| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_999ffa129c0939d017374607587e4eb3 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y10S435-948
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2740-16322
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-005 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-16
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-34 |
| filingDate |
1993-11-04^^<http://www.w3.org/2001/XMLSchema#date> |
| grantDate |
1996-09-10^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5d98de1289d912806a936501676db2dd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8eafec1dd40d55706d5c143391ecb9e5
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ed9c9f53e3ec2a836b7cc2800ee1c1b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8938851e2118d8df79902500a2079da7 |
| publicationDate |
1996-09-10^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
US-5554528-A |
| titleOfInvention |
Compositions and methods for inhibition of HIV production |
| abstract |
All lines of mammalian origin which have been stably transformed with a chimeric toxin gene expressed under the regulatory control of HIV cis-acting sequences and HIV trans-acting factors are provided by the present invention. HIV infection of a cell of such a transformed cell line results in the death of that cell due to the specific induction of toxin gene expression within the cell. As specifically exemplified, the toxin gene is the diphtheria toxin fragment A gene or a tox176 fragment A chain gene. Also provided by the present invention are recombinant nucleic acid molecules suitable for the stable transformation of a mammalian cell line to produce a transformed cell which will effectively commit suicide in response to HIV infection due to induction of toxin gene expression. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2004043949-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3072901-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004045548-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2308987-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2007020873-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010113566-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-1270732-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2679596-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3187585-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2010135716-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7455841-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009170800-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2010137415-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8841438-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8202847-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2568289-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2003143743-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03000907-A3
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2011050395-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-03000907-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2308987-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2004045548-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2011002956-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-100379853-C
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3069730-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2012170765-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2006140978-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9719085-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/JP-2004536598-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2873423-A2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9822380-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8685407-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-7547551-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2008133137-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8889844-B2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-2848937-A1 |
| priorityDate |
1987-08-21^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |