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filingDate 1999-09-03^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2009-04-14^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber US-7517527-B2
titleOfInvention Immunotoxin with in vivo T cell suppressant activity and methods of use
abstract Provided is a method of treating an autoimmune disease in an animal comprising administering to the animal an antibody-DT mutant immunotoxin which routes by the anti-CD3 pathway, or derivatives thereof, under conditions such that the autoimmune disease is treated. In a further embodiment, the invention provides a method of treating T cell leukemias or lymphomas in an animal comprising administering to the animal an antibody-DT mutant immunotoxin which routes by the anti-CD3 pathway, or derivatives thereof, under conditions such that the T cell leukemias or lymphomas are treated.
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