PI-3-kinase is an essential anti-apoptotic effector in the proliferative response of primary human epithelial cells to mutant RAS (Q73816410)

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6 November 2019

title

PI-3-kinase is an essential anti-apoptotic effector in the proliferative response of primary human epithelial cells to mutant RAS (English)

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6 November 2019

1 reference

Gire V

1

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6 November 2019

Marshall C

series ordinal

2

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6 November 2019

Wynford-Thomas D

series ordinal

3

1 reference

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6 November 2019

language of work or name

English

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publication date

1 May 2000

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6 November 2019

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6 November 2019

volume

19

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6 November 2019

issue

19

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6 November 2019

page(s)

2269-2276

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PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo

6 November 2019

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Most human carcinomas of the exocrine pancreas contain mutant c-K-ras genes

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Protein kinase A-dependent and -independent signaling pathways contribute to cyclic AMP-stimulated proliferation.

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Concomitant activation of MEK-1 and Rac-1 increases the proliferative potential of thyroid epithelial cells, without affecting their differentiation.

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Activation of MAP kinase kinase is necessary and sufficient for PC12 differentiation and for transformation of NIH 3T3 cells

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Farnesyltransferase inhibitors and cancer treatment: targeting simply Ras?

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Akt phosphorylation of BAD couples survival signals to the cell-intrinsic death machinery

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Multiple mechanisms of interference between transformation and differentiation in thyroid cells

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The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

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Reinitiation of DNA synthesis and cell division in senescent human fibroblasts by microinjection of anti-p53 antibodies

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Activation of mitogen-activated protein kinase is necessary but not sufficient for proliferation of human thyroid epithelial cells induced by mutant Ras.

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Stimulation of membrane ruffling and MAP kinase activation by distinct effectors of RAS.

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Suppression of c-Myc-induced apoptosis by Ras signalling through PI(3)K and PKB.

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Oncogenic Ras activation of Raf/mitogen-activated protein kinase-independent pathways is sufficient to cause tumorigenic transformation

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Characterisation of human thyroid epithelial cells immortalised in vitro by simian virus 40 DNA transfection

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Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells

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Role of phosphoinositide 3-OH kinase in cell transformation and control of the actin cytoskeleton by Ras

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Activated MEK stimulates expression of AP-1 components independently of phosphatidylinositol 3-kinase (PI3-kinase) but requires a PI3-kinase signal To stimulate DNA synthesis

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Ras caught in another affair: the exchange factors for Ral.

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