Cellular and epigenetic drivers of stem cell ageing (Q88955687)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29858605%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

title

Cellular and epigenetic drivers of stem cell ageing (English)

1 reference

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29 March 2020

2

1 reference

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29 March 2020

Alessandro Ori

series ordinal

3

1 reference

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29 March 2020

4

K Lenhard Rudolph

1 reference

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29 March 2020

author name string

Maria Ermolaeva

series ordinal

1

1 reference

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29 March 2020

publication date

1 September 2018

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29858605%20AND%20SRC:MED&resulttype=core&format=json

Nature Reviews Molecular Cell Biology

29 March 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29858605%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

volume

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29858605%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

issue

9

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29858605%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

page(s)

594-610

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Ageing as developmental decay: insights from p16(INK4a.).

29 March 2020

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Enhancing Hematopoietic Stem Cell Transplantation Efficacy by Mitigating Oxygen Shock

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7 January 2021

The mitochondrial UPR: mechanisms, physiological functions and implications in ageing

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7 January 2021

Protein homeostasis and aging in neurodegeneration

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7 January 2021

Transcriptional and epigenetic regulation of autophagy in aging

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7 January 2021

Two Conserved Histone Demethylases Regulate Mitochondrial Stress-Induced Longevity

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7 January 2021

Stem cell aging. A mitochondrial UPR-mediated metabolic checkpoint regulates hematopoietic stem cell aging

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7 January 2021

Aged Stem Cells Reprogram Their Daily Rhythmic Functions to Adapt to Stress

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7 January 2021

What have we learned on aging from omics studies?

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7 January 2021

Nucleolar expansion and elevated protein translation in premature aging

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7 January 2021

Aging stem cells. A Werner syndrome stem cell model unveils heterochromatin alterations as a driver of human aging

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7 January 2021

Haematopoietic stem cells require a highly regulated protein synthesis rate

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7 January 2021

PERK Limits Drosophila Lifespan by Promoting Intestinal Stem Cell Proliferation in Response to ER Stress

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7 January 2021

Regulation of embryonic stem cell pluripotency by heat shock protein 90

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7 January 2021

Somatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan

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7 January 2021

Increased proteasome activity in human embryonic stem cells is regulated by PSMD11

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7 January 2021

The unfolded protein response governs integrity of the haematopoietic stem-cell pool during stress.

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7 January 2021

The asymmetric segregation of damaged proteins is stem cell-type dependent

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7 January 2021

Stem cells. Asymmetric apportioning of aged mitochondria between daughter cells is required for stemness

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7 January 2021

A mechanism for the segregation of age in mammalian neural stem cells

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7 January 2021

Accelerated aging and failure to segregate damaged proteins in Sir2 mutants can be suppressed by overproducing the protein aggregation-remodeling factor Hsp104p

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7 January 2021

p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice

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7 January 2021

Regulation of histone modifying enzymes by the ubiquitin-proteasome system

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7 January 2021

O-GlcNAcylation prevents aggregation of the Polycomb group repressor polyhomeotic

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7 January 2021

Histone chaperone networks shaping chromatin function

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7 January 2021

Histone exchange and histone modifications during transcription and aging

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7 January 2021

Elevated Histone Expression Promotes Life Span Extension

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7 January 2021

DNA damage checkpoints in stem cells, ageing and cancer.

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7 January 2021

Genome instability of ageing stem cells--Induction and defence mechanisms

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7 January 2021

Quiescent hematopoietic stem cells accumulate DNA damage during aging that is repaired upon entry into cell cycle

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7 January 2021

Replication stress is a potent driver of functional decline in ageing haematopoietic stem cells

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7 January 2021

Exit from dormancy provokes DNA-damage-induced attrition in haematopoietic stem cells.

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7 January 2021

Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age

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7 January 2021

DNA repair is limiting for haematopoietic stem cells during ageing

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7 January 2021

DNA double strand break repair, aging and the chromatin connection.

1 reference

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7 January 2021

Poly(ADP-ribose) polymerase-1-induced NAD(+) depletion promotes nuclear factor-κB transcriptional activity by preventing p65 de-acetylation.

