http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4348322-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73ee0bacab5a7576a6a3244747f6ea99 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C45-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C59-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D317-34 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C45-49 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C59-66 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D317-34 |
| filingDate | 1981-03-11^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1982-09-07^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c75cb18c21438c09db36f4ef6863a96 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_23a1b54184a327b8d647182aedf24c78 |
| publicationDate | 1982-09-07^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4348322-A |
| titleOfInvention | Dioxolane derivatives |
| abstract | The invention is concerned with novel dioxolane derivatives of the formula: ##STR1## in which R a is hydrogen or (1-4C)alkyl and R b is (1-4C)alkyl or phenyl optionally bearing a halogeno substituent; their production; and their use for the manufacture of certain known anti-arthritic acids of the formula: ##STR2## and, in particular, those acids in which R a =R b =methyl or R a =ethyl and R b =phenyl, by a novel reduction process. The preferred reduction procedures involve the use of an alkali metal borohydride or cyanoborohydride in the presence of a noble metal catalyst, or the use of an α-branched alkyl or cycloalkyl Grignard agent. n The use of the derivatives of formula I avoids the need for potentially toxic reagents and reactive intermediates in the previously known processes for the production of the acids of formula V. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9256125-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5424136-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2014295347-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003018077-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5874612-A |
| priorityDate | 1980-04-03^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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