Felner

6

1 reference

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19 February 2020

Jean M Dostou

7

1 reference

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19 February 2020

Stephen E Gitelman

8

1 reference

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19 February 2020

Kurt J Griffin

9

1 reference

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19 February 2020

Peter A Gottlieb

11

1 reference

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19 February 2020

Nicole A Sherry

13

1 reference

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19 February 2020

Wayne V Moore

14

1 reference

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19 February 2020

Roshanak Monzavi

15

1 reference

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19 February 2020

Philip Raskin

17

1 reference

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19 February 2020

Lynette Keyes-Elstein

18

1 reference

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19 February 2020

S Alice Long

19

1 reference

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19 February 2020

Sai Kanaparthi

20

1 reference

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19 February 2020

Noha Lim

21

1 reference

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19 February 2020

Deborah Phippard

22

1 reference

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19 February 2020

Carol L Soppe

23

1 reference

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19 February 2020

Margret L Fitzgibbon

24

1 reference

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19 February 2020

James McNamara

25

1 reference

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19 February 2020

Mario R Ehlers

27

1 reference

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19 February 2020

language of work or name

English

0 references

publication date

20 July 2015

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26193635%20AND%20SRC:MED&resulttype=core&format=json

Journal of Clinical Investigation

19 February 2020

published in

1 reference

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19 February 2020

volume

125

1 reference

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19 February 2020

issue

8

1 reference

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19 February 2020

page(s)

3285-3296

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26193635%20AND%20SRC:MED&resulttype=core&format=json

Anti-thymocyte globulin/G-CSF treatment preserves β cell function in patients with established type 1 diabetes.

19 February 2020

cites work

1 reference

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PD-L1-driven tolerance protects neurogenin3-induced islet neogenesis to reverse established type 1 diabetes in NOD mice.

1 October 2017

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Low-dose otelixizumab anti-CD3 monoclonal antibody DEFEND-1 study: results of the randomized phase III study in recent-onset human type 1 diabetes

1 October 2017

1 reference

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1 October 2017

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Reduction in CD4 central memory T-cell subset in costimulation modulator abatacept-treated patients with recent-onset type 1 diabetes is associated with slower C-peptide decline

1 October 2017

1 reference

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Prevalence of type 1 and type 2 diabetes among children and adolescents from 2001 to 2009.

1 October 2017

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Targeting of memory T cells with alefacept in new-onset type 1 diabetes (T1DAL study): 12 month results of a randomised, double-blind, placebo-controlled phase 2 trial

1 October 2017

1 reference

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Standards of medical care in diabetes--2014

1 October 2017

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Costimulation modulation with abatacept in patients with recent-onset type 1 diabetes: follow-up 1 year after cessation of treatment

1 October 2017

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Teplizumab (anti-CD3 mAb) treatment preserves C-peptide responses in patients with new-onset type 1 diabetes in a randomized controlled trial: metabolic and immunologic features at baseline identify a subgroup of responders

1 October 2017

1 reference

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Hypoglycemia and diabetes: a report of a workgroup of the American Diabetes Association and the Endocrine Society

1 October 2017

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Interleukin-1 antagonism in type 1 diabetes of recent onset: two multicentre, randomised, double-blind, placebo-controlled trials

1 October 2017

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Rapamycin/IL-2 combination therapy in patients with type 1 diabetes augments Tregs yet transiently impairs β-cell function

1 October 2017

1 reference

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Fall in C-peptide during first 2 years from diagnosis: evidence of at least two distinct phases from composite Type 1 Diabetes TrialNet data

1 October 2017

1 reference

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Rituximab-associated progressive multifocal leukoencephalopathy in rheumatoid arthritis

1 October 2017

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The PD-1 pathway in tolerance and autoimmunity

1 October 2017

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Genetics, pathogenesis and clinical interventions in type 1 diabetes

