A novel retinoblastoma therapy from genomic and epigenetic analyses (Q39413689)

11 September 2017

A novel retinoblastoma therapy from genomic and epigenetic analyses (English)

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11 September 2017

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17

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11 September 2017

Justina McEvoy

3

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Claudia A. Benavente

object named as

Claudia A Benavente

2

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Stanley Pounds

object named as

Stanley Pounds

18

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Elaine Mardis

31

object named as

Elaine R Mardis

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11 September 2017

9

Matthew Wilson

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11 September 2017

28

Kerri Ochoa

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11 September 2017

12

Michael Rusch

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11 September 2017

32

Armita Bahrami

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11 September 2017

Jinghui Zhang

1

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11 September 2017

Jacqueline Flores-Otero

4

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11 September 2017

Li Ding

5

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11 September 2017

Xiang Chen

6

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11 September 2017

Anatoly Ulyanov

7

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11 September 2017

Gang Wu

8

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11 September 2017

Jianmin Wang

10

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11 September 2017

Rachel Brennan

11

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11 September 2017

Amity L Manning

13

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11 September 2017

Jing Ma

14

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11 September 2017

John Easton

15

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11 September 2017

Sheila Shurtleff

16

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11 September 2017

Suraj Mukatira

19

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11 September 2017

Pankaj Gupta

20

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11 September 2017

Geoff Neale

21

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11 September 2017

David Zhao

22

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11 September 2017

Charles Lu

23

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11 September 2017

Robert S Fulton

24

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11 September 2017

Lucinda L Fulton

25

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11 September 2017

Xin Hong

26

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11 September 2017

David J Dooling

27

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11 September 2017

Clayton Naeve

29

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11 September 2017

Nicholas J Dyson

30

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11 September 2017

David Ellison

33

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11 September 2017

Richard K Wilson

34

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11 September 2017

James R Downing

35

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11 September 2017

Michael A Dyer

36

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11 September 2017

language of work or name

English

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publication date

11 January 2012

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11 September 2017

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11 September 2017

481

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11 September 2017

7381

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11 September 2017

329-334

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Creative Commons Attribution-NonCommercial-ShareAlike 3.0 Unported

11 September 2017

start time

1 January 2012

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April 2022 Public Data File from Crossref

copyright status

copyrighted

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cites work

Coexpression of normally incompatible developmental pathways in retinoblastoma genesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

Targeting the p53 pathway in retinoblastoma with subconjunctival Nutlin-3a

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

Hallmarks of Cancer: The Next Generation

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

An Oral Spleen Tyrosine Kinase (Syk) Inhibitor for Rheumatoid Arthritis

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

Covalent histone modifications--miswritten, misinterpreted and mis-erased in human cancers

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

Loss of pRB causes centromere dysfunction and chromosomal instability

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

RNAi mediated acute depletion of retinoblastoma protein (pRb) promotes aneuploidy in human primary cells via micronuclei formation.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

Proteomic and genetic approaches identify Syk as an AML target

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

A mechanism linking extra centrosomes to chromosomal instability

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

SWI/SNF deficiency results in aberrant chromatin organization, mitotic failure, and diminished proliferative capacity

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

DNA sequencing of a cytogenetically normal acute myeloid leukaemia genome

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

Mouse models of non-Hodgkin lymphoma reveal Syk as an important therapeutic target

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

Overexpression of Syk tyrosine kinase in peripheral T-cell lymphomas.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

Epigenetic regulation of gene expression by Drosophila Myb and E2F2-RBF via the Myb-MuvB/dREAM complex

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

SYK-dependent tonic B-cell receptor signaling is a rational treatment target in diffuse large B-cell lymphoma

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

A genome-wide RNA interference screen identifies putative chromatin regulators essential for E2F repression

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

One hit, two hits, three hits, more? Genomic changes in the development of retinoblastoma.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

RB acute loss induces centrosome amplification and aneuploidy in murine primary fibroblasts.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

The history of cancer epigenetics

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

Cancer epigenetics comes of age

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

Mutation and cancer: statistical study of retinoblastoma

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

A human DNA segment with properties of the gene that predisposes to retinoblastoma and osteosarcoma

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

Rb inactivation promotes genomic instability by uncoupling cell cycle progression from mitotic control.

11 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

Increased methylation variation in epigenetic domains across cancer types

14 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

The Syk inhibitor fostamatinib disodium (R788) inhibits tumor growth in the Eμ- TCL1 transgenic mouse model of CLL by blocking antigen-dependent B-cell receptor signaling

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

Inhibition of constitutive and BCR-induced Syk activation downregulates Mcl-1 and induces apoptosis in chronic lymphocytic leukemia B cells

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

A detailed analysis of chromosomal changes in heritable and non-heritable retinoblastoma.

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

Spleen tyrosine kinase inhibition prevents chemokine- and integrin-mediated stromal protective effects in chronic lymphocytic leukemia

17 June 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

The tyrosine kinase Syk regulates the survival of chronic lymphocytic leukemia B cells through PKCdelta and proteasome-dependent regulation of Mcl-1 expression.

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

Erratum: A mammalian microRNA cluster controls DNA methylation and telomere recombination via Rbl2-dependent regulation of DNA methyltransferases

21 August 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3289956

Engraftment and growth of patient-derived retinoblastoma tumour in severe combined immunodeficiency mice

2 December 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22237022

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

1 reference

https://pubmed.ncbi.nlm.nih.gov/22237022

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE10733

1 reference

11 September 2017

1 reference

11 September 2017

PubMed publication ID

22237022

1 reference