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filingDate 1996-03-27^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 1998-01-14^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-0817835-A1
titleOfInvention Production of antibodies using cre-mediated site-specific recombination
abstract A method to produce a cell expressing an antibody from a genomic sequence of a cell which has a modified immunoglobulin locus is disclosed. The method takes advantage of Cre-mediated site-specific recombination and homologous recombination. The method involves first introducing a lox site into an immunoglobulin locus and then using the lox site as a target for introduction of gene modifications via Cre-mediated in vivo recombination.
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http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8A4C3
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA5F5U6
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID226395835
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8A363
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA2BLC6
http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID136313084
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA1RV79
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8A3I5
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB6YUU0
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ59800
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO59841
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ6LL68
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB7UJI9
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ6GGY1
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8A341
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ60034
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP00634
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ5JHB5
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8A6V8
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID20054941
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID11809
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP46713
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ60HF6
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA0A0H3MAB5
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA1A831
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ58D55
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP81650
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ9V1P1
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB2VHN8
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCO60109
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8ZWK7
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC4KHW5
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCC7ASJ5
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8A934
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ7MG04
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP69154
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID11886
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8A9Q8
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP16858
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA7ZM66
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID188583
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ8A921
http://rdf.ncbi.nlm.nih.gov/pubchem/anatomy/ANATOMYID2405
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCB4S2K9
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ0T4H1
http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID126941
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID6343933
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP00722
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP0CE13
http://rdf.ncbi.nlm.nih.gov/pubchem/gene/GID102723407
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCP46795
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCQ32G72
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA3FEW8
http://rdf.ncbi.nlm.nih.gov/pubchem/protein/ACCA4YHA5

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