Extracellular vesicles: biology and emerging therapeutic opportunities. (Q38098874)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23584393%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

title

Extracellular vesicles: biology and emerging therapeutic opportunities (English)

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28 February 2020

main subject

extracellular vesicle

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2

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28 February 2020

Matthew J. Wood

series ordinal

4

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28 February 2020

Xandra O. Breakefield

series ordinal

3

object named as

Xandra O Breakefield

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28 February 2020

author name string

Samir EL Andaloussi

series ordinal

1

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28 February 2020

publication date

15 April 2013

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Nature Reviews Drug Discovery

28 February 2020

published in

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28 February 2020

volume

12

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28 February 2020

issue

5

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28 February 2020

page(s)

347-357

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Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy.

28 February 2020

cites work

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Fate of the transferrin receptor during maturation of sheep reticulocytes in vitro: Selective externalization of the receptor

31 March 2020

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Embryonic stem cell-derived microvesicles reprogram hematopoietic progenitors: evidence for horizontal transfer of mRNA and protein delivery

31 March 2020

1 reference

Mesenchymal stem cell exosome: a novel stem cell-based therapy for cardiovascular disease

31 March 2020

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Human mesenchymal stem cell-conditioned medium improves cardiac function following myocardial infarction

31 March 2020

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Reduction of myocardial infarct size by human mesenchymal stem cell conditioned medium

31 March 2020

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Primary human keratinocytes externalize stratifin protein via exosomes.

31 March 2020

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Exosomes are released by cultured cortical neurones.

31 March 2020

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Astrocytes and Glioblastoma cells release exosomes carrying mtDNA.

31 March 2020

1 reference

Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense

31 March 2020

1 reference

Proteomic analysis of microglia-derived exosomes: metabolic role of the aminopeptidase CD13 in neuropeptide catabolism

31 March 2020

1 reference

Intercellular transfer of the oncogenic receptor EGFRvIII by microvesicles derived from tumour cells.

31 March 2020

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Glioblastoma microvesicles transport RNA and proteins that promote tumour growth and provide diagnostic biomarkers

31 March 2020

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Endothelial expression of autocrine VEGF upon the uptake of tumor-derived microvesicles containing oncogenic EGFR

31 March 2020

1 reference

Exosomes: immune properties and potential clinical implementations

31 March 2020

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Electron microscopic observations on the excretion of cell-wall material by Vibrio cholerae

31 March 2020

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Virulence and immunomodulatory roles of bacterial outer membrane vesicles

31 March 2020

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B lymphocytes secrete antigen-presenting vesicles

31 March 2020

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Exosome secretion: molecular mechanisms and roles in immune responses

31 March 2020

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Membrane vesicles as conveyors of immune responses

31 March 2020

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Pivotal role of paracrine effects in stem cell therapies in regenerative medicine: can we translate stem cell-secreted paracrine factors and microvesicles into better therapeutic strategies?

31 March 2020

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Microvesicles derived from human adult mesenchymal stem cells protect against ischaemia-reperfusion-induced acute and chronic kidney injury

31 March 2020

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Tissue-factor-bearing microvesicles arise from lipid rafts and fuse with activated platelets to initiate coagulation.

31 March 2020

1 reference

Extracellular vesicles--vehicles that spread cancer genes

31 March 2020

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Transfer of the chemokine receptor CCR5 between cells by membrane-derived microparticles: a mechanism for cellular human immunodeficiency virus 1 infection

31 March 2020

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Exosomes: vehicles for the transfer of toxic proteins associated with neurodegenerative diseases?

31 March 2020

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Cell-produced alpha-synuclein is secreted in a calcium-dependent manner by exosomes and impacts neuronal survival

31 March 2020

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Packaging of prions into exosomes is associated with a novel pathway of PrP processing.

31 March 2020

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Eradication of established murine tumors using a novel cell-free vaccine: dendritic cell-derived exosomes

31 March 2020

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Exosome-mediated transfer of mRNAs and microRNAs is a novel mechanism of genetic exchange between cells

31 March 2020

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Plasma exosomes can deliver exogenous short interfering RNA to monocytes and lymphocytes.

31 March 2020

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Delivery of siRNA to the mouse brain by systemic injection of targeted exosomes

31 March 2020

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Treatment of brain inflammatory diseases by delivering exosome encapsulated anti-inflammatory drugs from the nasal region to the brain

31 March 2020

1 reference

A novel nanoparticle drug delivery system: the anti-inflammatory activity of curcumin is enhanced when encapsulated in exosomes

31 March 2020

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The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins

31 March 2020

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Syndecan-syntenin-ALIX regulates the biogenesis of exosomes

31 March 2020

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Formation and release of arrestin domain-containing protein 1-mediated microvesicles (ARMMs) at plasma membrane by recruitment of TSG101 protein

31 March 2020

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Tumour-derived microvesicles carry several surface determinants and mRNA of tumour cells and transfer some of these determinants to monocytes

31 March 2020

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Human Tumor-Derived Exosomes Selectively Impair Lymphocyte Responses to Interleukin-2

31 March 2020

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Human tumor-derived exosomes down-modulate NKG2D expression.