1 reference

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7 January 2021

Glucose substitution prolongs maintenance of energy homeostasis and lifespan of telomere dysfunctional mice

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7 January 2021

Reduced histone biosynthesis and chromatin changes arising from a damage signal at telomeres

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7 January 2021

Chromatin modifications as determinants of muscle stem cell quiescence and chronological aging.

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7 January 2021

Rejuvenation of aged progenitor cells by exposure to a young systemic environment

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7 January 2021

The ageing systemic milieu negatively regulates neurogenesis and cognitive function.

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7 January 2021

Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells.

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7 January 2021

Restoring systemic GDF11 levels reverses age-related dysfunction in mouse skeletal muscle

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7 January 2021

Oxytocin is an age-specific circulating hormone that is necessary for muscle maintenance and regeneration

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7 January 2021

GDF11 Increases with Age and Inhibits Skeletal Muscle Regeneration

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7 January 2021

Human umbilical cord plasma proteins revitalize hippocampal function in aged mice

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7 January 2021

Hormonal control of stem cell systems

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7 January 2021

Oestrogen increases haematopoietic stem-cell self-renewal in females and during pregnancy

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7 January 2021

Sex hormones establish a reserve pool of adult muscle stem cells

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7 January 2021

A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

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7 January 2021

Rantes/Ccl5 influences hematopoietic stem cell subtypes and causes myeloid skewing

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7 January 2021

M-CSF instructs myeloid lineage fate in single haematopoietic stem cells

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7 January 2021

TNF/p38α/polycomb signaling to Pax7 locus in satellite cells links inflammation to the epigenetic control of muscle regeneration.

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7 January 2021

Dietary Restriction and AMPK Increase Lifespan via Mitochondrial Network and Peroxisome Remodeling.

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7 January 2021

Regulation of life span by the gut microbiota in the short-lived African turquoise killifish

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7 January 2021

Dietary restriction protects from age-associated DNA methylation and induces epigenetic reprogramming of lipid metabolism

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7 January 2021

Hematopoietic stem cell niche maintenance during homeostasis and regeneration

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7 January 2021

Defining the epithelial stem cell niche in skin

1 reference

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7 January 2021

The bone marrow niche for haematopoietic stem cells

1 reference

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7 January 2021

The central role of muscle stem cells in regenerative failure with aging

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7 January 2021

Adult intestinal stem cells: critical drivers of epithelial homeostasis and regeneration

1 reference

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7 January 2021

The Colonic Crypt Protects Stem Cells from Microbiota-Derived Metabolites

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

The aged niche disrupts muscle stem cell quiescence.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Canonical Wnt Signaling Ameliorates Aging of Intestinal Stem Cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Interleukin-22 promotes intestinal-stem-cell-mediated epithelial regeneration

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Aging, cellular senescence, and cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Cellular senescence in aging primates.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Telomere dysfunctional environment induces loss of quiescence and inherent impairments of hematopoietic stem cell function

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Osteopontin attenuates aging-associated phenotypes of hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Loss of fibronectin from the aged stem cell niche affects the regenerative capacity of skeletal muscle in mice

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7 January 2021

Targeting β1-integrin signaling enhances regeneration in aged and dystrophic muscle in mice

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7 January 2021

Decline in self-renewal factors contributes to aging of the stem cell niche in the Drosophila testis

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7 January 2021

Shedding light on the cell biology of extracellular vesicles

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7 January 2021

Myogenic Progenitor Cells Control Extracellular Matrix Production by Fibroblasts during Skeletal Muscle Hypertrophy

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https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

A CREB-Sirt1-Hes1 Circuitry Mediates Neural Stem Cell Response to Glucose Availability.

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https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Designer matrices for intestinal stem cell and organoid culture

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Aging of the skeletal muscle extracellular matrix drives a stem cell fibrogenic conversion.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Material Cues as Potent Regulators of Epigenetics and Stem Cell Function

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Intestinal label-retaining cells are secretory precursors expressing Lgr5.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Statistical control of peptide and protein error rates in large-scale targeted data-independent acquisition analyses

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7 January 2021

Dynamic Reorganization of Chromatin Accessibility Signatures during Dedifferentiation of Secretory Precursors into Lgr5+ Intestinal Stem Cells.

