http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-4845233-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e05bb68c8cabe6d8f63fc6b767b82abc |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D233-70 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D233-70 |
| filingDate | 1987-09-11^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate | 1989-07-04^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1cd0e6bcd075346899cb7ba0fff9058f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_df4c6385e48bf69ce49155ee628f8c54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b5514eacc868d2ac4308d173ece7462a |
| publicationDate | 1989-07-04^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | US-4845233-A |
| titleOfInvention | Imidazolin-2-ones |
| abstract | A compound having the formula: <IMAGE> wherein R, R1 and R2 are independently selected from hydrogen; hydroxy; fluorine; bromine; chlorine; C1-C20 alkyl; C2-C20 alkenyl; C2-C20 alkynyl; C3-C10 cycloalkyl; C2-C20 (monohydroxy or polyhydroxy)alkyl; C1-C20 (monohalo or polyhalo)alkyl; carboxy; C1-C20 alkylcarboxy; C1-C20 alkenylcarboxy; C1-C20 carboxyalkyl; C1-C20 alkanoyl; C1-C20 alkanoyloxy; C1-C20 alkoxycarbonyl; carbamoyl; carbamyl; C1-C20 alkylcarbamyl; sulfo; C1-C20 alkylsulfonyl; C1-C20 alkylsulfinyl; C1-C20 alkylsulfoxide; C1-C20 alkylsulfone; thio; C1-C20 alkylthio; amino; nitro; C1-C20 alkylamino; C1-C20 aminoalkyl; substituted or unsubstituted phenyl or benzyl, the substituents being selected from hydroxy, fluorine, bromine, chlorine, C1-C20 alkyl, C2-C20 alkenyl, C2-C20 (monohydroxy or polyhydroxy)alkyl, X is methyl or oxygen and n is 0 to 20. The invention is also directed to a method for increasing the topical penetration of a physiologically active agent across the skin or membrane of a mammalian organism. Also claimed is a pharmaceutical composition and a novel method for preparing 1-substituted-4-imidazolin-2-one. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7612033-B2 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004176473-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5383848-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6166220-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5334138-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6008371-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5869515-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5498723-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5744613-A |
| priorityDate | 1987-09-11^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
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