31 March 2020

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Murine mammary carcinoma exosomes promote tumor growth by suppression of NK cell function

31 March 2020

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Tumor exosomes inhibit differentiation of bone marrow dendritic cells

31 March 2020

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Polymorphonuclear neutrophil-derived ectosomes interfere with the maturation of monocyte-derived dendritic cells

31 March 2020

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Platelet-derived microparticles stimulate proliferation, survival, adhesion, and chemotaxis of hematopoietic cells

31 March 2020

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Tumour-derived microvesicles modulate biological activity of human monocytes

31 March 2020

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Platelet-mediated modulation of adaptive immunity: unique delivery of CD154 signal by platelet-derived membrane vesicles

31 March 2020

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Dendritic cells release HLA-B-associated transcript-3 positive exosomes to regulate natural killer function

31 March 2020

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Emerging role of neuronal exosomes in the central nervous system

31 March 2020

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Release of exosomes from differentiated neurons and its regulation by synaptic glutamatergic activity

31 March 2020

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Hematopoietic stem cells convert into liver cells within days without fusion

31 March 2020

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Alteration of marrow cell gene expression, protein production, and engraftment into lung by lung-derived microvesicles: a novel mechanism for phenotype modulation.

31 March 2020

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Cellular phenotype switching and microvesicles

31 March 2020

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Stable cell fate changes in marrow cells induced by lung-derived microvesicles

31 March 2020

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Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

31 March 2020

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The microvesicle as a vehicle for EMMPRIN in tumor-stromal interactions

31 March 2020

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Tumor-derived microvesicles promote regulatory T cell expansion and induce apoptosis in tumor-reactive activated CD8+ T lymphocytes

31 March 2020

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Activated T cell exosomes promote tumor invasion via Fas signaling pathway

31 March 2020

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Tumor shedding and coagulation

31 March 2020

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Microparticle-associated tissue factor activity: a link between cancer and thrombosis?

31 March 2020

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Tumor vesicle-associated CD147 modulates the angiogenic capability of endothelial cells

31 March 2020

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New mechanism for Notch signaling to endothelium at a distance by Delta-like 4 incorporation into exosomes

31 March 2020

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Microvesicles secreted by macrophages shuttle invasion-potentiating microRNAs into breast cancer cells

31 March 2020

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Functional delivery of viral miRNAs via exosomes

31 March 2020

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High levels of exosomes expressing CD63 and caveolin-1 in plasma of melanoma patients

31 March 2020

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Amedeo Avogadro's cry: what is 1 µg of exosomes?

31 March 2020

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Ceramide triggers budding of exosome vesicles into multivesicular endosomes

31 March 2020

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Cell surface tetraspanin Tspan8 contributes to molecular pathways of exosome-induced endothelial cell activation

31 March 2020

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Rab27a and Rab27b control different steps of the exosome secretion pathway

31 March 2020

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Rab27a supports exosome-dependent and -independent mechanisms that modify the tumor microenvironment and can promote tumor progression

31 March 2020

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Rab11 promotes docking and fusion of multivesicular bodies in a calcium-dependent manner

31 March 2020

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Regulation of exosome secretion by Rab35 and its GTPase-activating proteins TBC1D10A-C.

31 March 2020

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Tumor-derived microvesicles modulate the establishment of metastatic melanoma in a phosphatidylserine-dependent manner.

31 March 2020

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Endothelial progenitor cell derived microvesicles activate an angiogenic program in endothelial cells by a horizontal transfer of mRNA.

31 March 2020

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Human liver stem cell-derived microvesicles accelerate hepatic regeneration in hepatectomized rats

31 March 2020

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Role of exosomes/microvesicles in the nervous system and use in emerging therapies

31 March 2020

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Evidence supporting paracrine hypothesis for Akt-modified mesenchymal stem cell-mediated cardiac protection and functional improvement

31 March 2020

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Paracrine action accounts for marked protection of ischemic heart by Akt-modified mesenchymal stem cells

31 March 2020

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Therapeutic potential of mesenchymal stem cell-derived microvesicles.

