2,3-二甲基-1-丁醇

2,3-二甲基-1-丁醇
英文名	2,3-Dimethyl-1-butanol
识别
CAS号	19550-30-2
性质
化学式	C6H14O
摩尔质量	102.17 g·mol−1
密度	0.905 g·cm−3（20 °C）; 0.8237 g·cm−3（25 °C）
熔点	42—43.5 °C（315.1—316.6 K）
沸点	145 °C（418 K）
	若非注明，所有数据均出自标准状态（25 ℃，100 kPa）下。

2,3-二甲基-2-丁醇是一种有机化合物，化学式为C₆H₁₄O是六碳醇的同分异构体之一。它可由2,3-二甲基丁酸（或2,3-二甲基丁醛^[5]）在乙醚中被氢化铝锂还原^[6]，或者通过2,3-二甲基-1-丁烯的硼氢化-氧化反应制得。^[7]它和甲磺酰氯反应，得到1-甲磺酸-2,3-二甲基-1-丁酯。^[8]

参考文献

^ G. E. McCASLAND, Stephen Proskow. Synthesis of 3,4-Dimethyl Spirobipyrrolidinium Salts by Cyclization of Pyrrolidinealkanols. The Journal of Organic Chemistry. 1957-02, 22 (2): 122–126 [2019-11-08]. ISSN 0022-3263. doi:10.1021/jo01353a004 （英语）.
^ Tsuda, K.; Hayazu, R.; Kishida, Y. Absolute configuration of 24-ethyl of stigmasterol. Chemistry & Industry (London, United Kingdom), 1959. pp 1411-1412. ISSN: 0009-3068.
^ Mahesh J. Sanganee, Patrick G. Steel, Daniel K. Whelligan. Stereochemistry of the reaction of Si–phenyl silenes with butadienes: elaboration of the silacycloadducts to provide a novel route to substituted lactones. Org. Biomol. Chem. 2004, 2 (16): 2393–2402 [2019-11-08]. ISSN 1477-0520. doi:10.1039/B404175E （英语）.
^ Nienburg, Hans; Friedrichsen, Wilhelm. Primary alcohols. 1952. DE 844891
^ Taeil Shin, Hyungsoo Kim, Sungmin Kim, Ansoo Lee, Min-Seob Seo, Jonghoon Choi, Hyungjun Kim, Hyunwoo Kim. Ligand-Controlled Direct Hydroformylation of Trisubstituted Olefins. Organic Letters. 2019-08-02, 21 (15): 5789–5792 [2019-11-08]. ISSN 1523-7060. doi:10.1021/acs.orglett.9b01639 （英语）.
^ Michael RowleySome uses of tin compounds in organic synthesis. Sel. Org. React. Database (SORD) 1986, (20121004). (Dissertation)
^ N.M. O'Connell, Y.C. O'Callaghan, N.M. O'Brien, A.R. Maguire, F.O. McCarthy. Synthetic routes to campesterol and dihydrobrassicasterol: a first reported synthesis of the key phytosterol dihydrobrassicasterol. Tetrahedron. 2012-06, 68 (25): 4995–5004 [2019-11-08]. doi:10.1016/j.tet.2012.04.060 （英语）.
^ Mingyu Yang, Bo Su, Yang Wang, Kang Chen, Xingyu Jiang, Yun-Fei Zhang, Xi-Sha Zhang, Guihua Chen, Ye Cheng, Zhichao Cao, Qing-Yun Guo, Lushun Wang, Zhang-Jie Shi. Silver-catalysed direct amination of unactivated C–H bonds of functionalized molecules. Nature Communications. 2014-12, 5 (1) [2019-11-08]. ISSN 2041-1723. doi:10.1038/ncomms5707. （原始内容存档于2020-05-19）（英语）.

[1] G. E. McCASLAND, Stephen Proskow. Synthesis of 3,4-Dimethyl Spirobipyrrolidinium Salts by Cyclization of Pyrrolidinealkanols. The Journal of Organic Chemistry. 1957-02, 22 (2): 122–126 [2019-11-08]. ISSN 0022-3263. doi:10.1021/jo01353a004 （英语）.

[2] Tsuda, K.; Hayazu, R.; Kishida, Y. Absolute configuration of 24-ethyl of stigmasterol. Chemistry & Industry (London, United Kingdom), 1959. pp 1411-1412. ISSN: 0009-3068.

[3] Mahesh J. Sanganee, Patrick G. Steel, Daniel K. Whelligan. Stereochemistry of the reaction of Si–phenyl silenes with butadienes: elaboration of the silacycloadducts to provide a novel route to substituted lactones. Org. Biomol. Chem. 2004, 2 (16): 2393–2402 [2019-11-08]. ISSN 1477-0520. doi:10.1039/B404175E （英语）.

[4] Nienburg, Hans; Friedrichsen, Wilhelm. Primary alcohols. 1952. DE 844891

[5] Taeil Shin, Hyungsoo Kim, Sungmin Kim, Ansoo Lee, Min-Seob Seo, Jonghoon Choi, Hyungjun Kim, Hyunwoo Kim. Ligand-Controlled Direct Hydroformylation of Trisubstituted Olefins. Organic Letters. 2019-08-02, 21 (15): 5789–5792 [2019-11-08]. ISSN 1523-7060. doi:10.1021/acs.orglett.9b01639 （英语）.

[6] Michael RowleySome uses of tin compounds in organic synthesis. Sel. Org. React. Database (SORD) 1986, (20121004). (Dissertation)

[7] N.M. O'Connell, Y.C. O'Callaghan, N.M. O'Brien, A.R. Maguire, F.O. McCarthy. Synthetic routes to campesterol and dihydrobrassicasterol: a first reported synthesis of the key phytosterol dihydrobrassicasterol. Tetrahedron. 2012-06, 68 (25): 4995–5004 [2019-11-08]. doi:10.1016/j.tet.2012.04.060 （英语）.

[8] Mingyu Yang, Bo Su, Yang Wang, Kang Chen, Xingyu Jiang, Yun-Fei Zhang, Xi-Sha Zhang, Guihua Chen, Ye Cheng, Zhichao Cao, Qing-Yun Guo, Lushun Wang, Zhang-Jie Shi. Silver-catalysed direct amination of unactivated C–H bonds of functionalized molecules. Nature Communications. 2014-12, 5 (1) [2019-11-08]. ISSN 2041-1723. doi:10.1038/ncomms5707. （原始内容存档于2020-05-19）（英语）.

[1]

[2]

[3]

[4]

[5]

[6]

[7]

[8]