DNA demethylation pathways: Additional players and regulators (Q39012256)

8 September 2017

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title

DNA demethylation pathways: Additional players and regulators (English)

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8 September 2017

1

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8 September 2017

Agnieszka Kolano

2

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8 September 2017

Guo-Liang Xu

series ordinal

3

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8 September 2017

language of work or name

English

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publication date

16 November 2016

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8 September 2017

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8 September 2017

volume

39

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8 September 2017

issue

1

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8 September 2017

page(s)

1-13

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Functions of DNA methylation: islands, start sites, gene bodies and beyond

8 September 2017

cites work

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

The colorful history of active DNA demethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

A replication-dependent passive mechanism modulates DNA demethylation in mouse primordial germ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Replication-coupled passive DNA demethylation for the erasure of genome imprints in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Active DNA demethylation: many roads lead to Rome.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

The role of Tet3 DNA dioxygenase in epigenetic reprogramming by oocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Reprogramming of the paternal genome upon fertilization involves genome-wide oxidation of 5-methylcytosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Hydroxylation of 5-methylcytosine by TET1 promotes active DNA demethylation in the adult brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Neuronal activity-induced Gadd45b promotes epigenetic DNA demethylation and adult neurogenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

TETonic shift: biological roles of TET proteins in DNA demethylation and transcription

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

The mammalian de novo DNA methyltransferases DNMT3A and DNMT3B are also DNA 5-hydroxymethylcytosine dehydroxymethylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

DNA 5-methylcytosine demethylation activities of the mammalian DNA methyltransferases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Direct decarboxylation of 5-carboxylcytosine by DNA C5-methyltransferases.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Active DNA demethylation mediated by DNA glycosylases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

DNA demethylation by DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Thymine DNA glycosylase can rapidly excise 5-formylcytosine and 5-carboxylcytosine: potential implications for active demethylation of CpG sites

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Uracil-DNA Glycosylase UNG Promotes Tet-mediated DNA Demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

TET-mediated oxidation of methylcytosine causes TDG or NEIL glycosylase dependent gene reactivation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Thymine DNA glycosylase is essential for active DNA demethylation by linked deamination-base excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Genome-wide reprogramming in the mouse germ line entails the base excision repair pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Minimal role of base excision repair in TET-induced global DNA demethylation in HEK293T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Active DNA demethylation by Gadd45 and DNA repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

An interplay of the base excision repair and mismatch repair pathways in active DNA demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Recognition and potential mechanisms for replication and erasure of cytosine hydroxymethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Class switch recombination and hypermutation require activation-induced cytidine deaminase (AID), a potential RNA editing enzyme

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Requirement of the activation-induced deaminase (AID) gene for immunoglobulin gene conversion

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

AID mutates E. coli suggesting a DNA deamination mechanism for antibody diversification

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Specific expression of activation-induced cytidine deaminase (AID), a novel member of the RNA-editing deaminase family in germinal center B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Fate mapping for activation-induced cytidine deaminase (AID) marks non-lymphoid cells during mouse development.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Role of activation-induced cytidine deaminase in the development of oral squamous cell carcinoma

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Expression of activation-induced cytidine deaminase in human hepatocytes during hepatocarcinogenesis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Aberrant AID expression and human cancer development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Activation-induced cytidine deaminase (AID) deficiency causes the autosomal recessive form of the Hyper-IgM syndrome (HIGM2)

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Reprogramming towards pluripotency requires AID-dependent DNA demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Establishment of methylation patterns in ES cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Embryonic stem cells induce pluripotency in somatic cell fusion through biphasic reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

A critical role for AID in the initiation of reprogramming to induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

AID stabilizes stem-cell phenotype by removing epigenetic memory of pluripotency genes.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Activation-induced deaminase-coupled DNA demethylation is not crucial for the generation of induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Generation and characterization of induced pluripotent stem cells from Aid-deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

DNA Methylation Dynamics of Germinal Center B Cells Are Mediated by AID

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Differential programming of B cells in AID deficient mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

A comprehensive analysis of the effects of the deaminase AID on the transcriptome and methylome of activated B cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

DNA demethylation in zebrafish involves the coupling of a deaminase, a glycosylase, and gadd45.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

No evidence for AID/MBD4-coupled DNA demethylation in zebrafish embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Genome-wide erasure of DNA methylation in mouse primordial germ cells is affected by AID deficiency.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

AID/APOBEC deaminases disfavor modified cytosines implicated in DNA demethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

AID enzymatic activity is inversely proportional to the size of cytosine C5 orbital cloud

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Methylation protects cytidines from AID-mediated deamination

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Zebrafish AID is capable of deaminating methylated deoxycytidines