1 October 2017

1 reference

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No effect of the 1alpha,25-dihydroxyvitamin D3 on beta-cell residual function and insulin requirement in adults with new-onset type 1 diabetes

1 October 2017

1 reference

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Failure to preserve beta-cell function with mycophenolate mofetil and daclizumab combined therapy in patients with new- onset type 1 diabetes

1 October 2017

1 reference

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Etanercept treatment in children with new-onset type 1 diabetes: pilot randomized, placebo-controlled, double-blind study

1 October 2017

1 reference

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C-peptide levels and insulin independence following autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus

1 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623571

Alefacept: its safety profile, off-label uses, and potential as part of combination therapies for psoriasis

1 October 2017

1 reference

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Alefacept (anti-CD2) causes a selective reduction in circulating effector memory T cells (Tem) and relative preservation of central memory T cells (Tcm) in psoriasis

1 October 2017

1 reference

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Novel insight into the agonistic mechanism of alefacept in vivo: differentially expressed genes may serve as biomarkers of response in psoriasis patients

1 October 2017

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Autologous nonmyeloablative hematopoietic stem cell transplantation in newly diagnosed type 1 diabetes mellitus

1 October 2017

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Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway.

1 October 2017

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Insulin needs after CD3-antibody therapy in new-onset type 1 diabetes

1 October 2017

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A single course of anti-CD3 monoclonal antibody hOKT3gamma1(Ala-Ala) results in improvement in C-peptide responses and clinical parameters for at least 2 years after onset of type 1 diabetes

1 October 2017

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Alefacept reduces infiltrating T cells, activated dendritic cells, and inflammatory genes in psoriasis vulgaris

1 October 2017

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The programmed death-1 (PD-1) pathway regulates autoimmune diabetes in nonobese diabetic (NOD) mice

1 October 2017

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Selective targeting of T cell subsets: focus on alefacept - a remittive therapy for psoriasis

1 October 2017

1 reference

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Antithymocyte globulin treatment for patients with recent-onset type 1 diabetes: 12-month results of a randomised, placebo-controlled, phase 2 trial.

1 October 2017

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PD-1, but not PD-L1, expressed by islet-reactive CD4+ T cells suppresses infiltration of the pancreas during type 1 diabetes

29 June 2018

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Specific interaction of lymphocyte function-associated antigen 3 with CD2 can inhibit T cell responses

29 June 2018

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Cyclosporin increases the rate and length of remissions in insulin-dependent diabetes of recent onset. Results of a multicentre double-blind trial.

29 June 2018

1 reference

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Double-blind controlled trial of azathioprine in children with newly diagnosed type I diabetes.

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623571

Efficacy and safety of low-dose otelixizumab anti-CD3 monoclonal antibody in preserving C-peptide secretion in adolescent type 1 diabetes: DEFEND-2, a randomized, placebo-controlled, double-blind, multi-centre study

29 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623571

GAD65 antigen therapy in recently diagnosed type 1 diabetes mellitus.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623571

Four-year metabolic outcome of a randomised controlled CD3-antibody trial in recent-onset type 1 diabetic patients depends on their age and baseline residual beta cell mass.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623571

Incidence of type 1 and type 2 diabetes in adults aged 30-49 years: the population-based registry in the province of Turin, Italy.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623571

Beta-cell function and the development of diabetes-related complications in the diabetes control and complications trial

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623571

Effects of alefacept on health-related quality of life in patients with psoriasis: results from a randomized, placebo-controlled phase II trial.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623571

Treatment of chronic plaque psoriasis by selective targeting of memory effector T lymphocytes.

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623571

Rituximab, B-Lymphocyte Depletion, and Preservation of Beta-Cell Function

22 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4623571

Glycemic Control and Excess Mortality in Type 1 Diabetes

5 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/26193635

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1172/JCI81722

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26193635%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:26193635%20AND%20SRC:MED&resulttype=core&format=json

19 February 2020

PubMed publication ID

26193635

1 reference