| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2f707cf486730a9439aa4989ef762f56 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S424-812 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-127
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K9-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-39 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-127 |
| filingDate |
1988-07-08^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1990-08-21^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e8323e67ae8ed34bcd22bf59be487080
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4fef207e163fe5125d02466a6dcdf4d7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_707adc41981653ca598bfa5c6c492522 |
| publicationDate |
1990-08-21^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-4950645-A |
| titleOfInvention |
Composition for macrophage activation |
| abstract |
The present invention provides a novel lipophilic dissacharide-tripeptide derivative of the known base compound muramyl dipeptide (MDP). The compound of the invention is preferably encapsulated into multilamellar liposomes, which can be formed from phosphatidyl choline and phosphatidyl glycerol. The compound is effective in activating human monocytes with subsequent destruction of tumor cells. The compound is also nontoxic in dosages well exceeding anticipated human dosages. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-9014837-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009191226-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009117149-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003147898-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11376324-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6566500-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6218166-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8017754-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7829668-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5158941-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5416070-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6008333-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004009148-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5750665-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2021178637-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2007014795-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1975231-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-6299884-B1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020049169-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-5089470-A |
| priorityDate |
1988-07-08^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |