About: Emapalumab

An Entity of Type: monoclonal antibody, from Named Graph: http://dbpedia.org, within Data Space: dbpedia.org

Emapalumab, sold under the brand name Gamifant, is an anti-interferon-gamma (IFNγ) antibody medication used for the treatment of hemophagocytic lymphohistiocytosis (HLH), which has no cure. The most common side effects include infections, hypertension, infusion-related reactions, and pyrexia. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication.

Property Value
dbo:abstract
  • Emapalumab, sold under the brand name Gamifant, is an anti-interferon-gamma (IFNγ) antibody medication used for the treatment of hemophagocytic lymphohistiocytosis (HLH), which has no cure. The most common side effects include infections, hypertension, infusion-related reactions, and pyrexia. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication. (en)
  • La molecola Emapalumab, commercializzato a nome Gamifant, è un anti-interferone gamma (IFNγ) anticorpo usato per il trattamento Sindrome emofagocitica (HLH). (it)
dbo:alternativeName
  • Gamifant (en)
dbo:casNumber
  • 1709815-23-5
dbo:drugbank
  • DB14724
dbo:fdaUniiCode
  • 3S252O2Z4X
dbo:kegg
  • D11120
dbo:medlinePlus
  • a619024
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  • L04 (en)
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  • AA39 (en)
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  • 6430 (xsd:integer)
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  • 1709815 (xsd:integer)
dbp:chemspiderid
  • none (en)
dbp:dailymedid
  • Emapalumab (en)
dbp:drugbank
  • DB14724 (en)
dbp:h
  • 9898 (xsd:integer)
dbp:kegg
  • D11120 (en)
dbp:legalUs
  • Rx-only (en)
dbp:mabType
  • mab (en)
dbp:medlineplus
  • a619024 (en)
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  • 1718 (xsd:integer)
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  • 2038 (xsd:integer)
dbp:routesOfAdministration
  • Intravenous, parenteral (en)
dbp:s
  • 46 (xsd:integer)
dbp:source
  • u (en)
dbp:synonyms
  • NI-0501, emapalumab-lzsg (en)
dbp:target
dbp:tradename
  • Gamifant (en)
dbp:type
  • mab (en)
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  • 3 (xsd:integer)
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  • Emapalumab, sold under the brand name Gamifant, is an anti-interferon-gamma (IFNγ) antibody medication used for the treatment of hemophagocytic lymphohistiocytosis (HLH), which has no cure. The most common side effects include infections, hypertension, infusion-related reactions, and pyrexia. The U.S. Food and Drug Administration (FDA) considers it to be a first-in-class medication. (en)
  • La molecola Emapalumab, commercializzato a nome Gamifant, è un anti-interferone gamma (IFNγ) anticorpo usato per il trattamento Sindrome emofagocitica (HLH). (it)
rdfs:label
  • Emapalumab (en)
  • Emapalumab (it)
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