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Activation-induced cytidine deaminase deaminates deoxycytidine on single-stranded DNA but requires the action of RNase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Efficient deamination of 5-methylcytosines in DNA by human APOBEC3A, but not by AID or APOBEC3G.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

High frequency mutagenesis by a DNA methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Cytosine-to-uracil deamination by SssI DNA methyltransferase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Processive DNA demethylation via DNA deaminase-induced lesion resolution

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Active demethylation in mouse zygotes involves cytosine deamination and base excision repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Activation-induced cytidine deaminase and active cytidine demethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Cytidine deaminases: AIDing DNA demethylation?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Conversion of 5-methylcytosine to 5-hydroxymethylcytosine in mammalian DNA by MLL partner TET1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

The nuclear DNA base 5-hydroxymethylcytosine is present in Purkinje neurons and the brain

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Tet proteins can convert 5-methylcytosine to 5-formylcytosine and 5-carboxylcytosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Structural insight into substrate preference for TET-mediated oxidation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

TET1, a member of a novel protein family, is fused to MLL in acute myeloid leukemia containing the t(10;11)(q22;q23).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Insights into DNA hydroxymethylation in the honeybee from in-depth analyses of TET dioxygenase.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Structure of a Naegleria Tet-like dioxygenase in complex with 5-methylcytosine DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Biochemical characterization of a Naegleria TET-like oxygenase and its application in single molecule sequencing of 5-methylcytosine.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Prediction of novel families of enzymes involved in oxidative and other complex modifications of bases in nucleic acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Tet3 Reads 5-Carboxylcytosine through Its CXXC Domain and Is a Potential Guardian against Neurodegeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Loss of Tet enzymes compromises proper differentiation of embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Age-dependent levels of 5-methyl-, 5-hydroxymethyl-, and 5-formylcytosine in human and mouse brain tissues

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Dynamic readers for 5-(hydroxy)methylcytosine and its oxidized derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Tet-mediated formation of 5-carboxylcytosine and its excision by TDG in mammalian DNA

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Biochemical reconstitution of TET1-TDG-BER-dependent active DNA demethylation reveals a highly coordinated mechanism

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Tet and TDG mediate DNA demethylation essential for mesenchymal-to-epithelial transition in somatic cell reprogramming.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Mechanisms and models of somatic cell reprogramming

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Replacement of Oct4 by Tet1 during iPSC induction reveals an important role of DNA methylation and hydroxymethylation in reprogramming.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

The combination of Tet1 with Oct4 generates high-quality mouse-induced pluripotent stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Role of Tet proteins in enhancer activity and telomere elongation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

5mC oxidation by Tet2 modulates enhancer activity and timing of transcriptome reprogramming during differentiation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Haploinsufficiency, but not defective paternal 5mC oxidation, accounts for the developmental defects of maternal Tet3 knockouts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Tet1 is dispensable for maintaining pluripotency and its loss is compatible with embryonic and postnatal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Deletion of Tet2 in mice leads to dysregulated hematopoietic stem cells and subsequent development of myeloid malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Combined deficiency of Tet1 and Tet2 causes epigenetic abnormalities but is compatible with postnatal development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

TET-mediated DNA demethylation controls gastrulation by regulating Lefty-Nodal signalling.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Tet3 CXXC Domain and Dioxygenase Activity Cooperatively Regulate Key Genes for Xenopus Eye and Neural Development

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Overlapping Requirements for Tet2 and Tet3 in Normal Development and Hematopoietic Stem Cell Emergence

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Acquired mutations in TET2 are common in myelodysplastic syndromes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Mutation in TET2 in myeloid cancers

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

TET2 gene mutation is a frequent and adverse event in chronic myelomonocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Deamination, oxidation, and C-C bond cleavage reactivity of 5-hydroxymethylcytosine, 5-formylcytosine, and 5-carboxycytosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Essential role for de novo DNA methyltransferase Dnmt3a in paternal and maternal imprinting

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Dnmt3L and the establishment of maternal genomic imprints

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Meiotic and epigenetic aberrations in Dnmt3L-deficient male germ cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Mechanism of the Orotidine 5′-Monophosphate Decarboxylase-Catalyzed Reaction: Importance of Residues in the Orotate Binding Site

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Uracil in DNA--occurrence, consequences and repair

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

5-Formylcytosine alters the structure of the DNA double helix

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Differential stabilities and sequence-dependent base pair opening dynamics of Watson-Crick base pairs with 5-hydroxymethylcytosine, 5-formylcytosine, or 5-carboxylcytosine

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Divergent mechanisms for enzymatic excision of 5-formylcytosine and 5-carboxylcytosine from DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Guanine- 5-carboxylcytosine base pairs mimic mismatches during DNA replication.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Weakened N3 Hydrogen Bonding by 5-Formylcytosine and 5-Carboxylcytosine Reduces Their Base-Pairing Stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Glycosidic Bond Cleavage in DNA Nucleosides: Effect of Nucleobase Damage and Activation on the Mechanism and Barrier.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

How do DNA repair proteins locate damaged bases in the genome?