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7 January 2021

Induced Quiescence of Lgr5+ Stem Cells in Intestinal Organoids Enables Differentiation of Hormone-Producing Enteroendocrine Cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Non-equivalence of Wnt and R-spondin ligands during Lgr5+ intestinal stem-cell self-renewal

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Promoting health and longevity through diet: from model organisms to humans

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Dietary restriction improves repopulation but impairs lymphoid differentiation capacity of hematopoietic stem cells in early aging

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Dietary restriction enhances germline stem cell maintenance

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Short-term calorie restriction enhances skeletal muscle stem cell function

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

A Periodic Diet that Mimics Fasting Promotes Multi-System Regeneration, Enhanced Cognitive Performance, and Healthspan.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Sex difference in pathology of the ageing gut mediates the greater response of female lifespan to dietary restriction.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Lifespan-extending caloric restriction or mTOR inhibition impair adaptive immunity of old mice by distinct mechanisms

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Lifelong dietary intervention does not affect hematopoietic stem cell function.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

mTORC1 and SIRT1 Cooperate to Foster Expansion of Gut Adult Stem Cells during Calorie Restriction.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Structural modulation of gut microbiota in life-long calorie-restricted mice

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Using DNA Methylation Profiling to Evaluate Biological Age and Longevity Interventions.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Paternal diet defines offspring chromatin state and intergenerational obesity

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Vitamin A-Retinoic Acid Signaling Regulates Hematopoietic Stem Cell Dormancy.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Restoration of TET2 Function Blocks Aberrant Self-Renewal and Leukemia Progression.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Ascorbate regulates haematopoietic stem cell function and leukaemogenesis.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

1 reference

7 January 2021

Aging effects on DNA methylation modules in human brain and blood tissue

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

DNA methylation age of human tissues and cell types

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Multi-tissue DNA methylation age predictor in mouse

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Aging of blood can be tracked by DNA methylation changes at just three CpG sites

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

An integrative multi-scale analysis of the dynamic DNA methylation landscape in aging

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Proliferation-dependent alterations of the DNA methylation landscape underlie hematopoietic stem cell aging

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Total synthesis of 6-deoxypladienolide D and Assessment of Splicing Inhibitory Activity in a Mutant SF3B1 cancer cell line

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

H3K4me1 marks DNA regions hypomethylated during aging in human stem and differentiated cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Diverse interventions that extend mouse lifespan suppress shared age-associated epigenetic changes at critical gene regulatory regions

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Caloric restriction delays age-related methylation drift

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Epigenetic stress responses induce muscle stem-cell ageing by Hoxa9 developmental signals

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Epigenomic profiling of young and aged HSCs reveals concerted changes during aging that reinforce self-renewal

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Epigenetic Control of Stem Cell Potential during Homeostasis, Aging, and Disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Dynamic changes in chromatin states during specification and differentiation of adult intestinal stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Methylation reveals a niche: stem cell succession in human colon crypts

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Methylation patterns and mathematical models reveal dynamics of stem cell turnover in the human colon

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

DNA methylation dynamics during intestinal stem cell differentiation reveals enhancers driving gene expression in the villus

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

DNA methylation is required for the control of stem cell differentiation in the small intestine

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Small bowel enterocyte apoptosis and proliferation are increased in the elderly

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Proliferating cell nuclear antigen expression is increased in small bowel epithelium in the elderly

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Methylation of polycomb target genes in intestinal cancer is mediated by inflammation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

The Janus face of DNA methylation in aging

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Epigenetic control of the host gene by commensal bacteria in large intestinal epithelial cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Proliferation Drives Aging-Related Functional Decline in a Subpopulation of the Hematopoietic Stem Cell Compartment

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Single-Cell Analysis of Human Pancreas Reveals Transcriptional Signatures of Aging and Somatic Mutation Patterns

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Single-Cell Chromatin Modification Profiling Reveals Increased Epigenetic Variations with Aging.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Differentiation imbalance in single oesophageal progenitor cells causes clonal immortalization and field change.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Clonal hematopoiesis and blood-cancer risk inferred from blood DNA sequence

