| abstract |
The invention relates to cyclized derivatives of N dimethyl biguanide (imidodicarbonimidiodiamine) and the applications of these substances as medicaments. Chemical compounds derived from dimethyl biguanide corresponding to the following general formula (I): (CF DRAWING IN BOPI) in which the group -CO-R-CO- is derived from a dicarboxylic acid anhydride (or diacid) and more in particular in which R represents a hydrocarbon chain of 4 to 6 carbon atoms saturated or not, optionally substituted and in particular with methyl, propyl or allyl groups; an aromatic ring, in particular benzene, naphthalene, where appropriate substituted by halogen atoms, hydroxyls or alliphatic chains; a ring or non-aromatic of 5 to 6 carbon atoms, in particular a cyclohexane or cyclopentane group optionally substituted with hydroxyl groups or alliphatic chains; an aromatic or non-aromatic ring of 5 to 6 atoms comprising a heteroatom such as nitrogen or oxygen. |