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filingDate 2016-11-30^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2020-10-27^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48c0675f6dae4357440cb10ba38034f7
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publicationDate 2020-10-27^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-10813346-B2
titleOfInvention Enhanced immunoglobulin diversity
abstract The invention provides compositions and methods for enhanced production of immunoglobulin diversity. Specifically, the invention provides compositions and methods for making accessible a B cell receptor repertoire that has not been culled by developmental tolerance mechanisms. The invention also provides transgenic animals, cells, and antibodies resulting from these compositions and methods.
priorityDate 2015-12-03^^<http://www.w3.org/2001/XMLSchema#date>
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