abstract |
NOVEL COMPOUNDS HAVING THE FORMULA 4-(((R)N-PHENYL)-CO-)PIPERIDINE WHEREIN N IS A POSITIVE WHOLE INTEGER OF FROM 1 TO 3; R REPRESENTS PHENYL, A STRAIGHT OR BRANCHED ALKYL CHAIN OF FROM 1 TO 4 CARBON ATOMS ATTACHED TO THE PHENYL RING AT THE ORTHO, META, OR PARA POSITIONS, OR A DIFUNCTIONAL 1,4-BUTADIENYLENE MOIETY WHICH TOGETHER WITH THE PHENYL RING FORMS A NAPHTHYL RING WITH THE PROVISO THAT WHEN R REPRESENTS A DIFUNCTIONAL 1,4-BUTADIENYLENE MOIETY, N IS EQUAL TO 1; OR PHARMACEUTICALLY ACCEPTABLE ACID SALTS THEREOF, ARE USEFUL AS ANALGESIC AND AS ANTICOAGULANT AGENTS. |