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filingDate 2019-05-29^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2021-08-17^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-11091793-B2
titleOfInvention Detection of hydroxymethylcytosine bases
abstract Methodologies for labeling the epigenetic modification 5-hydroxymethylcytosine (5hmC) along a DNA molecule, and for determining a presence or a level of this epigenetic modification based on a ratio of fluorescence intensity of a labeled DNA sample to absorption intensity of the DNA sample at 260 nm are disclosed. Related compositions and reagents, and methods of preparing same are also disclosed.
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