http://rdf.ncbi.nlm.nih.gov/pubchem/patent/KR-101510742-B1

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filingDate 2013-05-13^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2015-04-10^^<http://www.w3.org/2001/XMLSchema#date>
publicationDate 2015-04-10^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber KR-101510742-B1
titleOfInvention Peptides for Inducing Mast Cell-Spepcific Apoptosis and Uses Thereof
abstract The present invention relates to peptides which have the same or similar function as the function of natural semaphorin 3A, but also have excellent skin permeability according to their small size and their uses. The peptide of the present invention not only induces mast cell-specific apoptosis but also inhibits mast cell activity (for example, decreases secretion amount of histamine and inhibits beta-hexosaminidase activity) do. In addition, the peptides of the present invention inhibit FcεRI signaling, more specifically complex formation of the FcεRI receptor, which results in the phosphorylation inhibition of ERK1 / 2, p38 or Lyn. Therefore, the excellent activity and stability of the peptide of the present invention can be very usefully applied to medicines, quasi-drugs, and cosmetics.
priorityDate 2013-05-13^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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