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filingDate 2001-06-20^^<http://www.w3.org/2001/XMLSchema#date>
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inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ac6c8bef817d7b969d02ef775e6334ba
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publicationDate 2002-10-15^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-6465680-B2
titleOfInvention Process for preparing malonate derivatives or β-keto esters from epoxide derivatives
abstract A process for preparing a malonic acid monoester or beta-ketoester from an epoxide includes the steps of reacting an epoxide with carbon monoxide and an alcohol in the presence of a catalytic amount of a cobalt compound and at least one promoter to produce a beta-hydroxyester, separating the beta-hydroxyester from the cobalt compound and the promoter, and oxidizing the beta-hydroxyester to produce a malonic acid monoester or beta-ketoester.
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