Association of PD-1/PD-L axis expression with cytolytic activity, mutational load, and prognosis in melanoma and other solid tumors (Q37474092)

20 August 2017

Association of PD-1/PD-L axis expression with cytolytic activity, mutational load, and prognosis in melanoma and other solid tumors (English)

1 reference

20 August 2017

1

1 reference

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4 June 2020

Joel C Sunshine

3

1 reference

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4 June 2020

11

Charles G Drake

1 reference

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4 June 2020

author name string

Hao Wang

2

1 reference

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4 June 2020

Genevieve J Kaunitz

4

1 reference

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4 June 2020

Tricia R Cottrell

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27837027%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Haiying Xu

6

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27837027%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Jessica Esandrio

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27837027%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Robert A Anders

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27837027%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Leslie Cope

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27837027%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

Drew M Pardoll

10

1 reference

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4 June 2020

Janis M Taube

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27837027%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

language of work or name

English

0 references

publication date

11 November 2016

1 reference

Proceedings of the National Academy of Sciences of the United States of America

20 August 2017

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27837027%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

volume

113

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27837027%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

issue

48

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27837027%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

page(s)

E7769-E7777

1 reference

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B7-H3 and B7-H4 are independent predictors of a poor prognosis in patients with pancreatic cancer

4 June 2020

cites work

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Adaptive resistance to therapeutic PD-1 blockade is associated with upregulation of alternative immune checkpoints.

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Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy.

23 August 2017

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CANCER. The odds of immunotherapy success

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Genomic correlates of response to CTLA-4 blockade in metastatic melanoma

23 August 2017

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Exome sequencing of desmoplastic melanoma identifies recurrent NFKBIE promoter mutations and diverse activating mutations in the MAPK pathway

23 August 2017

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Genomic Classification of Cutaneous Melanoma

23 August 2017

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Co-occurring genomic alterations define major subsets of KRAS-mutant lung adenocarcinoma with distinct biology, immune profiles, and therapeutic vulnerabilities

23 August 2017

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Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung Cancer

23 August 2017

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PD-1 Blockade in Tumors with Mismatch-Repair Deficiency

23 August 2017

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Differential Expression of Immune-Regulatory Genes Associated with PD-L1 Display in Melanoma: Implications for PD-1 Pathway Blockade

23 August 2017

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TIGIT and PD-1 impair tumor antigen-specific CD8⁺ T cells in melanoma patients

23 August 2017

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Characterization of PD-L1 Expression and Associated T-cell Infiltrates in Metastatic Melanoma Samples from Variable Anatomic Sites

23 August 2017

1 reference

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Cancer immunology. Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer

23 August 2017

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Comprehensive genomic characterization of head and neck squamous cell carcinomas

23 August 2017

1 reference

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B7-H1 and B7-H3 are independent predictors of poor prognosis in patients with non-small cell lung cancer

23 August 2017

1 reference

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Molecular and genetic properties of tumors associated with local immune cytolytic activity

23 August 2017

1 reference

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PD-L1 Expression Correlates with Tumor-Infiltrating Lymphocytes and Response to Neoadjuvant Chemotherapy in Breast Cancer

23 August 2017

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Nivolumab for Metastatic Renal Cell Carcinoma: Results of a Randomized Phase II Trial

23 August 2017

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PD-1 blockade induces responses by inhibiting adaptive immune resistance

23 August 2017

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Predictive correlates of response to the anti-PD-L1 antibody MPDL3280A in cancer patients

23 August 2017

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Genetic basis for clinical response to CTLA-4 blockade in melanoma

23 August 2017

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OX40- and CD27-mediated costimulation synergizes with anti-PD-L1 blockade by forcing exhausted CD8+ T cells to exit quiescence

23 August 2017

1 reference

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Nivolumab in previously untreated melanoma without BRAF mutation

23 August 2017

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Comprehensive molecular profiling of lung adenocarcinoma

23 August 2017

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Mechanism of tumor rejection with doublets of CTLA-4, PD-1/PD-L1, or IDO blockade involves restored IL-2 production and proliferation of CD8(+) T cells directly within the tumor microenvironment

23 August 2017

1 reference

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Neo-antigens predicted by tumor genome meta-analysis correlate with increased patient survival

23 August 2017

1 reference

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Protein expression of programmed death 1 ligand 1 and ligand 2 independently predict poor prognosis in surgically resected lung adenocarcinoma

23 August 2017

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Association of PD-1, PD-1 ligands, and other features of the tumor immune microenvironment with response to anti-PD-1 therapy

23 August 2017

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Comprehensive molecular characterization of urothelial bladder carcinoma

23 August 2017

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PD-L1 expression in the Merkel cell carcinoma microenvironment: association with inflammation, Merkel cell polyomavirus and overall survival

23 August 2017

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Programmed death ligand-1 expression in non-small cell lung cancer

23 August 2017

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Innate and adaptive immune cells in the tumor microenvironment

23 August 2017

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Comprehensive molecular characterization of clear cell renal cell carcinoma

23 August 2017

1 reference

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Mutational heterogeneity in cancer and the search for new cancer-associated genes

23 August 2017

1 reference

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Mining exomic sequencing data to identify mutated antigens recognized by adoptively transferred tumor-reactive T cells

23 August 2017

1 reference

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Integrative analysis of complex cancer genomics and clinical profiles using the cBioPortal

23 August 2017

1 reference

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B7-H3 associated with tumor progression and epigenetic regulatory activity in cutaneous melanoma

23 August 2017

1 reference

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MEK162 for patients with advanced melanoma harbouring NRAS or Val600 BRAF mutations: a non-randomised, open-label phase 2 study

23 August 2017

1 reference

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Comprehensive molecular portraits of human breast tumours

23 August 2017

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Comprehensive genomic characterization of squamous cell lung cancers

23 August 2017

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Comprehensive molecular characterization of human colon and rectal cancer

23 August 2017

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Safety, activity, and immune correlates of anti-PD-1 antibody in cancer

23 August 2017

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The cBio cancer genomics portal: an open platform for exploring multidimensional cancer genomics data

23 August 2017

1 reference

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Colocalization of inflammatory response with B7-h1 expression in human melanocytic lesions supports an adaptive resistance mechanism of immune escape

23 August 2017

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The blockade of immune checkpoints in cancer immunotherapy

23 August 2017

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The immune contexture in human tumours: impact on clinical outcome

23 August 2017

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Cancer exome analysis reveals a T-cell-dependent mechanism of cancer immunoediting

23 August 2017

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Immune inhibitory molecules LAG-3 and PD-1 synergistically regulate T-cell function to promote tumoral immune escape

23 August 2017

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Hallmarks of Cancer: The Next Generation

23 August 2017

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Targeting Tim-3 and PD-1 pathways to reverse T cell exhaustion and restore anti-tumor immunity

23 August 2017

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Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma.

23 August 2017

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B7-H3 is a potent inhibitor of human T-cell activation: No evidence for B7-H3 and TREML2 interaction

23 August 2017

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Fine tuning the immune response through B7-H3 and B7-H4

23 August 2017

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Gene-expression signatures in breast cancer

23 August 2017

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Tumor cell and tumor vasculature expression of B7-H3 predict survival in clear cell renal cell carcinoma

23 August 2017

1 reference

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PD-1 is expressed by tumor-infiltrating immune cells and is associated with poor outcome for patients with renal cell carcinoma

23 August 2017

1 reference

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Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer

23 August 2017

1 reference

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Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma

23 August 2017

1 reference

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Tumor B7-H1 is associated with poor prognosis in renal cell carcinoma patients with long-term follow-up.

23 August 2017

1 reference

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The response of autologous T cells to a human melanoma is dominated by mutated neoantigens

23 August 2017

1 reference

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Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer

23 August 2017

1 reference

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Bioconductor: open software development for computational biology and bioinformatics

23 August 2017

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Evolving synergistic combinations of targeted immunotherapies to combat cancer.

23 August 2017

1 reference

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The prognostic value of PD-L1 expression for non-small cell lung cancer patients: a meta-analysis.

6 September 2017

1 reference

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In situ tumor PD-L1 mRNA expression is associated with increased TILs and better outcome in breast carcinomas

6 September 2017

1 reference

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Clinical development of immunostimulatory monoclonal antibodies and opportunities for combination.

6 September 2017

1 reference

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A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1.

6 September 2017

1 reference

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PD-L1 expression is a favorable prognostic factor in early stage non-small cell carcinoma.

28 September 2017

1 reference

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Proliferative activity of intratumoral CD8(+) T-lymphocytes as a prognostic factor in human renal cell carcinoma: clinicopathologic demonstration of antitumor immunity

28 September 2017

1 reference

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Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma

28 September 2017

1 reference

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Orchestration and Prognostic Significance of Immune Checkpoints in the Microenvironment of Primary and Metastatic Renal Cell Cancer

28 September 2017

1 reference

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Expression of programmed cell death 1 ligand 2 (PD-L2) is a distinguishing feature of primary mediastinal (thymic) large B-cell lymphoma and associated with PDCD1LG2 copy gain

28 September 2017

1 reference

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Molecular subtypes of clear cell renal cell carcinoma are associated with sunitinib response in the metastatic setting

28 September 2017

1 reference

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Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer.

26 June 2018

1 reference

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Tumor cell expression of programmed cell death-1 ligand 1 is a prognostic factor for malignant melanoma

2 September 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=5137776

Tumor-associated lymphocytes as an independent predictor of response to neoadjuvant chemotherapy in breast cancer.

2 September 2018

1 reference

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Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer.

2 September 2018

1 reference

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Delivering PD-1 inhibitory signal concomitant with blocking ICOS co-stimulation suppresses lupus-like syndrome in autoimmune BXSB mice

2 September 2018

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PD-1-Expressing Tumor-Infiltrating T Cells Are a Favorable Prognostic Biomarker in HPV-Associated Head and Neck Cancer

2 September 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1607836113

Interim results of an ongoing Phase I, dose escalation study of MGA271 (Fc-optimized humanized anti-B7-H3 monoclonal antibody) in patients with refractory B7-H3-expressing neoplasms or neoplasms whose vasculature expresses B7-H3.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1607836113

Characteristics and Clinical Impacts of the Immune Environments in Colorectal and Renal Cell Carcinoma Lung Metastases: Influence of Tumor Origin

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1607836113

Cox's Regression Model for Counting Processes: A Large Sample Study

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1607836113

Unbiased Recursive Partitioning: A Conditional Inference Framework

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1607836113

Immunohistochemical localization of programmed death-1 ligand-1 (PD-L1) in gastric carcinoma and its clinical significance

21 January 2018

1 reference

12 December 2020

B7-H3 ligand expression by prostate cancer: a novel marker of prognosis and potential target for therapy

1 reference

12 December 2020

Localization and density of immune cells in the invasive margin of human colorectal cancer liver metastases are prognostic for response to chemotherapy

1 reference

12 December 2020

Atezolizumab, an Anti-Programmed Death-Ligand 1 Antibody, in Metastatic Renal Cell Carcinoma: Long-Term Safety, Clinical Activity, and Immune Correlates From a Phase Ia Study

1 reference

12 December 2020

Cutaneous desmoplastic melanoma: reappraisal of morphologic heterogeneity and prognostic factors

1 reference

12 December 2020

Tumor-Expressed B7-H1 and B7-DC in Relation to PD-1+ T-Cell Infiltration and Survival of Patients with Cervical Carcinoma

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1607836113

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27837027%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27837027%20AND%20SRC:MED&resulttype=core&format=json

4 June 2020

PubMed publication ID

27837027

1 reference