31 March 2020

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Mesenchymal stem cell-derived microvesicles protect against acute tubular injury

31 March 2020

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Exosome secreted by MSC reduces myocardial ischemia/reperfusion injury

31 March 2020

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Microvesicles derived from mesenchymal stem cells enhance survival in a lethal model of acute kidney injury

31 March 2020

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Mesenchymal stem cell: an efficient mass producer of exosomes for drug delivery

31 March 2020

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Microvesicles derived from endothelial progenitor cells protect the kidney from ischemia–reperfusion injury by microRNA-dependent reprogramming of resident renal cells

31 March 2020

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Microvesicles derived from endothelial progenitor cells enhance neoangiogenesis of human pancreatic islets.

31 March 2020

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Production and characterization of clinical grade exosomes derived from dendritic cells.

31 March 2020

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Enabling a robust scalable manufacturing process for therapeutic exosomes through oncogenic immortalization of human ESC-derived MSCs

31 March 2020

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Exosomes released from infected macrophages contain Mycobacterium avium glycopeptidolipids and are proinflammatory

31 March 2020

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Hsp70 translocates into the plasma membrane after stress and is released into the extracellular environment in a membrane-associated form that activates macrophages.

31 March 2020

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Heat shock protein 70 surface-positive tumor exosomes stimulate migratory and cytolytic activity of natural killer cells

31 March 2020

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Differential secretion of Fas ligand- or APO2 ligand/TNF-related apoptosis-inducing ligand-carrying microvesicles during activation-induced death of human T cells

31 March 2020

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Exosomes derived from IL-10-treated dendritic cells can suppress inflammation and collagen-induced arthritis

31 March 2020

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Tumor-derived microvesicles induce, expand and up-regulate biological activities of human regulatory T cells (Treg).

31 March 2020

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Microvesicles derived from adult human bone marrow and tissue specific mesenchymal stem cells shuttle selected pattern of miRNAs

31 March 2020

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Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers

31 March 2020

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Unidirectional transfer of microRNA-loaded exosomes from T cells to antigen-presenting cells

31 March 2020

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Mechanism of transfer of functional microRNAs between mouse dendritic cells via exosomes.

31 March 2020

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Multivesicular bodies associate with components of miRNA effector complexes and modulate miRNA activity

31 March 2020

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Secreted monocytic miR-150 enhances targeted endothelial cell migration

31 March 2020

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Exosomes for targeted siRNA delivery across biological barriers.

31 March 2020

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Microvesicle-mediated RNA molecule delivery system using monocytes/macrophages

31 March 2020

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Hepatic cell-to-cell transmission of small silencing RNA can extend the therapeutic reach of RNA interference (RNAi).

31 March 2020

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Examination of mesenchymal stem cell-mediated RNAi transfer to Huntington's disease affected neuronal cells for reduction of huntingtin

31 March 2020

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Rabies virus binding to an acetylcholine receptor alpha-subunit peptide

31 March 2020

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Microvesicle-associated AAV vector as a novel gene delivery system

31 March 2020

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miR-1289 and "Zipcode"-like Sequence Enrich mRNAs in Microvesicles

31 March 2020

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Genetically engineered microvesicles carrying suicide mRNA/protein inhibit schwannoma tumor growth

31 March 2020

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Systemically injected exosomes targeted to EGFR deliver antitumor microRNA to breast cancer cells

31 March 2020

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Exosomes derived from human bone marrow mesenchymal stem cells promote tumor growth in vivo

31 March 2020

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Microvesicles derived from human bone marrow mesenchymal stem cells inhibit tumor growth

31 March 2020

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Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes

31 March 2020

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Thermal- and oxidative stress causes enhanced release of NKG2D ligand-bearing immunosuppressive exosomes in leukemia/lymphoma T and B cells

31 March 2020

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Active Wnt proteins are secreted on exosomes.

31 March 2020

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ARF6-regulated shedding of tumor cell-derived plasma membrane microvesicles

31 March 2020

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Isolation and characterization of exosomes from cell culture supernatants and biological fluids

31 March 2020

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Fas ligand-positive membranous vesicles isolated from sera of patients with oral cancer induce apoptosis of activated T lymphocytes.

31 March 2020

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12 December 2020

Structures of gram-negative cell walls and their derived membrane vesicles

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12 December 2020

Exosome/microvesicle-mediated epigenetic reprogramming of cells

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12 December 2020

Endocytosis and intracellular processing of transferrin and colloidal gold-transferrin in rat reticulocytes: demonstration of a pathway for receptor shedding

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12 December 2020

Exosomes for drug delivery - a novel application for the mesenchymal stem cell

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12 December 2020

Membrane-associated Hsp72 from tumor-derived exosomes mediates STAT3-dependent immunosuppressive function of mouse and human myeloid-derived suppressor cells

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12 December 2020

Identifiers

DOI

10.1038/NRD3978

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:23584393%20AND%20SRC:MED&resulttype=core&format=json

28 February 2020

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