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Activity and crystal structure of human thymine DNA glycosylase mutant N140A with 5-carboxylcytosine DNA at low pH

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Active and passive demethylation of male and female pronuclear DNA in the mammalian zygote

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Embryonic lethal phenotype reveals a function of TDG in maintaining epigenetic stability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Variant base excision repair proteins: contributors to genomic instability

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Neil DNA glycosylases promote substrate turnover by Tdg during DNA demethylation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

The metabolic syndrome resulting from a knockout of the NEIL1 DNA glycosylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Neil2-null Mice Accumulate Oxidized DNA Bases in the Transcriptionally Active Sequences of the Genome and Are Susceptible to Innate Inflammation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Expression patterns of Neil3 during embryonic brain development and neoplasia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Uracil-DNA glycosylase (UNG)-deficient mice reveal a primary role of the enzyme during DNA replication

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Base damage and single-strand break repair: mechanisms and functional significance of short- and long-patch repair subpathways

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

GADD45 proteins: central players in tumorigenesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Gadd45a promotes DNA demethylation through TDG.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Conserved DNA methylation in Gadd45a(-/-) mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

DNA unwinding produced by site-specific intrastrand cross-links of the antitumor drug cis-diamminedichloroplatinum(II).

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

5-formylcytosine and 5-carboxylcytosine reduce the rate and substrate specificity of RNA polymerase II transcription.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Transcription-coupled nucleotide excision repair in mammalian cells: molecular mechanisms and biological effects

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

The multifaceted mismatch-repair system

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Tet3 and DNA replication mediate demethylation of both the maternal and paternal genomes in mouse zygotes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Tet2 loss leads to increased hematopoietic stem cell self-renewal and myeloid transformation

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Acute loss of TET function results in aggressive myeloid cancer in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Combined Loss of Tet1 and Tet2 Promotes B Cell, but Not Myeloid Malignancies, in Mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

TET2 plays an essential role in erythropoiesis by regulating lineage-specific genes via DNA oxidative demethylation in a zebrafish model

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

A zebrafish model of myelodysplastic syndrome produced through tet2 genomic editing.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

TET2 mutations are associated with specific 5-methylcytosine and 5-hydroxymethylcytosine profiles in patients with chronic myelomonocytic leukemia

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

TET2 Mutations Affect Non-CpG Island DNA Methylation at Enhancers and Transcription Factor-Binding Sites in Chronic Myelomonocytic Leukemia.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Oncometabolite 2-hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Inhibition of α-KG-dependent histone and DNA demethylases by fumarate and succinate that are accumulated in mutations of FH and SDH tumor suppressors

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Ascorbic Acid: Biologic Functions and Relation to Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Vitamin C induces Tet-dependent DNA demethylation and a blastocyst-like state in ES cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Vitamin C promotes widespread yet specific DNA demethylation of the epigenome in human embryonic stem cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Ascorbic acid enhances Tet-mediated 5-methylcytosine oxidation and promotes DNA demethylation in mammals

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Regulation of the Epigenome by Vitamin C

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

NANOG-dependent function of TET1 and TET2 in establishment of pluripotency

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Vitamin C enhances epigenetic modifications induced by 5-azacytidine and cell cycle arrest in the hepatocellular carcinoma cell lines HLE and Huh7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Tet family proteins and 5-hydroxymethylcytosine in development and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Catalysis of three sequential dioxygenase reactions by thymine 7-hydroxylase

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Definitive identification of mammalian 5-hydroxymethyluracil DNA N-glycosylase activity as SMUG1

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

An unexpectedly high excision capacity for mispaired 5-hydroxymethyluracil in human cell extracts

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Tet oxidizes thymine to 5-hydroxymethyluracil in mouse embryonic stem cell DNA.

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Quantification of 5-methylcytosine, 5-hydroxymethylcytosine and 5-carboxylcytosine from the blood of cancer patients by an enzyme-based immunoassay

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Antibody diversification caused by disrupted mismatch repair and promiscuous DNA polymerases

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Mechanism and Stem-Cell Activity of 5-Carboxycytosine Decarboxylation Determined by Isotope Tracing

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

Demethylation of the zygotic paternal genome

21 January 2018

1 reference

https://api.crossref.org/works/10.1002%2FBIES.201600178

21 January 2018

Identifiers

DOI

10.1002/BIES.201600178

1 reference

8 September 2017

1 reference