OR8D2

OR8D2
Identifiers
Aliases	OR8D2, JCG2, olfactory receptor family 8 subfamily D member 2 (gene/pseudogene), olfactory receptor family 8 subfamily D member 2
External IDs	MGI: 3030758; HomoloGene: 128215; GeneCards: OR8D2; OMA:OR8D2 - orthologs
Gene location (Human) Chr. Chromosome 11 (human) Band 11q24.2 Start 124,319,262 bp End 124,320,197 bp
Gene location (Mouse) Chr. Chromosome 9 (mouse) Band 9|9 A5.1 Start 38,755,745 bp End 38,762,791 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in testicle n/a More reference expression data BioGPS More reference expression data
Gene ontology Molecular function G protein-coupled receptor activity odorant binding signal transducer activity olfactory receptor activity Cellular component integral component of membrane membrane plasma membrane Biological process sensory perception of smell signal transduction response to stimulus detection of chemical stimulus involved in sensory perception of smell G protein-coupled receptor signaling pathway Sources:Amigo / QuickGO
Orthologs Species Human Mouse Entrez 283160 404322 Ensembl ENSG00000279116 ENSMUSG00000062103 UniProt Q9GZM6 Q7TRB8 RefSeq (mRNA) NM_001002918 NM_207560 RefSeq (protein) NP_001002918 NP_997443 Location (UCSC) Chr 11: 124.32 – 124.32 Mb Chr 9: 38.76 – 38.76 Mb PubMed search
Wikidata
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Olfactory receptor 8D2 is a protein that in humans is encoded by the OR8D2 gene.

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.

See also

• Olfactory receptor

Further reading

• Gaudin JC, Breuils L, Haertlé T (2002). "New GPCRs from a human lingual cDNA library". Chem. Senses. 26 (9): 1157–66. doi:10.1093/chemse/26.9.1157. PMID 11705801.
• Malnic B, Godfrey PA, Buck LB (2004). "The human olfactory receptor gene family". Proc. Natl. Acad. Sci. U.S.A. 101 (8): 2584–9. Bibcode:2004PNAS..101.2584M. doi:10.1073/pnas.0307882100. PMC 356993. PMID 14983052.

External links

• OR8D2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.