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filingDate 1994-11-23^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 1996-08-06^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0ee804e511f4dc0cc9b1f988e07be06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1e1df0905f78a788cfeb3e830d40649
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publicationDate 1996-08-06^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-5543393-A
titleOfInvention Cyclosporin containing powder composition
abstract The present invention relates to a cyclosporin-containing powder composition which comprises cyclosporin, a non-ionic hydrophilic surfactant and a porous carrier. In addition, the present invention relates to a method for preparing the cyclosporin-containing powder composition which comprises dissolving cyclosporin and a non-ionic hydrophilic surfactant in an organic solvent, adding a porous carrier to the resulting solution and then evaporating the organic solvent from the mixture. The powder composition of the present invention is stable and does not require a special manufacturing technique when it is formulated. In addition, since the powder composition of the present invention does not contain an organic solvent, the necessity of a special package is excluded. Furthermore, the composition of the present invention provides an improved bioavailability which results in decrease of a single dosage, and therefore, can contribute to the alleviation of the side effects associated with cyclosporin.
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