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filingDate 2019-04-19^^<http://www.w3.org/2001/XMLSchema#date>
grantDate 2022-09-27^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2022-09-27^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-11452733-B2
titleOfInvention Compounds and their uses for alleviating menopause-associated symptoms
abstract The present invention relates to a hormone replacement therapy, to the associated compounds and to the associated packaging units, for alleviating menopause-associated symptoms which is based on the administration to a female mammal of an estetrol component at specified daily doses, optionally in combination with a progestogenic component. The therapy enjoys a statistically significant efficacy combined with a favourable profile for side effects compared to currently available methods for alleviating menopause-associated symptoms.
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