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Paternal age effect mutations and selfish spermatogonial selection: causes and consequences for human disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Mitochondrial DNA mutations are established in human colonic stem cells, and mutated clones expand by crypt fission.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Large chromosome deletions, duplications, and gene conversion events accumulate with age in normal human colon crypts

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Leukemia-associated somatic mutations drive distinct patterns of age-related clonal hemopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Identification of Aging-Associated Gene Expression Signatures That Precede Intestinal Tumorigenesis.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Identification of pre-leukaemic haematopoietic stem cells in acute leukaemia

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Recurrent somatic TET2 mutations in normal elderly individuals with clonal hematopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Epigenetic Perturbations by Arg882-Mutated DNMT3A Potentiate Aberrant Stem Cell Gene-Expression Program and Acute Leukemia Development

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

DNMT3A(R882H) mutant and Tet2 inactivation cooperate in the deregulation of DNA methylation control to induce lymphoid malignancies in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

TET2 mutations and their clinical correlates in polycythemia vera, essential thrombocythemia and myelofibrosis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

DNMT3A Loss Drives Enhancer Hypomethylation in FLT3-ITD-Associated Leukemias.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Dnmt3a is essential for hematopoietic stem cell differentiation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Ten-Eleven-Translocation 2 (TET2) negatively regulates homeostasis and differentiation of hematopoietic stem cells in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

DNMT3A and TET2 compete and cooperate to repress lineage-specific transcription factors in hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Clonal hematopoiesis associated with TET2 deficiency accelerates atherosclerosis development in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Clonal Hematopoiesis and Risk of Atherosclerotic Cardiovascular Disease.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Increased cell-to-cell variation in gene expression in ageing mouse heart

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Tumor evolution. High burden and pervasive positive selection of somatic mutations in normal human skin

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Intestinal crypt homeostasis results from neutral competition between symmetrically dividing Lgr5 stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Leukemic IDH1 and IDH2 mutations result in a hypermethylation phenotype, disrupt TET2 function, and impair hematopoietic differentiation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Janus kinase 2: an epigenetic 'writer' that activates leukemogenic genes.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Spliceosome mutations exhibit specific associations with epigenetic modifiers and proto-oncogenes mutated in myelodysplastic syndrome

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

p53 induces distinct epigenetic states at its direct target promoters

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Non-canonical functions of the DNA methylome in gene regulation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Genomes of replicatively senescent cells undergo global epigenetic changes leading to gene silencing and activation of transposable elements

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

SIRT6 represses LINE1 retrotransposons by ribosylating KAP1 but this repression fails with stress and age.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Intragenic DNA methylation prevents spurious transcription initiation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Blocking promiscuous activation at cryptic promoters directs cell type-specific gene expression

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

CTCF-promoted RNA polymerase II pausing links DNA methylation to splicing

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

HP1 is involved in regulating the global impact of DNA methylation on alternative splicing

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Alternative splicing: decoding an expansive regulatory layer

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Translating the Histone Code

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Notch signaling: cell fate control and signal integration in development

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

The Wnt signaling pathway in development and disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Wnt/beta-catenin signaling in development and disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Functions and regulations of fibroblast growth factor signaling during embryonic development

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

The TGF-beta superfamily: new members, new receptors, and new genetic tests of function in different organisms

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

The p38 MAPK signaling pathway: a major regulator of skeletal muscle development

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Programmed cell senescence during mammalian embryonic development

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Senescence is a developmental mechanism that contributes to embryonic growth and patterning

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Rho GTPase Cdc42 coordinates hematopoietic stem cell quiescence and niche interaction in the bone marrow

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Cdc42 activity regulates hematopoietic stem cell aging and rejuvenation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Discrete roles of canonical and non-canonical Wnt signaling in hematopoiesis and lymphopoiesis

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

A canonical to non-canonical Wnt signalling switch in haematopoietic stem-cell ageing.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Wnt5a regulates hematopoietic stem cell proliferation and repopulation through the Ryk receptor

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Wnt5a inhibits canonical Wnt signaling in hematopoietic stem cells and enhances repopulation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Noncanonical Wnt signaling maintains hematopoietic stem cells in the niche

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Wnt activity and basal niche position sensitize intestinal stem and progenitor cells to DNA damage.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Lamin A-dependent misregulation of adult stem cells associated with accelerated ageing

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Nuclear envelope defects cause stem cell dysfunction in premature-aging mice

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

A systems biology approach to Down syndrome: identification of Notch/Wnt dysregulation in a model of stem cells aging.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Telomerase abrogates aneuploidy-induced telomere replication stress, senescence and cell depletion.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Notch-mediated restoration of regenerative potential to aged muscle

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Geriatric muscle stem cells switch reversible quiescence into senescence.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Stem-cell ageing modified by the cyclin-dependent kinase inhibitor p16INK4a

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

A Notch positive feedback in the intestinal stem cell niche is essential for stem cell self-renewal.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Frequent Somatic Mutation in Adult Intestinal Stem Cells Drives Neoplasia and Genetic Mosaicism during Aging

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Notch/gamma-secretase inhibition turns proliferative cells in intestinal crypts and adenomas into goblet cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Rejuvenation of the muscle stem cell population restores strength to injured aged muscles

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

In vitro generation of long-term repopulating hematopoietic stem cells by fibroblast growth factor-1

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Fibroblast growth factor-7 partially reverses murine thymocyte progenitor aging by repression of Ink4a

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Fibroblast growth factor 10 alters the balance between goblet and Paneth cells in the adult mouse small intestine.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Directed differentiation of human pluripotent stem cells into intestinal tissue in vitro

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Fibroblast growth factor receptor-3 regulates Paneth cell lineage allocation and accrual of epithelial stem cells during murine intestinal development

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Fibroblast growth factor receptor 2c signaling is required for intestinal cell differentiation in zebrafish

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

The role of p38b MAPK in age-related modulation of intestinal stem cell proliferation and differentiation in Drosophila

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Epigenetic control of adult stem cell function

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

In Vivo Amelioration of Age-Associated Hallmarks by Partial Reprogramming

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Satellite cells and the muscle stem cell niche

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Mesenchymal stem cells/multipotent stromal cells (MSCs) are glycolytic and thus glucose is a limiting factor of in vitro models of MSC starvation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

UCP2 regulates energy metabolism and differentiation potential of human pluripotent stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Regulation of the HIF-1alpha level is essential for hematopoietic stem cells

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

An MTCH2 pathway repressing mitochondria metabolism regulates haematopoietic stem cell fate

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

A subpopulation of adult skeletal muscle stem cells retains all template DNA strands after cell division

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Glycolysis-mediated changes in acetyl-CoA and histone acetylation control the early differentiation of embryonic stem cells.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

NAD+ and sirtuins in aging and disease

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Cdkn1a deletion improves stem cell function and lifespan of mice with dysfunctional telomeres without accelerating cancer formation

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Naturally occurring p16(Ink4a)-positive cells shorten healthy lifespan

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Clearance of senescent cells by ABT263 rejuvenates aged hematopoietic stem cells in mice

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Cellular Aging Contributes to Failure of Cold-Induced Beige Adipocyte Formation in Old Mice and Humans

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Telomere dysfunction induces environmental alterations limiting hematopoietic stem cell function and engraftment

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Feedback between p21 and reactive oxygen production is necessary for cell senescence

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Tissue damage and senescence provide critical signals for cellular reprogramming in vivo.

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

An essential role for senescent cells in optimal wound healing through secretion of PDGF-AA

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Cancer genetics and epigenetics: two sides of the same coin?

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

MLL translocations, histone modifications and leukaemia stem-cell development

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

DNMT3A in haematological malignancies

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Metabolic consequences of oncogenic IDH mutations

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Epigenetic changes of DNA repair genes in cancer

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

CpG island methylator phenotype (CIMP) of colorectal cancer is best characterised by quantitative DNA methylation analysis and prospective cohort studies

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Nascent chromatin capture proteomics determines chromatin dynamics during DNA replication and identifies unknown fork components

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Human mutation rate associated with DNA replication timing

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

Tissue-specific mutation accumulation in human adult stem cells during life

1 reference

https://api.crossref.org/works/10.1038%2FS41580-018-0020-3

7 January 2021

10.1038/S41580-018-0020-3

Identifiers

DOI

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:29858605%20AND%20SRC:MED&resulttype=core&format=json

29 March 2020

1 reference