Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity (Q41626666)

5 October 2017

Widespread siRNA "off-target" transcript silencing mediated by seed region sequence complementarity (English)

1 reference

5 October 2017

1

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author name string

Aimee L Jackson

1

1 reference

5 October 2017

Julja Burchard

2

1 reference

5 October 2017

Janell Schelter

3

1 reference

5 October 2017

B Nelson Chau

4

1 reference

5 October 2017

Michele Cleary

5

1 reference

5 October 2017

Lee Lim

6

1 reference

5 October 2017

Peter S Linsley

7

1 reference

5 October 2017

language of work or name

English

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publication date

8 May 2006

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5 October 2017

1 reference

5 October 2017

12

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5 October 2017

7

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5 October 2017

1179-1187

1 reference

Animal MicroRNAs confer robustness to gene expression and have a significant impact on 3'UTR evolution

5 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

The widespread impact of mammalian MicroRNAs on mRNA repression and evolution

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

Regulation by let-7 and lin-4 miRNAs results in target mRNA degradation

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

microRNA target predictions across seven Drosophila species and comparison to mammalian targets

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

siRNA-mediated off-target gene silencing triggered by a 7 nt complementation

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

Combinatorial microRNA target predictions

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammals

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

Principles of microRNA-target recognition

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

Microarray analysis shows that some microRNAs downregulate large numbers of target mRNAs

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

Kinetic analysis of the RNAi enzyme complex

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

MicroRNA-directed cleavage of HOXB8 mRNA

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

Specificity of microRNA target selection in translational repression

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

Short interfering RNAs can induce unexpected and divergent changes in the levels of untargeted proteins in mammalian cells

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

Prediction of mammalian microRNA targets

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

Identification of Drosophila MicroRNA targets

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

Expression profiling reveals off-target gene regulation by RNAi

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

Specificity of short interfering RNA determined through gene expression signatures

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

The microRNAs of Caenorhabditis elegans

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

Micro RNAs are complementary to 3' UTR sequence motifs that mediate negative post-transcriptional regulation

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

Expression profiling using microarrays fabricated by an ink-jet oligonucleotide synthesizer

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

Improved tools for biological sequence comparison

6 October 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1484447

RNA oligonucleotide synthesis via 5'-silyl-2'-orthoester chemistry

6 October 2017

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16682560

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1261/RNA.25706

1 reference

release_u6doc64cvbanbocuauaubabyeq

5 October 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/u6doc64cvbanbocuauaubabyeq

mapped directly with Wikidata item

24 November 2022

based on heuristic

1 reference

5 October 2017

PubMed publication ID

16682560

1 reference