Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1920e91404b2210e92a6d163c1da93a4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e88a4430d98d16c6a761aa63cfb3c85d http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f1f1946cd9c3ea704f2629363018ed58 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b730a416afe49ef90fbdc0e82cf88b47 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-87 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K2-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H21-02 |
filingDate |
2009-09-18^^<http://www.w3.org/2001/XMLSchema#date> |
grantDate |
2012-06-19^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30d87840e4720953cca1ae3715253467 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eff1ba82704cae91f61589f6a1268404 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e13896e060bda8939bef25bd2394b596 |
publicationDate |
2012-06-19^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
US-8202544-B2 |
titleOfInvention |
High capacity non-viral vectors |
abstract |
Non-viral vectors for delivering agents to a site within the body of an animal comprise a biocompatible nanoparticle conjugated to an avidin/biotin complex and a water soluble linear polymer comprising multiple binding sites. The agents to be delivered are conjugated to each of the multiple binding sites, thereby increasing the loading capacity of the system. Where the agents comprise siRNA, each biotin/avidin complex may carry greater than four siRNA. The biocompatible nanoparticle may also comprise a fluorescent dye for in vivo imaging. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-2009220433-A1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-8669236-B2 |
priorityDate |
2008-09-18^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |