http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11364249-B2

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filingDate 2020-04-08^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-06-21^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3e556d1981ad03e234b6c6925000fed8
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publicationDate 2022-06-21^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-11364249-B2
titleOfInvention High-strength testosterone undecanoate compositions
abstract The present disclosure is drawn to pharmaceutical compositions and oral dosage capsules containing testosterone undecanoate, as well as related methods. The capsule includes a capsule shell and a capsule fill. The capsule fill can include a solubilizer and about 14 wt % to about 35 wt % testosterone undecanoate based on the total capsule fill. The oral dosage capsule is such that when a single oral administration to a male subject of one or more capsules with a total testosterone undecanoate daily dose of about 350 mg to about 650 mg it provides a ratio of serum testosterone Cmax to serum testosterone Cave of about 2.7 or less. In yet another embodiment, a method for providing a serum concentration of testosterone within a target serum testosterone concentration Cave range for a male subject is provided.
priorityDate 2010-11-30^^<http://www.w3.org/2001/XMLSchema#date>
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